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ONTOLOGY REPORT - ANNOTATIONS


Term:glucocorticoid receptor signaling pathway
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Accession:GO:0042921 term browser browse the term
Definition:Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor.
Synonyms:exact_synonym: glucocorticoid receptor signalling pathway


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glucocorticoid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07031756.1 IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr18:32,669,427...32,670,665 JBrowse link
G Arid1a AT-rich interaction domain 1A ISO (PMID:12200431) RGD PMID:12200431 NCBI chr 5:151,904,687...151,977,973
Ensembl chr 5:151,904,684...151,977,636
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO (PMID:8649367) RGD PMID:8649367 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO MGI:MGI:1857745 (MGI:MGI:1336546|PMID:10224232), (MGI:MGI:3047515|PMID:15199138), (MGI:MGI:5616008|PMID:25510864), (MGI:MGI:74913|PMID:7628695) RGD PMID:7628695, PMID:10224232, PMID:15199138, PMID:25510864 MGI:MGI:1336546, MGI:MGI:3047515, MGI:MGI:5616008, MGI:MGI:74913 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ptges3 prostaglandin E synthase 3 ISO MGI:MGI:3701300 (MGI:MGI:3714109|PMID:17438133) RGD PMID:17438133 MGI:MGI:3714109 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta IEA
ISO
GO_REF:0000107
(PMID:15790729)
Ensembl
RGD
PMID:15790729 GO_REF:0000107 NCBI chr14:83,053,041...83,062,424
Ensembl chr14:83,053,041...83,062,424
JBrowse link
negative regulation of glucocorticoid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arntl aryl hydrocarbon receptor nuclear translocator-like IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5567887|PMID:24378737)
Ensembl
UniProt
RGD
PMID:24378737 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5567887 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Clock clock circadian regulator IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5567887|PMID:24378737)
Ensembl
UniProt
RGD
PMID:24378737 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5567887 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Cry1 cryptochrome circadian regulator 1 ISS
ISO
GO_REF:0000024
UniProtKB:P97784 (MGI:MGI:5302136|PMID:22170608), (MGI:MGI:5567887|PMID:24378737)
UniProt
RGD
PMID:22170608, PMID:24378737 GO_REF:0000024, MGI:MGI:5302136, MGI:MGI:5567887 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cry2 cryptochrome circadian regulator 2 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
UniProtKB:P97784 (MGI:MGI:5302136|PMID:22170608)
Ensembl
UniProt
RGD
PMID:22170608 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5302136 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Per1 period circadian regulator 1 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5567887|PMID:24378737)
Ensembl
UniProt
RGD
PMID:24378737 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5567887 NCBI chr10:55,681,761...55,696,557
Ensembl chr10:55,687,050...55,695,994
JBrowse link
G Phb prohibitin ISO (PMID:16964284) RGD PMID:16964284 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
positive regulation of glucocorticoid receptor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IDA PMID:23878391 MGI PMID:23878391 RGD:10047172 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Lmo3 LIM domain only 3 ISO (PMID:23823477) RGD PMID:23823477 NCBI chr 4:172,942,023...173,005,630
Ensembl chr 4:172,942,020...173,005,634
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 IMP RGD PMID:17481888 RGD:5688226 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IDA RGD PMID:22001115 RGD:5686284 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IGI PMID:23878391 MGI PMID:23878391 RGD:10047172 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit IMP RGD PMID:8943293 RGD:8694070 NCBI chr 1:78,944,054...78,968,361
Ensembl chr 1:78,944,040...78,968,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      signal transduction 7011
        intracellular receptor signaling pathway 255
          intracellular steroid hormone receptor signaling pathway 113
            corticosteroid receptor signaling pathway 18
              glucocorticoid receptor signaling pathway 17
                negative regulation of glucocorticoid receptor signaling pathway 6
                positive regulation of glucocorticoid receptor signaling pathway 6
                regulation of glucocorticoid receptor signaling pathway + 12
Path 2
Term Annotations click to browse term
  biological_process 20027
    response to stimulus 10583
      cellular response to stimulus 8920
        cellular response to chemical stimulus 3528
          cellular response to organic substance 2845
            cellular response to hormone stimulus 758
              hormone-mediated signaling pathway 186
                steroid hormone mediated signaling pathway 132
                  intracellular steroid hormone receptor signaling pathway 113
                    corticosteroid receptor signaling pathway 18
                      glucocorticoid receptor signaling pathway 17
                        negative regulation of glucocorticoid receptor signaling pathway 6
                        positive regulation of glucocorticoid receptor signaling pathway 6
                        regulation of glucocorticoid receptor signaling pathway + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.