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ONTOLOGY REPORT - ANNOTATIONS


Term:fat-soluble vitamin biosynthetic process
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Accession:GO:0042362 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms:exact_synonym: fat-soluble vitamin anabolism;   fat-soluble vitamin biosynthesis;   fat-soluble vitamin formation;   fat-soluble vitamin synthesis


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:120,809,886...120,852,196
Ensembl chr15:120,809,959...120,852,193
JBrowse link
G CYP27B1 25-hydroxyvitamin D3 1alpha-hydroxylase IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,050,114...23,058,470
JBrowse link
G CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:44,375,432...44,394,122
Ensembl chr 2:44,375,520...44,396,367
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 25-hydroxyvitamin D3 1alpha-hydroxylase IEA Ensembl GO_REF:0000107 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,050,114...23,058,470
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor IEA Ensembl GO_REF:0000107 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,258...124,629,639
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,637...118,506,691
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,393...51,552,504
JBrowse link
G SNAI2 snail family transcriptional repressor 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,878...79,268,475
JBrowse link
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma IEA Ensembl GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G LOC110258578 interleukin-1 beta-like ISO (PMID:16720713), (PMID:17023519) BHF-UCL PMID:16720713, PMID:17023519
G TNF tumor necrosis factor IEA Ensembl GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma ISO (PMID:9282826) BHF-UCL PMID:9282826 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,848...32,482,752
JBrowse link
G TNF tumor necrosis factor ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VDR vitamin D receptor IEA Ensembl GO_REF:0000107 NCBI chr 5:78,205,807...78,266,505
Ensembl chr 5:78,205,810...78,267,321
JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLTP phospholipid transfer protein IEA Ensembl GO_REF:0000107 NCBI chr17:48,089,789...48,101,604
Ensembl chr17:48,089,785...48,101,515
JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBIAD1 UbiA prenyltransferase domain containing 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:71,419,559...71,431,275
Ensembl chr 6:71,419,602...71,433,210
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    metabolic process 10565
      small molecule metabolic process 1659
        vitamin metabolic process 70
          fat-soluble vitamin metabolic process 33
            fat-soluble vitamin biosynthetic process 13
              vitamin A biosynthetic process 0
              vitamin D biosynthetic process + 11
              vitamin E biosynthetic process + 1
              vitamin K biosynthetic process 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.