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ONTOLOGY REPORT - ANNOTATIONS


Term:drug catabolic process
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Accession:GO:0042737 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
Synonyms:exact_synonym: drug breakdown;   drug catabolism;   drug degradation


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drug catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO (PMID:18356043) RGD PMID:18356043 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO (PMID:15039299) RGD PMID:15039299 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 ISO (PMID:15039299) RGD PMID:15039299 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 ISO MGI:MGI:5487815 (MGI:MGI:5487534|PMID:19262426) RGD PMID:19262426 MGI:MGI:5487534 NCBI chr13:80,685,385...80,703,575
Ensembl chr13:80,685,325...80,703,615
JBrowse link
exogenous drug catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07066946.2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 9:23,431,573...23,454,316 JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 ISO (PMID:18619574) RGD PMID:18619574 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,744,229...83,766,490
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2ab1 cytochrome P450, family 2, subfamily ab, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:84,506,074...84,514,164
Ensembl chr11:84,506,703...84,514,328
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,511,167...83,522,965
Ensembl chr 1:83,511,167...83,584,589
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:251,325,923...251,338,404
Ensembl chr 1:251,325,923...251,338,358
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,389,783...83,418,613
Ensembl chr 1:83,389,788...83,418,777
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 ISO
IBA
(PMID:19029318)
PMID:21873635
RGD PMID:19029318, PMID:21873635 RGD:13792537 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:258,709,726...258,766,873
Ensembl chr 1:258,709,721...258,766,881
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:258,796,624...258,877,023
Ensembl chr 1:258,796,622...258,877,045
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:259,257,658...259,297,270
Ensembl chr 1:259,257,657...259,287,684
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:263,778,510...263,803,166
Ensembl chr 1:263,778,516...263,803,150
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:258,074,797...258,139,176
Ensembl chr 1:258,074,860...258,139,176
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 ISO
IBA
(PMID:19029318)
PMID:21873635
RGD PMID:19029318, PMID:21873635 RGD:13792537 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:147,422,999...148,119,979
Ensembl chr 1:148,053,687...148,119,857
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 ISO (PMID:18619574) RGD PMID:18619574 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2c80 cytochrome P450, family 2, subfamily c, polypeptide 80 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 NOT ISO
IBA
(PMID:15051713)
PMID:21873635
(PMID:18838503)
RGD PMID:15051713, PMID:18838503, PMID:21873635 RGD:13792537 NCBI chr 7:123,625,641...123,630,045
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2d5 cytochrome P450, family 2, subfamily d, polypeptide 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:123,616,596...123,621,102
Ensembl chr 7:123,616,596...123,621,102
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,626,639...83,638,154
Ensembl chr 1:83,626,639...83,637,780
JBrowse link
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:115,067,847...115,101,961
Ensembl chr 5:115,021,723...115,222,084
JBrowse link
G Cyp2j16 cytochrome P450, family 2, subfamily j, polypeptide 16 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:119,454,997...119,505,533
Ensembl chr 5:119,454,828...119,505,586
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:115,196,982...115,222,084 JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:184,060,521...184,106,604
Ensembl chr 1:184,093,920...184,106,200
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:236,414,131...236,431,650
Ensembl chr 2:236,414,135...236,431,683
JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:17,382,749...17,387,909
Ensembl chr12:17,383,159...17,387,879
JBrowse link
G LOC100361492 cytochrome P450, family 2, subfamily c, polypeptide 55-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:258,210,311...258,252,829
Ensembl chr 1:258,210,344...258,252,448
JBrowse link
G LOC100361547 Cytochrome P450, family 2, subfamily c, polypeptide 7-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:148,232,438...148,287,458
Ensembl chr 1:148,240,504...148,287,217
JBrowse link
G LOC100910127 cytochrome P450 2B15-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:251,351,807...251,365,431
Ensembl chr 1:251,352,961...251,365,385
JBrowse link
G LOC103691072 cytochrome P450 2B15-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,571,210...83,584,833
Ensembl chr 1:83,573,032...83,579,836
JBrowse link
G LOC103691092 cytochrome P450 2B9-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:83,296,869...83,315,317
Ensembl chr 1:83,289,743...83,315,317
JBrowse link
G Nos1 nitric oxide synthase 1 ISO
IEA
MGI:MGI:1857227 (MGI:MGI:1931387|PMID:11158245)
GO_REF:0000107
RGD
Ensembl
PMID:11158245 GO_REF:0000107, MGI:MGI:1931387 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 ISO
ISS
(PMID:12578355)
GO_REF:0000024
RGD
UniProt
PMID:12578355 GO_REF:0000024 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nudt15 nudix hydrolase 15 ISO (PMID:26878724) RGD PMID:26878724 NCBI chr15:55,417,774...55,456,698
Ensembl chr15:55,419,502...55,456,698
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      cellular metabolic process 11065
        drug metabolic process 72
          drug catabolic process 49
            cocaine catabolic process 0
            endogenous drug catabolic process + 0
            exogenous drug catabolic process + 47
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.