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ONTOLOGY REPORT - ANNOTATIONS


Term:vitamin D biosynthetic process
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Accession:GO:0042368 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
Synonyms:exact_synonym: vitamin D anabolism;   vitamin D biosynthesis;   vitamin D formation;   vitamin D synthesis
 narrow_synonym: calciferol biosynthesis;   calciferol biosynthetic process;   cholecalciferol biosynthesis;   cholecalciferol biosynthetic process;   ergocalciferol biosynthesis;   ergocalciferol biosynthetic process


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calcitriol biosynthetic process from calciol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:1600115
RGD:1624291
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 JBrowse link 1 184,060,521 184,106,604 RGD:1624291
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:1624291
RGD:1600115
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Snai1 snail family transcriptional repressor 1 JBrowse link 3 164,274,710 164,279,199 RGD:1624291
G Snai2 snail family transcriptional repressor 2 JBrowse link 11 90,404,421 90,406,730 RGD:1624291
positive regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
positive regulation of vitamin D biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      organic substance metabolic process 11027
        organic substance biosynthetic process 5871
          organic hydroxy compound biosynthetic process 238
            vitamin D biosynthetic process 11
              calcitriol biosynthetic process from calciol 3
              negative regulation of vitamin D biosynthetic process + 5
              positive regulation of vitamin D biosynthetic process + 3
              regulation of vitamin D biosynthetic process + 9
              vitamin D3 biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      primary metabolic process 10478
        lipid metabolic process 1315
          steroid metabolic process 306
            steroid biosynthetic process 159
              vitamin D biosynthetic process 11
                calcitriol biosynthetic process from calciol 3
                negative regulation of vitamin D biosynthetic process + 5
                positive regulation of vitamin D biosynthetic process + 3
                regulation of vitamin D biosynthetic process + 9
                vitamin D3 biosynthetic process 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.