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ONTOLOGY REPORT - ANNOTATIONS


Term:indole-containing compound metabolic process
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Accession:GO:0042430 term browser browse the term
Definition:The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.
Synonyms:exact_synonym: indole and derivative metabolic process;   indole and derivative metabolism;   indole-containing compound metabolism;   ketole metabolic process;   ketole metabolism
 narrow_synonym: indole derivative metabolic process;   indole derivative metabolism
 alt_id: GO:0042434


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'de novo' NAD biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1600115
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:13792537
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:13792537
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1600115
indole metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc34a1 solute carrier family 34 member 1 JBrowse link 17 9,747,766 9,762,739 RGD:7243183
melatonin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aanat aralkylamine N-acetyltransferase JBrowse link 10 105,568,091 105,572,407 RGD:67926
RGD:13792537
RGD:1600115
RGD:1624291
G Asmt acetylserotonin O-methyltransferase JBrowse link 12 18,521,383 18,527,036 RGD:1299464
RGD:13792537
RGD:1624291
RGD:1600115
RGD:1359073
melatonin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:4890365
serotonin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:5129182
G Tph2 tryptophan hydroxylase 2 JBrowse link 7 58,042,279 58,149,220 RGD:1600115
serotonin biosynthetic process from tryptophan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:11353778
G Tph1 tryptophan hydroxylase 1 JBrowse link 1 102,669,868 102,699,442 RGD:625621
serotonin metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 JBrowse link 4 145,704,779 145,948,997 RGD:1624291
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Btbd9 BTB domain containing 9 JBrowse link 20 8,899,286 9,253,936 RGD:1624291
RGD:1600115
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:1624291
RGD:1600115
G Htr1a 5-hydroxytryptamine receptor 1A JBrowse link 2 36,246,628 36,247,896 RGD:1624291
RGD:1600115
G Maoa monoamine oxidase A JBrowse link X 6,554,698 6,620,722 RGD:1600709
RGD:1600713
G Pde1b phosphodiesterase 1B JBrowse link 7 145,117,951 145,147,711 RGD:1624291
RGD:1600115
G Rnf180 ring finger protein 180 JBrowse link 2 35,718,100 35,892,578 RGD:1624291
RGD:1600115
G Spr sepiapterin reductase JBrowse link 4 116,912,343 116,916,073 RGD:1624291
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:4891926
tryptophan catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acmsd aminocarboxymuconate semialdehyde decarboxylase JBrowse link 13 44,424,689 44,468,734 RGD:70243
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:1600115
G Kmo kynurenine 3-monooxygenase JBrowse link 13 93,684,324 93,715,378 RGD:1600115
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:1624291
tryptophan catabolic process to acetyl-CoA term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:2303721
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2303721
RGD:13792537
tryptophan catabolic process to kynurenine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Afmid arylformamidase JBrowse link 10 106,828,963 106,844,314 RGD:1624291
RGD:13792537
RGD:1600115
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:2290190
RGD:13792537
RGD:1624291
RGD:1600115
RGD:2290543
G Ido2 indoleamine 2,3-dioxygenase 2 JBrowse link 16 72,232,852 72,291,227 RGD:1600115
RGD:13792537
RGD:1624291
G Kynu kynureninase JBrowse link 3 28,416,926 28,566,939 RGD:13792537
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:1600115
RGD:1624291
tryptophan metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:2290190
RGD:2291804
RGD:2290313

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18157
    metabolic process 10837
      cellular metabolic process 9903
        cellular aromatic compound metabolic process 5168
          indole-containing compound metabolic process 26
            brevianamide F metabolic process + 0
            fumiquinazoline F metabolic process + 0
            indolalkylamine metabolic process + 11
            indole glucosinolate metabolic process + 0
            indole metabolic process + 1
            indole phytoalexin metabolic process + 0
            indole-containing compound biosynthetic process + 6
            indole-containing compound catabolic process + 8
            indoleacetic acid metabolic process + 0
            indolebutyric acid metabolic process 0
            melatonin metabolic process + 3
            serotonin metabolic process + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.