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ONTOLOGY REPORT - ANNOTATIONS


Term:inner ear auditory receptor cell differentiation
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Accession:GO:0042491 term browser browse the term
Definition:The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell.
Comment:Note that this term refers to the mechanosensory hair cells of the inner ear.
Synonyms:exact_synonym: auditory hair cell differentiation
 related_synonym: auditory receptor cell differentiation


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inner ear auditory receptor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atoh1 atonal bHLH transcription factor 1 JBrowse link 4 95,498,003 95,500,098 RGD:1624291
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:1624291
G Cux1 cut-like homeobox 1 JBrowse link 12 23,150,886 23,470,095 RGD:1624291
G Gfi1 growth factor independent 1 transcriptional repressor JBrowse link 14 3,058,035 3,073,332 RGD:1624291
G Grxcr1 glutaredoxin and cysteine rich domain containing 1 JBrowse link 14 41,663,688 41,787,331 RGD:1624291
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:1582345
RGD:1600115
RGD:1624291
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 JBrowse link 15 344,204 1,048,849 RGD:1624291
G Mcoln3 mucolipin 3 JBrowse link 2 251,930,532 252,007,722 RGD:1624291
G Myo6 myosin VI JBrowse link 8 87,583,649 87,731,271 RGD:1624291
RGD:13792537
G Myo7a myosin VIIA JBrowse link 1 163,001,313 163,071,545 RGD:1624291
G Pcdh15 protocadherin related 15 JBrowse link 20 14,952,213 15,334,745 RGD:1624291
G Pls3 plastin 3 JBrowse link X 119,030,311 119,124,268 RGD:731234
G Pou4f3 POU class 4 homeobox 3 JBrowse link 18 36,713,869 36,716,461 RGD:1624291
G Ush1c USH1 protein network component harmonin JBrowse link 1 102,207,096 102,256,779 RGD:1624291
RGD:13792537
auditory receptor cell development term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alg10 ALG10, alpha-1,2-glucosyltransferase JBrowse link 7 131,330,913 131,336,183 RGD:1624291
G Clrn1 clarin 1 JBrowse link 2 149,049,925 149,088,787 RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:1624291
RGD:1600115
G Lrtomt leucine rich transmembrane and O-methyltransferase domain containing JBrowse link 1 166,985,468 166,989,681 RGD:1624291
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 JBrowse link 10 61,456,144 61,577,412 RGD:1624291
G Pdzd7 PDZ domain containing 7 JBrowse link 1 264,776,393 264,796,206 RGD:1624291
G Slc4a7 solute carrier family 4 member 7 JBrowse link 15 11,832,611 11,912,923 RGD:1624291
RGD:13792537
G Tmc1 transmembrane channel-like 1 JBrowse link 1 238,336,919 238,525,792 RGD:1624291
auditory receptor cell fate commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:8553270
G Jag2 jagged canonical Notch ligand 2 JBrowse link 6 137,711,144 137,733,331 RGD:1600115
RGD:8553713
RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
G Rbpj recombination signal binding protein for immunoglobulin kappa J region JBrowse link 14 59,657,738 59,865,427 RGD:1624291
auditory receptor cell fate determination term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atoh1 atonal bHLH transcription factor 1 JBrowse link 4 95,498,003 95,500,098 RGD:1624291
auditory receptor cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atoh1 atonal bHLH transcription factor 1 JBrowse link 4 95,498,003 95,500,098 RGD:1624291
auditory receptor cell morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mir96 microRNA 96 JBrowse link 4 57,463,366 57,463,471 RGD:1624291
G Rac1 Rac family small GTPase 1 JBrowse link 12 13,090,316 13,111,841 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:1624291
G Sec24b SEC24 homolog B, COPII coat complex component JBrowse link 2 230,286,886 230,356,887 RGD:1624291
G Slitrk6 SLIT and NTRK-like family, member 6 JBrowse link 15 95,507,632 95,514,259 RGD:1624291
G Wdpcp WD repeat containing planar cell polarity effector JBrowse link 14 106,393,959 106,759,511 RGD:1624291
RGD:1600115
auditory receptor cell stereocilium organization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 JBrowse link 4 145,704,779 145,948,997 RGD:1624291
G Cdh23 cadherin-related 23 JBrowse link 20 29,857,018 30,263,758 RGD:1624291
G Clic5 chloride intracellular channel 5 JBrowse link 9 19,121,676 19,372,673 RGD:1624291
RGD:13792537
