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ONTOLOGY REPORT - ANNOTATIONS


Term:fat-soluble vitamin biosynthetic process
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Accession:GO:0042362 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
Synonyms:exact_synonym: fat-soluble vitamin anabolism;   fat-soluble vitamin biosynthesis;   fat-soluble vitamin formation;   fat-soluble vitamin synthesis


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC101963150 sterol 26-hydroxylase, mitochondrial ISO (PMID:15465040) UniProt PMID:15465040 NCBI chrNW_004936569:1,213,700...1,250,181 JBrowse link
G LOC101972957 vitamin D 25-hydroxylase ISO (PMID:15465040), (PMID:18511070) UniProt PMID:15465040, PMID:18511070 NCBI chrNW_004936528:3,881,630...3,897,613 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO (MGI:MGI:3590419|PMID:15972816)
(PMID:15795327), (PMID:16549446), (PMID:17023519), (PMID:22862690), (PMID:9415400)
UniProt PMID:9415400, PMID:15795327, PMID:15972816, PMID:16549446, PMID:17023519, PMID:22862690 MGI:MGI:3590419 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chrNW_004936537:6,610,565...6,618,509 JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chrNW_004936646:1,899,686...1,904,104 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chrNW_004936520:733,760...850,563 JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 ISO (PMID:19502595) BHF-UCL PMID:19502595 NCBI chrNW_004936514:4,456,498...4,462,436 JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278, PMID:19502595 NCBI chrNW_004936590:3,813,916...3,817,642 JBrowse link
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO (PMID:9282826) BHF-UCL PMID:9282826 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Il1b interleukin 1 beta ISO (PMID:16720713), (PMID:17023519) BHF-UCL PMID:16720713, PMID:17023519 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G Tnf tumor necrosis factor ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma ISO (PMID:9282826) BHF-UCL PMID:9282826 NCBI chrNW_004936545:6,139,130...6,144,543 JBrowse link
G Tnf tumor necrosis factor ISO (PMID:1690216) BHF-UCL PMID:1690216 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vdr vitamin D receptor ISO (MGI:MGI:1097206|PMID:9295274) BHF-UCL PMID:9295274 MGI:MGI:1097206 NCBI chrNW_004936512:5,741,836...5,800,999 JBrowse link
vitamin E biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pltp phospholipid transfer protein ISO (MGI:MGI:3622506|PMID:16467369) MGI PMID:16467369 MGI:MGI:3622506 NCBI chrNW_004936514:7,121,023...7,131,475 JBrowse link
vitamin K biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO (PMID:23169578)
(PMID:20953171)
UniProtKB PMID:20953171, PMID:23169578 NCBI chrNW_004936474:284,630...293,090 JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 11962
    metabolic process 7653
      small molecule metabolic process 1240
        vitamin metabolic process 61
          fat-soluble vitamin metabolic process 30
            fat-soluble vitamin biosynthetic process 13
              vitamin A biosynthetic process 0
              vitamin D biosynthetic process + 11
              vitamin E biosynthetic process + 1
              vitamin K biosynthetic process 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.