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ONTOLOGY REPORT - ANNOTATIONS


Term:GPI-anchor transamidase complex
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Accession:GO:0042765 term browser browse the term
Definition:An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxy-terminus of a precursor protein to a GPI-anchor.
Comment:Note that this term should not be confused with 'glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex ; GO:0000506', which represents a distinct complex with a different catalytic activity.
Synonyms:exact_synonym: GPIT complex


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GPI-anchor transamidase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpaa1 glycosylphosphatidylinositol anchor attachment 1 JBrowse link 7 117,394,367 117,397,950 RGD:1331364
RGD:1624291
RGD:1600115
RGD:13792537
G Pigk phosphatidylinositol glycan anchor biosynthesis, class K JBrowse link 2 257,911,099 257,997,735 RGD:1600115
RGD:1624291
RGD:13792537
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S JBrowse link 10 65,591,638 65,606,175 RGD:1624291
G Pigt phosphatidylinositol glycan anchor biosynthesis, class T JBrowse link 3 160,945,556 160,954,738 RGD:1624291
RGD:13792537
G Pigu phosphatidylinositol glycan anchor biosynthesis, class U JBrowse link 3 150,803,096 150,885,597 RGD:1600115
RGD:13792537
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      membrane protein complex 1210
        GPI-anchor transamidase complex 5
Path 2
Term Annotations click to browse term
  cellular_component 19843
    cellular anatomical entity 19457
      organelle 12557
        membrane-bounded organelle 10879
          organelle membrane 2679
            endoplasmic reticulum membrane 860
              intrinsic component of endoplasmic reticulum membrane 150
                integral component of endoplasmic reticulum membrane 142
                  GPI-anchor transamidase complex 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.