Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine
go back to main search page
Accession:GO:0043197 term browser browse the term
Definition:A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including 'thin', 'stubby', 'mushroom', and 'branched', with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
Synonyms:exact_synonym: dendrite spine
 narrow_synonym: branched dendritic spine;   mushroom dendritic spine;   sessile dendritic spine;   stubby dendritic spine;   thin dendritic spine
 xref: NIF_Subcellular:sao1799103720;   Wikipedia:Dendritic_spine


show annotations for term's descendants       view all columns           Sort by:
 
dendritic spine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADORA1 adenosine A1 receptor JBrowse link 9 113,835,279 113,875,899 RGD:14298760
G AKAP5 A-kinase anchoring protein 5 JBrowse link 7 88,538,938 88,544,330 RGD:14298760
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 JBrowse link 15 105,328,717 105,401,152 RGD:14298760
G APBA1 amyloid beta precursor protein binding family A member 1 JBrowse link 1 222,758,508 222,990,000 RGD:14298760
G APBA2 amyloid beta precursor protein binding family A member 2 JBrowse link 1 144,183,148 144,315,154 RGD:14298760
G APBA3 amyloid beta precursor protein binding family A member 3 JBrowse link 2 74,930,077 74,945,372 RGD:14298760
G APP amyloid beta precursor protein JBrowse link 13 189,434,854 189,716,120 RGD:14298760
G ARC activity regulated cytoskeleton associated protein JBrowse link 4 1,517,986 1,521,403 RGD:14298760
G ARF4 ADP ribosylation factor 4 JBrowse link 13 39,410,094 39,430,177 RGD:14298760
G ARHGAP44 Rho GTPase activating protein 44 JBrowse link 12 57,049,900 57,206,706 RGD:14298760
G ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 JBrowse link 4 10,103,860 10,451,928 RGD:14298760
G ASIC2 acid sensing ion channel subunit 2 JBrowse link 12 41,726,987 42,031,997 RGD:14298760
G CALB1 calbindin 1 JBrowse link 4 46,701,276 46,723,548 RGD:14298760
G CAMK2A calcium/calmodulin dependent protein kinase II alpha JBrowse link 2 151,248,356 151,353,907 RGD:14298760
G CDC42 cell division cycle 42 JBrowse link 6 80,035,034 80,089,243 RGD:14298760
G DGKI diacylglycerol kinase iota JBrowse link 18 11,705,055 12,187,098 RGD:14298760
G DNM1 dynamin 1 JBrowse link 1 268,653,045 268,702,233 RGD:14298760
G DNM2 dynamin 2 JBrowse link 2 69,474,011 69,574,427 RGD:14298760
G DNM3 dynamin 3 JBrowse link 9 114,262,782 114,805,252 RGD:14298760
G DRD1 dopamine receptor D1 JBrowse link 16 49,189,555 49,193,722 RGD:14298760
G DTNBP1 dystrobrevin binding protein 1 JBrowse link 7 11,602,470 11,720,156 RGD:14298760
G EPHA1 EPH receptor A1 JBrowse link 18 6,843,305 6,860,976 RGD:14298760
G EPHA4 EPH receptor A4 JBrowse link 15 123,350,867 123,501,872 RGD:14298760
G FBXO2 F-box protein 2 JBrowse link 6 71,740,647 71,747,265 RGD:14298760
G FMR1 FMRP translational regulator 1 JBrowse link X 120,361,232 120,400,282 RGD:14298760
G FRMPD4 FERM and PDZ domain containing 4 JBrowse link X 8,625,039 9,451,433 RGD:14298760
G FXR1 FMR1 autosomal homolog 1 JBrowse link 13 118,839,314 118,899,804 RGD:14298760
G FXR2 FMR1 autosomal homolog 2 JBrowse link 12 52,885,932 52,903,257 RGD:14298760
G GRID2 glutamate ionotropic receptor delta type subunit 2 JBrowse link 8 125,821,195 127,130,617 RGD:14298760
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 RGD:14298760
G GRM3 glutamate metabotropic receptor 3 JBrowse link 9 93,731,210 93,974,718 RGD:14298760
G ITGB1 integrin subunit beta 1 JBrowse link 10 56,078,393 56,130,608 RGD:14298760
G KCNA4 potassium voltage-gated channel subfamily A member 4 JBrowse link 2 30,605,503 30,615,997 RGD:14298760
G KCND2 potassium voltage-gated channel subfamily D member 2 JBrowse link 18 26,139,457 26,624,210 RGD:14298760
G KCNN1 potassium calcium-activated channel subfamily N member 1 JBrowse link 2 59,780,010 59,814,815 RGD:14298760
G KCNN2 potassium calcium-activated channel subfamily N member 2 JBrowse link 2 118,439,328 118,882,299 RGD:14298760
G LRRC4 leucine rich repeat containing 4 JBrowse link 18 20,319,317 20,322,875 RGD:14298760
G MPP2 membrane palmitoylated protein 2 JBrowse link 12 19,239,557 19,268,013 RGD:14298760
G MX1 MX dynamin like GTPase 1 JBrowse link 13 204,843,049 204,868,927 RGD:14298760
G MX2 myxovirus (influenza virus) resistance 2 (mouse) JBrowse link 13 204,798,633 204,821,612 RGD:14298760
