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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of mesodermal cell fate specification
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Accession:GO:0042662 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.
Synonyms:exact_synonym: down regulation of mesodermal cell fate specification;   downregulation of mesodermal cell fate specification;   suppression of mesodermal cell fate
 narrow_synonym: inhibition of mesodermal cell fate specification


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negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr19:30,545,876...30,549,496
Ensembl chr19:30,545,863...30,549,665
JBrowse link
G Mesp1 mesoderm posterior 1 IDA (MGI:MGI:4441249|PMID:18593560) BHF-UCL PMID:18593560 MGI:MGI:4441249 NCBI chr 7:79,792,241...79,793,590
Ensembl chr 7:79,792,241...79,793,788
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 IGI (MGI:MGI:3711603|PMID:17462603) MGI PMID:17462603 MGI:MGI:3711603 NCBI chr 3:83,765,750...83,774,314
Ensembl chr 3:83,766,321...83,774,316
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23392
    negative regulation of biological process 5653
      negative regulation of developmental process 1030
        negative regulation of cell differentiation 750
          negative regulation of mesodermal cell differentiation 3
            negative regulation of mesodermal cell fate specification 3
              negative regulation of axial mesodermal cell fate specification 0
              negative regulation of intermediate mesodermal cell fate specification 0
              negative regulation of lateral mesodermal cell fate specification 0
              negative regulation of paraxial mesodermal cell fate specification 0
Path 2
Term Annotations click to browse term
  biological_process 23392
    developmental process 7030
      anatomical structure development 6504
        multicellular organism development 5967
          embryo development 1302
            embryonic morphogenesis 679
              gastrulation 202
                formation of primary germ layer 127
                  mesoderm formation 74
                    mesodermal cell differentiation 31
                      mesodermal cell fate commitment 17
                        mesodermal cell fate specification 12
                          regulation of mesodermal cell fate specification 6
                            negative regulation of mesodermal cell fate specification 3
                              negative regulation of axial mesodermal cell fate specification 0
                              negative regulation of intermediate mesodermal cell fate specification 0
                              negative regulation of lateral mesodermal cell fate specification 0
                              negative regulation of paraxial mesodermal cell fate specification 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.