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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
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Accession:GO:0043154 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
Synonyms:exact_synonym: down regulation of caspase activity;   downregulation of caspase activity;   negative regulation of caspase activation
 narrow_synonym: inhibition of caspase activation;   inhibition of caspase activity
 broad_synonym: negative regulation of caspase activity
 alt_id: GO:0001719


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negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07029605.1 RGD:1600115
G AC135826.1 RGD:1600115
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:1625666
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
RGD:1600115
G Akt2 AKT serine/threonine kinase 2 JBrowse link 1 84,400,939 84,451,223 RGD:2313324
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1624291
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 JBrowse link 1 187,770,160 187,779,675 RGD:1624291
RGD:1600115
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:1600115
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:5510006
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:1624291
RGD:1600115
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1600115
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:13792537
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:13792537
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:1600115
RGD:1624291
G Birc7 baculoviral IAP repeat-containing 7 JBrowse link 3 176,438,335 176,443,864 RGD:13792537
G Cd27 CD27 molecule JBrowse link 4 157,744,881 157,751,609 RGD:1600115
G Cd44 CD44 molecule (Indian blood group) JBrowse link 3 92,695,083 92,783,820 RGD:1600115
RGD:1624291
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:1624291
RGD:1600115
G Cryaa crystallin, alpha A JBrowse link 20 10,438,444 10,442,189 RGD:1624291
RGD:1600115
G Cryab crystallin, alpha B JBrowse link 8 55,178,543 55,182,546 RGD:1624291
RGD:1600115
G Csnk2a1 casein kinase 2 alpha 1 JBrowse link 3 147,713,808 147,760,375 RGD:1624291
RGD:1600115
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
RGD:1600115
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:1624291
RGD:1600115
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 JBrowse link 4 2,711,329 2,774,969 RGD:1624291
G Dpep1 dipeptidase 1 JBrowse link 19 55,973,447 55,998,830 RGD:1624291
RGD:1600115
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:7327216
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1624291
RGD:1600115
G Fnip1 folliculin interacting protein 1 JBrowse link 10 39,786,687 39,870,188 RGD:1624291
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:1624291
RGD:1600115
G Gpi glucose-6-phosphate isomerase JBrowse link 1 90,063,411 90,091,287 RGD:1600634
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1624291
RGD:1600115
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304324
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:1624291
RGD:1600115
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1626654
RGD:1624291
G Igbp1 immunoglobulin binding protein 1 JBrowse link X 70,322,764 70,345,005 RGD:1624291
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:1600072
G Il24 interleukin 24 JBrowse link 13 47,618,451 47,623,849 RGD:1624291
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:2306937
G Ints1 integrator complex subunit 1 JBrowse link 12 16,950,704 16,974,896 RGD:1624291
G Klf4 Kruppel like factor 4 JBrowse link 5 72,283,311 72,287,669 RGD:1624291
RGD:1600115
G Lamp3 lysosomal-associated membrane protein 3 JBrowse link 11 84,930,965 85,000,694 RGD:1624291
G Lamtor5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 JBrowse link 2 210,034,095 210,039,451 RGD:1624291
RGD:1600115
G Lef1 lymphoid enhancer binding factor 1 JBrowse link 2 236,232,115 236,345,061 RGD:1600115
RGD:13792537
RGD:1624291
G Map2k5 mitogen activated protein kinase kinase 5 JBrowse link 8 68,055,976 68,282,656 RGD:8553940
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:2317361
G Mical1 microtubule associated monooxygenase, calponin and LIM domain containing 1 JBrowse link 20 46,199,981 46,211,930 RGD:1624291
RGD:1600115
G Mir494 microRNA 494 JBrowse link 6 133,864,370 133,864,452 RGD:1624291
G Mrtfa myocardin related transcription factor A JBrowse link 7 122,233,196 122,403,661 RGD:1624291
RGD:1600115
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:1600115
G Naip6 NLR family, apoptosis inhibitory protein 6 JBrowse link 2 30,377,505 30,418,578 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:8553292
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 7 142,899,358 142,920,216 RGD:1624291
RGD:1600115
G Pax2 paired box 2 JBrowse link 1 264,493,579 264,585,073 RGD:1600115
RGD:1624291
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:2316785
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:1600115
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1600115
G Ptger2 prostaglandin E receptor 2 JBrowse link 15 19,336,029 19,349,759 RGD:1624291