G NEDD4 NEDD4 E3 ubiquitin protein ligase JBrowse link 1 115,941,945 116,069,884 RGD:14298760
G NEURL1 neuralized E3 ubiquitin protein ligase 1 JBrowse link 14 114,436,887 114,515,713 RGD:14298760
G NR1D1 nuclear receptor subfamily 1 group D member 1 JBrowse link 12 22,263,549 22,274,131 RGD:14298760
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 10 30,030,050 30,429,938 RGD:14298760
G OPHN1 oligophrenin 1 JBrowse link X 54,056,504 54,617,045 RGD:14298760
G PALM paralemmin JBrowse link 2 77,619,199 77,644,561 RGD:14298760
G PALMD palmdelphin JBrowse link 4 118,377,246 118,427,800 RGD:14298760
G PPP1R9A protein phosphatase 1 regulatory subunit 9A JBrowse link 9 74,635,285 74,944,050 RGD:14298760
G PPP3CA protein phosphatase 3 catalytic subunit alpha JBrowse link 8 119,429,181 119,754,615 RGD:14298760
G PRKACA protein kinase cAMP-activated catalytic subunit alpha JBrowse link 2 65,074,876 65,095,564 RGD:14298760
G PRKAR2B protein kinase cAMP-dependent type II regulatory subunit beta JBrowse link 9 106,851,044 106,957,519 RGD:14298760
G PSD pleckstrin and Sec7 domain containing JBrowse link 14 113,414,697 113,430,093 RGD:14298760
G PSMC2 proteasome 26S subunit, ATPase 2 JBrowse link 9 103,362,684 103,376,048 RGD:14298760
G PTK2B protein tyrosine kinase 2 beta JBrowse link 14 11,063,662 11,194,196 RGD:14298760
G PTPRO protein tyrosine phosphatase receptor type O JBrowse link 5 57,021,819 57,263,395 RGD:14298760
G RAB8A RAB8A, member RAS oncogene family JBrowse link 2 61,430,680 61,450,351 RGD:14298760
G RAC1 Rac family small GTPase 1 JBrowse link 3 4,781,776 4,803,510 RGD:14298760
G RGS14 regulator of G protein signaling 14 JBrowse link 2 80,574,411 80,589,998 RGD:14298760
G RHOA ras homolog family member A JBrowse link 13 31,918,484 31,991,207 RGD:14298760
G SEZ6 seizure related 6 homolog JBrowse link 12 45,178,292 45,223,829 RGD:14298760
G SHANK2 SH3 and multiple ankyrin repeat domains 2 JBrowse link 2 2,517,853 3,016,959 RGD:14298760
G SHANK3 SH3 and multiple ankyrin repeat domains 3 JBrowse link 5 41,376 93,033 RGD:14298760
G STX4 syntaxin 4 JBrowse link 3 17,422,266 17,431,377 RGD:14298760
G USP50 ubiquitin specific peptidase 50 JBrowse link 1 121,272,977 121,307,029 RGD:14298760
G USP8 ubiquitin specific peptidase 8 JBrowse link 1 121,306,031 121,376,154 RGD:14298760
G ZNF804A zinc finger protein 804A JBrowse link 15 89,842,424 90,150,352 RGD:14298760
dendritic spine head term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DNM1 dynamin 1 JBrowse link 1 268,653,045 268,702,233 RGD:14298760
G DNM2 dynamin 2 JBrowse link 2 69,474,011 69,574,427 RGD:14298760
G DNM3 dynamin 3 JBrowse link 9 114,262,782 114,805,252 RGD:14298760
G MX1 MX dynamin like GTPase 1 JBrowse link 13 204,843,049 204,868,927 RGD:14298760
G MX2 myxovirus (influenza virus) resistance 2 (mouse) JBrowse link 13 204,798,633 204,821,612 RGD:14298760
dendritic spine neck term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FMR1 FMRP translational regulator 1 JBrowse link X 120,361,232 120,400,282 RGD:14298760
G FXR1 FMR1 autosomal homolog 1 JBrowse link 13 118,839,314 118,899,804 RGD:14298760
G FXR2 FMR1 autosomal homolog 2 JBrowse link 12 52,885,932 52,903,257 RGD:14298760
spine apparatus term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G SYNPO synaptopodin JBrowse link 2 151,571,264 151,634,103 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 15603
    cellular anatomical entity 15450
      postsynapse 341
        dendritic spine 67
          cytoskeleton of dendritic spine + 0
          dendritic spine cytoplasm 0
          dendritic spine head 5
          dendritic spine neck + 3
          spine apparatus + 1
          thorny excrescence 0
Path 2
Term Annotations click to browse term
  cellular_component 15603
    cellular anatomical entity 15450
      cell projection 1304
        plasma membrane bounded cell projection 1281
          neuron projection 731
            dendritic tree 288
              dendrite 288
                dendritic spine 67
                  cytoskeleton of dendritic spine + 0
                  dendritic spine cytoplasm 0
                  dendritic spine head 5
                  dendritic spine neck + 3
                  spine apparatus + 1
                  thorny excrescence 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.