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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
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Accession:GO:0043280 term browser browse the term
Definition:Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
Synonyms:exact_synonym: up regulation of caspase activity;   upregulation of caspase activity
 narrow_synonym: activation of caspase activity;   stimulation of caspase activity
 broad_synonym: positive regulation of caspase activity


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positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acvr1c activin A receptor type 1C JBrowse link 3 44,272,859 44,342,501 RGD:1624291
RGD:1600115
G Alox12 arachidonate 12-lipoxygenase, 12S type JBrowse link 10 56,851,734 56,864,049 RGD:2313858
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 JBrowse link 4 129,574,363 129,598,240 RGD:1600115
RGD:1624291
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:5510006
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
RGD:1600115
G Bcl10 BCL10, immune signaling adaptor JBrowse link 2 251,805,392 251,814,957 RGD:1624291
RGD:1600115
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
RGD:1600115
G Card9 caspase recruitment domain family, member 9 JBrowse link 3 3,798,346 3,806,841 RGD:1624291
RGD:1600115
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:1624291
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:2311464
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:1624291
RGD:1600115
G Ccn2 cellular communication network factor 2 JBrowse link 1 21,851,657 21,854,773 RGD:2314487
G Clec7a C-type lectin domain containing 7A JBrowse link 4 163,216,152 163,227,367 RGD:1624291
RGD:1600115
G Coa8 cytochrome c oxidase assembly factor 8 JBrowse link 6
6
136,185,772
136,279,476
136,210,936
136,304,317
RGD:1624291
RGD:13792537
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:1624291
G Dapk1 death associated protein kinase 1 JBrowse link 17 4,297,038 4,454,941 RGD:1624291
RGD:1600115
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
RGD:1600115
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:8662904
G Fis1 fission, mitochondrial 1 JBrowse link 12 22,750,485 22,765,324 RGD:1624291
RGD:1600115
G Foxl2 forkhead box L2 JBrowse link 8 107,194,492 107,197,644 RGD:1624291
RGD:1600115
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:8553942
G Gramd4 GRAM domain containing 4 JBrowse link 7 126,939,819 127,013,455 RGD:1624291
RGD:1600115
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:1624291
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:10403035
G Htra2 HtrA serine peptidase 2 JBrowse link 4 113,883,671 113,886,833 RGD:1624291
G Il24 interleukin 24 JBrowse link 13 47,618,451 47,623,849 RGD:1624291
G Malt1 MALT1 paracaspase JBrowse link 18 61,108,712 61,162,446 RGD:1624291
RGD:1600115
G Map3k5 mitogen-activated protein kinase kinase kinase 5 JBrowse link 1 15,412,603 15,613,752 RGD:1624291
RGD:1600115
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:2304239
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:1624291
G Mtch2 mitochondrial carrier 2 JBrowse link 3 79,678,141 79,695,356 RGD:1624291
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
RGD:1600115
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 JBrowse link 16 21,275,311 21,282,246 RGD:1624291
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1624291
RGD:1600115
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:13792537
G Nlrp1b NLR family, pyrin domain containing 1B JBrowse link 10 57,755,957 57,847,867 RGD:1624291
G Nlrp2 NLR family pyrin domain containing 2 JBrowse link 1 73,082,648 73,121,118 RGD:1624291
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
RGD:13792537
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
G Nodal nodal growth differentiation factor JBrowse link 20 31,035,729 31,044,096 RGD:1624291
RGD:1600115
G Pdcd5 programmed cell death 5 JBrowse link 1 91,173,473 91,178,801 RGD:1624291
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F JBrowse link 11 88,313,709 88,343,726 RGD:8553939
RGD:13792537
RGD:1624291
G Ppp2ca protein phosphatase 2 catalytic subunit alpha JBrowse link 10 37,534,449 37,554,861 RGD:8693423
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:5491174
RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:1600115
RGD:1624291
G Rhoa ras homolog family member A JBrowse link 8 117,082,440 117,116,244 RGD:1642961
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:1624291
G Sox7 SRY-box transcription factor 7 JBrowse link 15 47,293,699 47,300,460 RGD:1624291
RGD:1600115
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1624291
RGD:1600115
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Tnfsf10 TNF superfamily member 10 JBrowse link 2 113,008,008 113,026,899 RGD:1624291
RGD:1600115