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1624291
RGD:1600115
G Ptma prothymosin alpha JBrowse link 9 93,545,396 93,549,436 RGD:734494
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:1624291
RGD:1600115
G Rps6ka1 ribosomal protein S6 kinase A1 JBrowse link 5 152,078,217 152,122,684 RGD:1600115
RGD:1624291
G Rps6ka3 ribosomal protein S6 kinase A3 JBrowse link X 37,469,736 37,576,055 RGD:1624291
RGD:1600115
G Serpinb9 serpin family B member 9 JBrowse link 17 32,648,846 32,673,047 RGD:1600115
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:1624291
G Sfrp2 secreted frizzled-related protein 2 JBrowse link 2 182,723,732 182,731,277 RGD:1624291
RGD:1600115
G Sh3rf1 SH3 domain containing ring finger 1 JBrowse link 16 32,062,425 32,227,526 RGD:1624291
RGD:1600115
G Siah2 siah E3 ubiquitin protein ligase 2 JBrowse link 2 148,874,151 148,891,900 RGD:1624291
RGD:1600115
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
RGD:1600115
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
RGD:1600115
G Tfap2b transcription factor AP-2 beta JBrowse link 9 25,410,669 25,440,568 RGD:1600115
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1624291
RGD:1600115
G Tnfaip8 TNF alpha induced protein 8 JBrowse link 18 44,664,310 44,779,914 RGD:1600115
G Tnfsf14 TNF superfamily member 14 JBrowse link 9 9,761,363 9,765,461 RGD:1600115
G Triap1 TP53 regulated inhibitor of apoptosis 1 JBrowse link 12 46,987,404 46,989,906 RGD:1624291
G Usp47 ubiquitin specific peptidase 47 JBrowse link 1 176,854,589 176,937,763 RGD:1624291
RGD:1600115
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:1624291
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1600115
G Wnt9a Wnt family member 9A JBrowse link 10 45,659,045 45,686,103 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:13792537
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l12 BCL2 like 12 JBrowse link 1 100,984,550 100,993,269 RGD:1624291
RGD:1600115
G Birc2 baculoviral IAP repeat-containing 2 JBrowse link 8 6,014,014 6,036,668 RGD:13792537
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 8 6,048,590 6,076,828 RGD:13792537
G Birc7 baculoviral IAP repeat-containing 7 JBrowse link 3 176,438,335 176,443,864 RGD:13792537
G Fcmr Fc fragment of IgM receptor JBrowse link 13 47,602,701 47,617,065 RGD:1624291
G Nol3 nucleolar protein 3 JBrowse link 19 37,232,567 37,236,668 RGD:1624291
G Xiap X-linked inhibitor of apoptosis JBrowse link X 128,409,425 128,455,786 RGD:1624291
RGD:13792537
RGD:1600115
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Caap1 caspase activity and apoptosis inhibitor 1 JBrowse link 5 113,479,416 113,532,961 RGD:1624291
RGD:13792537
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:1624291
RGD:1600115
G Nle1 notchless homolog 1 JBrowse link 10 70,250,959 70,261,880 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pih1d1 PIH1 domain containing 1 JBrowse link 1 101,151,240 101,156,806 RGD:1624291
RGD:1600115
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:1624291
RGD:1600115
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G LOC100910732 serine/threonine-protein kinase PAK 2-like JBrowse link 11 71,959,058 72,021,252 RGD:13792537
G Pak2 p21 (RAC1) activated kinase 2 JBrowse link 11 72,829,407 72,865,815 RGD:1624291
RGD:13792537
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase JBrowse link 10 70,157,621 70,220,618 RGD:1624291
RGD:1600115
G Rnf34 ring finger protein 34 JBrowse link 12 39,164,290 39,185,209 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19317
    cellular process 17226
      cell death 2145
        programmed cell death 1967
          negative regulation of programmed cell death 989
            negative regulation of apoptotic process 968
              negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 92
                inhibition of cysteine-type endopeptidase activity involved in apoptotic process 7
                negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 6
                negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 4
Path 2
Term Annotations click to browse term
  biological_process 19317
    metabolic process 11540
      organic substance metabolic process 10932
        macromolecule metabolic process 9412
          protein metabolic process 5975
            cellular protein metabolic process 5303
              regulation of cellular protein metabolic process 2745
                negative regulation of cellular protein metabolic process 1111
                  negative regulation of proteolysis 404
                    negative regulation of peptidase activity 301
                      negative regulation of endopeptidase activity 282
                        negative regulation of cysteine-type endopeptidase activity 100
                          negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 92
                            inhibition of cysteine-type endopeptidase activity involved in apoptotic process 7
                            negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 6
                            negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.