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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of circadian rhythm
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Accession:GO:0042754 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
Synonyms:exact_synonym: down regulation of circadian rhythm;   downregulation of circadian rhythm
 narrow_synonym: inhibition of circadian rhythm


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negative regulation of circadian rhythm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cipc CLOCK-interacting pacemaker ISO (MGI:MGI:5532917|PMID:17310242) RGD PMID:17310242 MGI:MGI:5532917 NCBI chr 6:110,968,014...110,990,912
Ensembl chr 6:110,968,061...110,990,912
JBrowse link
G Cry1 cryptochrome circadian regulator 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:4410413|PMID:19605937), (MGI:MGI:5532917|PMID:17310242)
UniProt
RGD
PMID:17310242, PMID:19605937 GO_REF:0000024, MGI:MGI:4410413, MGI:MGI:5532917 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cry2 cryptochrome circadian regulator 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4410413|PMID:19605937)
Ensembl
UniProt
RGD
PMID:19605937 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4410413 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Pasd1 PAS domain containing repressor 1 ISO (PMID:25936801) RGD PMID:25936801 NCBI chr16:70,001,708...70,006,009
NCBI chr16:70,011,911...70,027,313
Ensembl chr16:70,002,883...70,006,016
Ensembl chr16:70,002,883...70,006,016
JBrowse link
G Per2 period circadian regulator 2 ISO
ISS
(MGI:MGI:4410413|PMID:19605937)
GO_REF:0000024
RGD
UniProt
PMID:19605937 GO_REF:0000024, MGI:MGI:4410413 NCBI chr 9:98,555,154...98,597,362
Ensembl chr 9:98,555,169...98,597,359
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 ISO (PMID:28903391)
(MGI:MGI:6285118|PMID:28903391)
RGD PMID:28903391 MGI:MGI:6285118 NCBI chr15:52,037,693...52,116,277
Ensembl chr15:52,037,693...52,116,001
JBrowse link
G Sfpq splicing factor proline and glutamine rich ISO (MGI:MGI:5014424|PMID:21680841) RGD PMID:21680841 MGI:MGI:5014424 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sin3a SIN3 transcription regulator family member A ISO (MGI:MGI:5014424|PMID:21680841) RGD PMID:21680841 MGI:MGI:5014424 NCBI chr 8:61,748,590...61,803,314
Ensembl chr 8:61,762,768...61,803,099
JBrowse link
G Suv39h1 suppressor of variegation 3-9 homolog 1 ISO (MGI:MGI:5569417|PMID:24413057) RGD PMID:24413057 MGI:MGI:5569417 NCBI chr  X:146,532,002...146,533,538 JBrowse link
G Suv39h2 suppressor of variegation 3-9 homolog 2 ISO (MGI:MGI:5569417|PMID:24413057) RGD PMID:24413057 MGI:MGI:5569417 NCBI chr17:78,762,897...78,782,016
Ensembl chr17:78,762,991...78,782,016
JBrowse link
negative regulation of circadian sleep/wake cycle, non-REM sleep term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase IMP RGD PMID:19066225 RGD:5128864 NCBI chr 3:160,115,840...160,139,947
Ensembl chr 3:160,115,842...160,139,947
JBrowse link
G Adora1 adenosine A1 receptor IMP RGD PMID:19491711 RGD:2317916 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
negative regulation of circadian sleep/wake cycle, REM sleep term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide ISO (PMID:18329818) RGD PMID:18329818 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 IDA RGD PMID:18466985 RGD:6480669 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Ptger4 prostaglandin E receptor 4 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
negative regulation of circadian sleep/wake cycle, sleep term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA in the sleep-promoting area of the lateral preoptic area of the brain RGD PMID:16109808 RGD:1625234 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Drd1 dopamine receptor D1 IDA RGD PMID:12944496 RGD:1581422 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12944496 RGD:1581422 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
negative regulation of circadian sleep/wake cycle, wakefulness term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:10923657 RGD:10043386 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
negative regulation of locomotor rhythm term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:16982424 RGD:10412019 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of circadian rhythm 19
        negative regulation of circadian sleep/wake cycle, sleep + 7
        negative regulation of circadian sleep/wake cycle, wakefulness 1
        negative regulation of locomotor rhythm 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of biological process 13075
        regulation of circadian rhythm 134
          negative regulation of circadian rhythm 19
            negative regulation of circadian sleep/wake cycle, sleep + 7
            negative regulation of circadian sleep/wake cycle, wakefulness 1
            negative regulation of locomotor rhythm 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.