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ONTOLOGY REPORT - ANNOTATIONS


Term:hydrogen peroxide metabolic process
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Accession:GO:0042743 term browser browse the term
Definition:The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
Synonyms:exact_synonym: H2O2 metabolic process;   hydrogen peroxide metabolism


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hydrogen peroxide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:1624291
G Cyct cytochrome c, testis JBrowse link 3 63,204,779 63,211,847 RGD:1624291
G Duoxa1 dual oxidase maturation factor 1 JBrowse link 3 114,241,057 114,251,720 RGD:1624291
G Duoxa2 dual oxidase maturation factor 2 JBrowse link 3 114,236,718 114,240,086 RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:5131481
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:1580833
hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyba cytochrome b-245 alpha chain JBrowse link 19 55,249,634 55,257,824 RGD:2317869
G Cybb cytochrome b-245 beta chain JBrowse link X 14,578,330 14,610,049 RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:1624291
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:1624291
G Duox1 dual oxidase 1 JBrowse link 3 114,251,794 114,286,827 RGD:1600115
RGD:1624291
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1600115
RGD:1624291
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 12 25,497,104 25,506,300 RGD:1624291
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:1581090
RGD:1600115
RGD:1624291
RGD:1601266
RGD:634854
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:2291946
hydrogen peroxide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:1624291
RGD:1600115
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1358492
RGD:13792537
RGD:1624291
RGD:2292202
G Duox1 dual oxidase 1 JBrowse link 3 114,251,794 114,286,827 RGD:1600115
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1600115
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624364
RGD:1600115
RGD:13792537
RGD:1624291
G Gpx3 glutathione peroxidase 3 JBrowse link 10 40,247,436 40,255,423 RGD:1624364
RGD:13792537
RGD:1600115
RGD:1624291
G Hba-a1 hemoglobin alpha, adult chain 1 JBrowse link 10 15,602,794 15,603,649 RGD:13792537
G Hba-a2 hemoglobin alpha, adult chain 2 JBrowse link 10 15,589,364 15,590,207 RGD:1624291
RGD:13792537
G Hba-a3 hemoglobin alpha, adult chain 3 JBrowse link 10 15,577,249 15,577,977 RGD:13792537
RGD:1624291
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:1624291
RGD:13792537
G Hbb-bs hemoglobin, beta adult s chain JBrowse link 1 168,964,202 168,965,568 RGD:13792537
G Hbe1 hemoglobin subunit epsilon 1 JBrowse link 1 169,003,904 169,005,184 RGD:13792537
G Hbe2 hemoglobin, epsilon 2 JBrowse link 1 169,000,133 169,001,761 RGD:13792537
G Hbg1 hemoglobin subunit gamma 1 JBrowse link 1 168,992,841 168,994,219 RGD:13792537
G Hbq1b hemoglobin subunit theta 1B JBrowse link 10 15,599,821 15,602,680 RGD:13792537
G Hbz hemoglobin subunit zeta JBrowse link 10 15,609,348 15,610,826 RGD:13792537
G LOC100134871 beta globin minor gene JBrowse link 1 168,957,460 168,958,836 RGD:13792537
G LOC103694857 hemoglobin subunit beta-2 RGD:13792537
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:1624291
G Prdx1 peroxiredoxin 1 JBrowse link 5 135,536,413 135,551,986 RGD:1624291
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
RGD:1600115
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:1600115
RGD:1624291
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1624291
RGD:13792537
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:729495
G Pxdn peroxidasin JBrowse link 6 48,866,496 48,982,368 RGD:1624291
G Tpo thyroid peroxidase JBrowse link 6 49,020,918 49,089,855 RGD:1600115
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:634378
negative regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctns cystinosin, lysosomal cystine transporter JBrowse link 10 59,749,250 59,772,475 RGD:12910938
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:7349317
G Fyn FYN proto-oncogene, Src family tyrosine kinase JBrowse link 20 44,436,354 44,630,316 RGD:13601987
G Mpv17l MPV17 mitochondrial inner membrane protein like JBrowse link 10 3,321,488 3,359,219 RGD:1624291
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:8694322
negative regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1624291
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:625483
negative regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:1624291
RGD:1600115
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10003093
positive regulation of hydrogen peroxide biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Duoxa1 dual oxidase maturation factor 1 JBrowse link 3 114,241,057 114,251,720 RGD:1624291
G Duoxa2 dual oxidase maturation factor 2 JBrowse link 3 114,236,718 114,240,086 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:12910740
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:13506652
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:27095884
G Zfp13 zinc finger protein 13 JBrowse link 10 12,908,643 12,916,784 RGD:1624291
positive regulation of hydrogen peroxide catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nnt nicotinamide nucleotide transhydrogenase JBrowse link 2 52,189,523 52,283,095 RGD:13513981
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
regulation of hydrogen peroxide metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:2290474
G Noxa1 NADPH oxidase activator 1 JBrowse link 3 2,299,676 2,309,491 RGD:1624291
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:1624291
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
RGD:1600115

Term paths to the root
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  biological_process 19858
    cellular process 18618
      cellular metabolic process 10918
        reactive oxygen species metabolic process 305
          hydrogen peroxide metabolic process 57
            detoxification of hydrogen peroxide + 0
            hydrogen peroxide biosynthetic process + 19
            hydrogen peroxide catabolic process + 31
            negative regulation of hydrogen peroxide metabolic process + 9
            positive regulation of hydrogen peroxide metabolic process + 8
            regulation of hydrogen peroxide metabolic process + 21
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.