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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of circadian sleep/wake cycle
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Accession:GO:0042749 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.


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regulation of circadian sleep/wake cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1d1 nuclear receptor subfamily 1 group D member 1 ISO (MGI:6283959|PMID:30792350) UniProt PMID:30792350 MGI:6283959 NCBI chrNW_004936490:15,206,194...15,213,858 JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO RGD PMID:19491711 RGD:2317916 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO (PMID:18329818) BHF-UCL PMID:18329818 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO RGD PMID:18466985 RGD:6480669 NCBI chrNW_004936601:3,569,626...3,626,782 JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chrNW_004936567:1,430,128...1,508,626 JBrowse link
G Drd1 dopamine receptor D1 ISO RGD PMID:12944496 RGD:1581422 NCBI chrNW_004936609:790,647...795,187 JBrowse link
G Drd2 dopamine receptor D2 ISO RGD PMID:12944496 RGD:1581422 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
negative regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
positive regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrh growth hormone releasing hormone ISO RGD PMID:19889861, PMID:20237285 RGD:10401262, RGD:2325188 NCBI chrNW_004936561:3,946,256...3,954,472 JBrowse link
G Ghrhr growth hormone releasing hormone receptor ISO RGD PMID:20237285 RGD:10401262 NCBI chrNW_004936478:7,188,826...7,202,854 JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO (PMID:18329818) BHF-UCL PMID:18329818 NCBI chrNW_004936602:3,037,862...3,044,863 JBrowse link
G Mtnr1b melatonin receptor 1B ISO RGD PMID:19429170, PMID:22171046 RGD:9588660, RGD:9588665 NCBI chrNW_004936674:1,703,814...1,713,860 JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO RGD PMID:16378653 RGD:1642507 NCBI chrNW_004936576:1,932,526...1,939,560 JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link
positive regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrh growth hormone releasing hormone NOT ISO (PMID:15538933) BHF-UCL PMID:15538933 NCBI chrNW_004936561:3,946,256...3,954,472 JBrowse link
G Pmch pro-melanin concentrating hormone ISO RGD PMID:12964948 RGD:1642489 NCBI chrNW_004936492:11,947,489...11,948,896 JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chrNW_004936623:2,339,259...2,345,717 JBrowse link
G Uts2r urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844 NCBI chrNW_004936923:24,952...31,083 JBrowse link
positive regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor ISO in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chrNW_004936619:597,970...618,564 JBrowse link
G Opn4 opsin 4 ISO (MGI:5925970|PMID:26320947) MGI PMID:26320947 MGI:5925970 NCBI chrNW_004936804:261,210...272,449 JBrowse link
positive regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlgn1 neuroligin 1 ISO (MGI:5492265|PMID:23716671) UniProt PMID:23716671 MGI:5492265 NCBI chrNW_004936703:951,935...1,415,991 JBrowse link
G Nps neuropeptide S ISO RGD PMID:22300983 RGD:9831203 NCBI chrNW_004936486:15,172,068...15,175,568 JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:15944374 RGD:2306844 NCBI chrNW_004936623:2,339,259...2,345,717 JBrowse link
G Uts2r urotensin 2 receptor ISO RGD PMID:15944374 RGD:2306844 NCBI chrNW_004936923:24,952...31,083 JBrowse link
regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chrNW_004936580:4,165,255...4,179,285 JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 ISO (MGI:3770734|PMID:17925011) UniProt PMID:17925011 MGI:3770734 NCBI chrNW_004936704:2,007,577...2,019,520 JBrowse link
regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit ISO (MGI:3575072|PMID:15215293) MGI PMID:15215293 MGI:3575072 NCBI chrNW_004936580:4,165,255...4,179,285 JBrowse link
regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 ISO (PMID:25083013)
(MGI:6368107|PMID:25083013)
UniProt PMID:25083013 MGI:6368107 NCBI chrNW_004936486:4,400,467...4,401,588 JBrowse link
G Cort cortistatin ISO RGD PMID:8622767 RGD:727760 NCBI chrNW_004936623:4,287,175...4,289,347 JBrowse link
G Csf2 colony stimulating factor 2 ISO RGD PMID:12047622 RGD:10449529 NCBI chrNW_004936647:3,081,896...3,083,864 JBrowse link
G Drd3 dopamine receptor D3 ISO RGD PMID:15913875 RGD:1625069 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G Per3 period circadian regulator 3 ISO (PMID:17346965), (PMID:19716732), (PMID:24439663), (PMID:24577121), (PMID:26903630)
(MGI:5300112|PMID:21957163)
UniProtKB
UniProt
PMID:17346965, PMID:19716732, PMID:21957163, PMID:24439663, PMID:24577121, PMID:26903630 MGI:5300112 NCBI chrNW_004936623:2,291,211...2,362,693 JBrowse link
G Pglyrp1 peptidoglycan recognition protein 1 ISO RGD PMID:11145837 RGD:724610 NCBI chrNW_004936706:2,317,137...2,320,993 JBrowse link
G Ptgds prostaglandin D2 synthase ISO (MGI:3687807|PMID:10781097) UniProt PMID:10781097 MGI:3687807 NCBI chrNW_004936669:961,246...964,584 JBrowse link
regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hcrtr2 hypocretin receptor 2 ISO (PMID:11282968) UniProtKB PMID:11282968 NCBI chrNW_004936476:5,838,663...5,933,174 JBrowse link
G Ptger3 prostaglandin E receptor 3 ISO RGD PMID:10923657 RGD:10043386 NCBI chrNW_004936591:1,174,364...1,250,233 JBrowse link
G Ptger4 prostaglandin E receptor 4 ISO RGD PMID:10923657 RGD:10043386 NCBI chrNW_004936518:1,903,636...1,916,746 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12003
    behavior 719
      regulation of behavior 90
        regulation of circadian sleep/wake cycle 29
          regulation of circadian sleep/wake cycle, sleep + 25
          regulation of circadian sleep/wake cycle, wakefulness + 7
Path 2
Term Annotations click to browse term
  biological_process 12003
    behavior 719
      rhythmic behavior 62
        circadian behavior 60
          circadian sleep/wake cycle 37
            regulation of circadian sleep/wake cycle 29
              regulation of circadian sleep/wake cycle, sleep + 25
              regulation of circadian sleep/wake cycle, wakefulness + 7
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.