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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of mesodermal cell fate specification
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Accession:GO:0042662 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.
Synonyms:exact_synonym: down regulation of mesodermal cell fate specification;   downregulation of mesodermal cell fate specification;   suppression of mesodermal cell fate
 narrow_synonym: inhibition of mesodermal cell fate specification


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negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 IDA (PMID:20559569) BHF-UCL PMID:20559569 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
JBrowse link
G MESP1 mesoderm posterior bHLH transcription factor 1 ISS BHF-UCL GO_REF:0000024 NCBI chr15:89,734,772...89,751,309
Ensembl chr15:89,748,661...89,751,310
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    negative regulation of biological process 6172
      negative regulation of developmental process 1060
        negative regulation of cell differentiation 779
          negative regulation of mesodermal cell differentiation 3
            negative regulation of mesodermal cell fate specification 3
              negative regulation of axial mesodermal cell fate specification 0
              negative regulation of intermediate mesodermal cell fate specification 0
              negative regulation of lateral mesodermal cell fate specification 0
              negative regulation of paraxial mesodermal cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 18670
    developmental process 7464
      anatomical structure development 6871
        multicellular organism development 6344
          embryo development 1324
            embryonic morphogenesis 700
              gastrulation 208
                formation of primary germ layer 132
                  mesoderm formation 79
                    mesodermal cell differentiation 34
                      mesodermal cell fate commitment 20
                        mesodermal cell fate specification 13
                          regulation of mesodermal cell fate specification 6
                            negative regulation of mesodermal cell fate specification 3
                              negative regulation of axial mesodermal cell fate specification 0
                              negative regulation of intermediate mesodermal cell fate specification 0
                              negative regulation of lateral mesodermal cell fate specification 0
                              negative regulation of paraxial mesodermal cell fate specification 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.