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ONTOLOGY REPORT - ANNOTATIONS


Term:activation of Janus kinase activity
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Accession:GO:0042976 term browser browse the term
Definition:The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
Synonyms:exact_synonym: activation of JAK protein;   activation of JAK protein by tyrosine phosphorylation
 narrow_synonym: activation of JAK1 kinase activity;   activation of JAK1 protein;   activation of JAK2 kinase activity;   activation of JAK2 protein;   tyrosine phosphorylation of JAK1 protein;   tyrosine phosphorylation of JAK2 protein
 broad_synonym: positive regulation of JAK protein activity by tyrosine phosphorylation
 related_synonym: tyrosine phosphorylation of JAK protein
 alt_id: GO:0010531;   GO:0042977


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activation of Janus kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:6478796
G Ghr growth hormone receptor JBrowse link 2 53,149,225 53,413,954 RGD:1624962
RGD:8553732
G Il3 interleukin 3 JBrowse link 10 39,620,535 39,622,973 RGD:1624291
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:1624291
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
RGD:1600115
G Pibf1 progesterone immunomodulatory binding factor 1 JBrowse link 15 83,494,110 83,663,202 RGD:1624291
RGD:1600115
G Prl3d4 prolactin family 3, subfamily d, member 4 JBrowse link 17 39,271,883 39,278,716 RGD:1298822
G Ptk2b protein tyrosine kinase 2 beta JBrowse link 15 42,827,306 42,947,796 RGD:633057
RGD:1624291
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd300a Cd300a molecule JBrowse link 10 103,437,978 103,451,170 RGD:1624291
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:1625011
positive regulation of activation of Janus kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:1624291
RGD:1600115
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:1624291
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1624291
RGD:1600115
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:1624291
RGD:13792537
G Il6r interleukin 6 receptor JBrowse link 2 189,196,180 189,255,987 RGD:1624291
RGD:13792537
regulation of activation of Janus kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    cellular process 16266
      signal transduction 6597
        positive regulation of signal transduction 1596
          positive regulation of receptor signaling pathway via STAT 110
            positive regulation of receptor signaling pathway via JAK-STAT 106
              activation of Janus kinase activity 16
                negative regulation of activation of Janus kinase activity 2
                positive regulation of activation of Janus kinase activity 5
                regulation of activation of Janus kinase activity + 8
Path 2
Term Annotations click to browse term
  biological_process 18166
    biological regulation 12793
      regulation of biological process 12128
        regulation of metabolic process 6259
          regulation of cellular metabolic process 5755
            regulation of phosphorus metabolic process 1800
              regulation of phosphate metabolic process 1799
                regulation of phosphorylation 1606
                  regulation of kinase activity 822
                    regulation of protein kinase activity 741
                      positive regulation of protein kinase activity 488
                        activation of protein kinase activity 279
                          activation of Janus kinase activity 16
                            negative regulation of activation of Janus kinase activity 2
                            positive regulation of activation of Janus kinase activity 5
                            regulation of activation of Janus kinase activity + 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.