G Clrn1 clarin 1 JBrowse link 2 149,049,925 149,088,787 RGD:1600115
RGD:1624291
G Grxcr2 glutaredoxin and cysteine rich domain containing 2 JBrowse link 18 36,308,925 36,334,643 RGD:1624291
G Lhfpl5 LHFPL tetraspan subfamily member 5 JBrowse link 20 5,815,837 5,826,137 RGD:1624291
G Myo3a myosin IIIA JBrowse link 17 88,952,635 89,167,538 RGD:1624291
G Myo3b myosin IIIB JBrowse link 3 56,355,433 56,717,740 RGD:1624291
G Myo7a myosin VIIA JBrowse link 1 163,001,313 163,071,545 RGD:1624291
G Pcdh15 protocadherin related 15 JBrowse link 20 14,952,213 15,334,745 RGD:1624291
G Pdzd7 PDZ domain containing 7 JBrowse link 1 264,776,393 264,796,206 RGD:1624291
RGD:13792537
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1600115
RGD:1624291
G Ripor2 RHO family interacting cell polarization regulator 2 JBrowse link 17 42,324,594 42,549,907 RGD:1624291
G Scrib scribble planar cell polarity protein JBrowse link 7 117,105,810 117,128,802 RGD:1624291
G Sec24b SEC24 homolog B, COPII coat complex component JBrowse link 2 230,286,886 230,356,887 RGD:1624291
G Slc9a3r1 SLC9A3 regulator 1 JBrowse link 10 103,713,045 103,730,145 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1600115
RGD:1624291
G Strc stereocilin JBrowse link 3 113,324,403 113,343,513 RGD:1624291
G Tprn taperin JBrowse link 3 2,480,232 2,487,710 RGD:1624291
G Triobp TRIO and F-actin binding protein JBrowse link 7 120,173,892 120,237,145 RGD:1624291
G Whrn whirlin JBrowse link 5 79,235,541 79,317,206 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dll1 delta like canonical Notch ligand 1 JBrowse link 1 57,318,621 57,326,732 RGD:1624291
RGD:1600115
G Hes1 hes family bHLH transcription factor 1 JBrowse link 11 74,312,837 74,315,249 RGD:1600115
RGD:1624291
G Hes5 hes family bHLH transcription factor 5 JBrowse link 5 172,364,421 172,365,188 RGD:1624291
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
positive regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atoh1 atonal bHLH transcription factor 1 JBrowse link 4 95,498,003 95,500,098 RGD:1624291
regulation of inner ear auditory receptor cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 JBrowse link 2 95,320,147 95,322,701 RGD:1624291
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 JBrowse link 1 29,191,170 29,201,257 RGD:1624291
G Mycl MYCL proto-oncogene, bHLH transcription factor JBrowse link 5 140,691,947 140,698,837 RGD:1624291
G Mycn MYCN proto-oncogene, bHLH transcription factor JBrowse link 6 38,222,554 38,228,419 RGD:1624291
RGD:1600115
G Notch1 notch receptor 1 JBrowse link 3 3,905,562 3,951,015 RGD:1624291
regulation of inner ear auditory receptor cell fate specification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Esrp1 epithelial splicing regulatory protein 1 JBrowse link 5 24,576,988 24,631,758 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        inner ear development 240
          inner ear receptor cell differentiation 83
            inner ear auditory receptor cell differentiation 53
              auditory receptor cell development + 31
              auditory receptor cell fate commitment + 6
              negative regulation of inner ear auditory receptor cell differentiation + 4
              positive regulation of inner ear auditory receptor cell differentiation 1
              regulation of inner ear auditory receptor cell differentiation + 10
Path 2
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        multicellular organism development 5623
          system development 5157
            nervous system development 2641
              neurogenesis 1909
                generation of neurons 1770
                  neuron differentiation 1595
                    mechanoreceptor differentiation 91
                      inner ear receptor cell differentiation 83
                        inner ear auditory receptor cell differentiation 53
                          auditory receptor cell development + 31
                          auditory receptor cell fate commitment + 6
                          negative regulation of inner ear auditory receptor cell differentiation + 4
                          positive regulation of inner ear auditory receptor cell differentiation 1
                          regulation of inner ear auditory receptor cell differentiation + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.