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ONTOLOGY REPORT - ANNOTATIONS


Term:fat-soluble vitamin biosynthetic process
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Accession:GO:0042362 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms:exact_synonym: fat-soluble vitamin anabolism;   fat-soluble vitamin biosynthesis;   fat-soluble vitamin formation;   fat-soluble vitamin synthesis


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:15465040)
Ensembl
RGD
PMID:15465040, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 ISO
IBA
(PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
PMID:21873635
(MGI:MGI:3590419|PMID:15972816)
RGD PMID:9415400, PMID:15795327, PMID:15972816, PMID:16549446, PMID:17023519, PMID:22862690, PMID:21873635 MGI:MGI:3590419, RGD:13792537 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 ISO (PMID:15465040), (PMID:18511070) RGD PMID:15465040, PMID:18511070 NCBI chr 1:184,060,521...184,106,604
Ensembl chr 1:184,093,920...184,106,200
JBrowse link
G LOC100909462 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 ISO (PMID:16549446) RGD PMID:16549446 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO
IEA
(PMID:15243130)
GO_REF:0000107
RGD
Ensembl
PMID:15243130 GO_REF:0000107 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 ISO (PMID:19502595) RGD PMID:19502595 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278, PMID:19502595 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO (PMID:9282826) RGD PMID:9282826 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta IEA
ISO
GO_REF:0000107
(PMID:16720713), (PMID:17023519)
Ensembl
RGD
PMID:16720713, PMID:17023519 GO_REF:0000107 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:1690216) RGD PMID:1690216 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO (PMID:9282826) RGD PMID:9282826 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:1690216) RGD PMID:1690216 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdr vitamin D receptor ISO
IEA
(MGI:MGI:1097206|PMID:9295274)
GO_REF:0000107
RGD
Ensembl
PMID:9295274 GO_REF:0000107, MGI:MGI:1097206 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pltp phospholipid transfer protein ISO MGI:MGI:2176342 (MGI:MGI:3622506|PMID:16467369) RGD PMID:16467369 MGI:MGI:3622506 NCBI chr 3:161,304,469...161,322,289
Ensembl chr 3:161,304,469...161,322,289
JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:20953171), (PMID:23169578)
UniProt
RGD
PMID:20953171, PMID:23169578, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:165,247,630...165,259,228
Ensembl chr 5:165,247,133...165,259,224
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      small molecule metabolic process 1869
        vitamin metabolic process 81
          fat-soluble vitamin metabolic process 39
            fat-soluble vitamin biosynthetic process 14
              vitamin A biosynthetic process 0
              vitamin D biosynthetic process + 12
              vitamin E biosynthetic process + 1
              vitamin K biosynthetic process 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.