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ONTOLOGY REPORT - ANNOTATIONS


Term:T cell homeostasis
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Accession:GO:0043029 term browser browse the term
Definition:The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
Comment:Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus.
Synonyms:exact_synonym: T lymphocyte homeostasis


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T cell homeostasis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:1624291
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Cacna1f calcium voltage-gated channel subunit alpha1 F JBrowse link X 15,712,709 15,741,135 RGD:1600115
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:1624291
G Chst3 carbohydrate sulfotransferase 3 JBrowse link 20 29,731,828 29,768,656 RGD:1624291
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:1624291
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Foxn1 forkhead box N1 JBrowse link 10 65,621,142 65,634,666 RGD:1624291
G Gimap5 GTPase, IMAP family member 5 JBrowse link 4 78,377,228 78,386,683 RGD:1303374
G Gpr174 G protein-coupled receptor 174 JBrowse link X 78,358,347 78,399,944 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Jak3 Janus kinase 3 JBrowse link 16 20,107,471 20,120,678 RGD:1624291
RGD:13792537
RGD:1600115
G Nckap1l NCK associated protein 1 like JBrowse link 7 145,068,239 145,113,507 RGD:1624291
RGD:1600115
G P2rx7 purinergic receptor P2X 7 JBrowse link 12 39,353,613 39,396,042 RGD:1624291
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma JBrowse link 6 76,056,585 76,079,755 RGD:1624291
RGD:13792537
G Ppp3cb protein phosphatase 3 catalytic subunit beta JBrowse link 15 4,209,702 4,236,895 RGD:1624291
RGD:1600115
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
G Rc3h1 ring finger and CCCH-type domains 1 JBrowse link 13 78,723,028 78,794,663 RGD:1624291
G Rc3h2 ring finger and CCCH-type domains 2 JBrowse link 3 21,621,976 21,676,789 RGD:1624291
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
G Sit1 signaling threshold regulating transmembrane adaptor 1 JBrowse link 5 58,985,912 58,987,538 RGD:1600115
G Slc39a3 solute carrier family 39 member 3 JBrowse link 7 11,545,073 11,551,074 RGD:1624291
G Slc46a2 solute carrier family 46, member 2 JBrowse link 5 77,165,463 77,174,177 RGD:1624291
G Spns2 sphingolipid transporter 2 JBrowse link 10 59,010,428 59,049,482 RGD:1624291
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:1624291
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:1624291
RGD:1600115
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 JBrowse link 1 219,126,687 219,139,466 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1624291
G Zc3h8 zinc finger CCCH type containing 8 JBrowse link 3 121,471,836 121,488,528 RGD:1624291
activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Rps6 ribosomal protein S6 JBrowse link 5 105,197,821 105,200,681 RGD:1624291
G Siva1 SIVA1, apoptosis-inducing factor JBrowse link 6 137,209,999 137,214,379 RGD:1624291
negative regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fadd Fas associated via death domain JBrowse link 1 217,746,176 217,748,581 RGD:1624291
RGD:1600115
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial JBrowse link 1 275,843,823 275,906,880 RGD:1624291
RGD:1600115
G Tnfrsf4 TNF receptor superfamily member 4 JBrowse link 5 173,447,784 173,450,474 RGD:1624291
G Tsc22d3 TSC22 domain family, member 3 JBrowse link X 111,884,285 111,944,693 RGD:1624291
negative regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
positive regulation of activated T cell autonomous cell death term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
positive regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1624291
positive regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd24 CD24 molecule JBrowse link 20 48,335,540 48,340,847 RGD:1624291
regulation of activation-induced cell death of T cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 15 34,470,796 34,479,741 RGD:1624291
RGD:1600115
regulation of T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:1624291
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:1624291
G Lmo1 LIM domain only 1 JBrowse link 1 173,728,183 173,764,288 RGD:1624291
RGD:1600115
T cell homeostatic proliferation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19335
    immune system process 2640
      leukocyte homeostasis 111
        lymphocyte homeostasis 78
          T cell homeostasis 47
            T cell homeostatic proliferation + 5
            activated T cell autonomous cell death + 1
            activation-induced cell death of T cells + 13
Path 2
Term Annotations click to browse term
  biological_process 19335
    biological regulation 13337
      regulation of biological quality 4238
        homeostatic process 2019
          homeostasis of number of cells 319
            leukocyte homeostasis 111
              lymphocyte homeostasis 78
                T cell homeostasis 47
                  T cell homeostatic proliferation + 5
                  activated T cell autonomous cell death + 1
                  activation-induced cell death of T cells + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.