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ONTOLOGY REPORT - ANNOTATIONS


Term:serotonin biosynthetic process
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Accession:GO:0042427 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
Synonyms:exact_synonym: serotonin anabolism;   serotonin biosynthesis;   serotonin formation;   serotonin synthesis
 xref: Wikipedia:Serotonin


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serotonin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:5129182
G Tph2 tryptophan hydroxylase 2 JBrowse link 7 58,042,279 58,149,220 RGD:1600115
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:11353778
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:625621

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    metabolic process 10866
      cellular metabolic process 9928
        neurotransmitter metabolic process 156
          neurotransmitter biosynthetic process 110
            serotonin biosynthetic process 4
              negative regulation of serotonin biosynthetic process 0
              positive regulation of serotonin biosynthetic process 0
              regulation of serotonin biosynthetic process + 0
              serotonin biosynthetic process from tryptophan + 2
Path 2
Term Annotations click to browse term
  biological_process 18179
    biological regulation 12814
      regulation of biological quality 4178
        regulation of neurotransmitter levels 405
          neurotransmitter metabolic process 156
            neurotransmitter biosynthetic process 110
              serotonin biosynthetic process 4
                negative regulation of serotonin biosynthetic process 0
                positive regulation of serotonin biosynthetic process 0
                regulation of serotonin biosynthetic process + 0
                serotonin biosynthetic process from tryptophan + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.