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ONTOLOGY REPORT - ANNOTATIONS


Term:melanin biosynthetic process
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Accession:GO:0042438 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
Synonyms:exact_synonym: melanin anabolism;   melanin biosynthesis;   melanin formation;   melanin synthesis


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melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:1624291
RGD:1600115
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
G Ddt D-dopachrome tautomerase JBrowse link 20 13,827,153 13,829,624 RGD:1600115
G Mc1r melanocortin 1 receptor JBrowse link 19 56,215,420 56,219,987 RGD:1624291
G Myo5a myosin VA JBrowse link 8 82,038,966 82,156,507 RGD:1624291
RGD:1600115
G Oca2 OCA2 melanosomal transmembrane protein JBrowse link 1 114,661,970 114,987,433 RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 JBrowse link 8 103,503,982 103,554,905 RGD:1624291
RGD:1600115
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:1624291
RGD:13792537
melanin biosynthetic process from tyrosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dct dopachrome tautomerase JBrowse link 15 103,208,174 103,245,033 RGD:1624291
negative regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mfsd12 major facilitator superfamily domain containing 12 JBrowse link 7 11,214,832 11,223,713 RGD:1600115
RGD:1624291
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1624291
RGD:1600115
G Slc24a5 solute carrier family 24 member 5 JBrowse link 3 117,335,212 117,354,480 RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
positive regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 JBrowse link 16 2,560,103 2,602,035 RGD:1624291
G Asip agouti signaling protein JBrowse link 3 150,492,010 150,579,870 RGD:1624291
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:1624291
G Gipc1 GIPC PDZ domain containing family, member 1 JBrowse link 19 24,786,604 24,798,231 RGD:1600115
RGD:1624291
G Pmel premelanosome protein JBrowse link 7 3,133,347 3,143,827 RGD:1624291
G Tyrp1 tyrosinase-related protein 1 JBrowse link 5 98,387,291 98,406,083 RGD:1624291
regulation of melanin biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      secondary metabolic process 76
        secondary metabolite biosynthetic process 25
          melanin biosynthetic process 19
            melanin biosynthetic process from tyrosine 1
            negative regulation of melanin biosynthetic process 4
            positive regulation of melanin biosynthetic process 6
            regulation of melanin biosynthetic process + 11
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11638
      cellular metabolic process 10639
        cellular aromatic compound metabolic process 5503
          phenol-containing compound metabolic process 122
            melanin metabolic process 21
              melanin biosynthetic process 19
                melanin biosynthetic process from tyrosine 1
                negative regulation of melanin biosynthetic process 4
                positive regulation of melanin biosynthetic process 6
                regulation of melanin biosynthetic process + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.