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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of mesodermal cell fate specification
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Accession:GO:0042662 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.
Synonyms:exact_synonym: down regulation of mesodermal cell fate specification;   downregulation of mesodermal cell fate specification;   suppression of mesodermal cell fate
 narrow_synonym: inhibition of mesodermal cell fate specification


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negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) BHF-UCL PMID:20559569 NCBI chrNW_004955425:7,353,964...7,357,599 JBrowse link
G Sfrp2 secreted frizzled related protein 2 ISO (MGI:MGI:3711603|PMID:17462603) MGI PMID:17462603 MGI:MGI:3711603 NCBI chrNW_004955471:8,103,937...8,112,596
Ensembl chrNW_004955471:8,103,783...8,112,321
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11889
    negative regulation of biological process 4604
      negative regulation of developmental process 891
        negative regulation of cell differentiation 636
          negative regulation of mesodermal cell differentiation 2
            negative regulation of mesodermal cell fate specification 2
              negative regulation of axial mesodermal cell fate specification 0
              negative regulation of intermediate mesodermal cell fate specification 0
              negative regulation of lateral mesodermal cell fate specification 0
              negative regulation of paraxial mesodermal cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 11889
    developmental process 5616
      anatomical structure development 5254
        multicellular organism development 4812
          embryo development 1169
            embryonic morphogenesis 626
              gastrulation 176
                formation of primary germ layer 115
                  mesoderm formation 67
                    mesodermal cell differentiation 29
                      mesodermal cell fate commitment 15
                        mesodermal cell fate specification 11
                          regulation of mesodermal cell fate specification 5
                            negative regulation of mesodermal cell fate specification 2
                              negative regulation of axial mesodermal cell fate specification 0
                              negative regulation of intermediate mesodermal cell fate specification 0
                              negative regulation of lateral mesodermal cell fate specification 0
                              negative regulation of paraxial mesodermal cell fate specification 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.