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats JBrowse link 8 65,686,586 65,774,940 RGD:1624291
G Wdr35 WD repeat domain 35 JBrowse link 6 34,094,291 34,152,048 RGD:11553917
G Wnt3a Wnt family member 3A JBrowse link 10 45,598,898 45,643,151 RGD:1624291
RGD:1600115
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acer2 alkaline ceramidase 2 JBrowse link 5 105,230,540 105,279,732 RGD:1624291
RGD:1600115
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:1624291
RGD:1600115
G Anp32b acidic nuclear phosphoprotein 32 family member B JBrowse link 5 62,070,709 62,094,633 RGD:1600115
RGD:1624291
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 JBrowse link 10 59,528,849 59,560,440 RGD:1624291
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:1624291
RGD:1600115
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1600115
RGD:1624291
G Bbc3 Bcl-2 binding component 3 JBrowse link 1 78,261,491 78,267,802 RGD:1624291
RGD:13792537
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:1624291
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:1624291
RGD:13792537
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:13792537
G Casp12 caspase 12 JBrowse link 8 2,658,892 2,686,160 RGD:13792537
G Casp14 caspase 14 JBrowse link 7 13,938,376 13,944,286 RGD:13792537
G Casp4 caspase 4 JBrowse link 8 2,616,391 2,651,682 RGD:632459
RGD:13792537
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:1624291
RGD:13792537
G Casp8ap2 caspase 8 associated protein 2 JBrowse link 5 47,853,699 47,891,147 RGD:1624291
RGD:13792537
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:1624291
RGD:13792537
G Cck cholecystokinin JBrowse link 8 130,120,525 130,127,515 RGD:625521
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 9 65,534,608 65,586,395 RGD:13792537
G Col4a3 collagen type IV alpha 3 chain JBrowse link 9 88,357,528 88,484,735 RGD:1624291
RGD:1600115
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 7 36,395,665 36,408,588 RGD:1624291
RGD:13792537
G Ctsh cathepsin H JBrowse link 8 97,439,155 97,458,293 RGD:1600115
G Dap death-associated protein JBrowse link 2 84,275,884 84,328,998 RGD:1624291
G Diablo diablo, IAP-binding mitochondrial protein JBrowse link 12 38,490,230 38,503,344 RGD:1624291
G Dlc1 DLC1 Rho GTPase activating protein JBrowse link 16 58,776,489 59,247,752 RGD:1600115
RGD:1624291
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 JBrowse link 10 11,059,701 11,085,186 RGD:1624291
G Egln3 egl-9 family hypoxia-inducible factor 3 JBrowse link 6 75,050,329 75,075,795 RGD:1600115
RGD:1624291
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 JBrowse link 4 98,648,513 98,709,695 RGD:1624291
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:1624291
RGD:1600115
G Fam162a family with sequence similarity 162, member A JBrowse link 11 67,618,683 67,646,253 RGD:1624291
RGD:1600115
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:1624291
RGD:1600115
G Hip1 huntingtin interacting protein 1 JBrowse link 12 24,180,795 24,315,373 RGD:1624291
RGD:13792537
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1624291
RGD:13792537
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:1624291
G Ift57 intraflagellar transport 57 JBrowse link 11 53,664,638 53,731,779 RGD:1624291
RGD:1600115
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Khdc1 KH domain containing 1 JBrowse link 9 27,546,069 27,547,769 RGD:13792537
G Khdc1b KH domain containing 1B JBrowse link 9 27,554,436 27,556,770 RGD:1624291
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:1624291
RGD:1600115
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:1600115
G Mtch1 mitochondrial carrier 1 JBrowse link 20 6,937,341 6,961,165 RGD:1624291
RGD:1600115
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 JBrowse link 5 156,855,105 156,864,517 RGD:1624291
RGD:1600115
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:1624291
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:1624291
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:1600115
RGD:1624291
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1600115
RGD:1624291
G Nlrc4 NLR family, CARD domain containing 4 JBrowse link 6 22,167,874 22,194,755 RGD:1624291
RGD:1600115
G Nlrp1a NLR family, pyrin domain containing 1A JBrowse link 10 57,692,474 57,747,608 RGD:1624291
RGD:13792537
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:1624291
RGD:1600115
G Nod1 nucleotide-binding oligomerization domain containing 1 JBrowse link 4 85,123,965 85,175,206 RGD:1624291
RGD:1600115
G P2rx1 purinergic receptor P2X 1 JBrowse link 10 59,566,268 59,581,328 RGD:1624291
RGD:1600115
G Pdcd2 programmed cell death 2 JBrowse link 1 57,512,968 57,518,458 RGD:1624291
RGD:1600115
G Pdcd6 programmed cell death 6 JBrowse link 1 31,576,183 31,591,852 RGD:1624291
RGD:1600115
G Pidd1 p53-induced death domain protein 1 JBrowse link 1 214,418,751 214,423,959 RGD:1624291
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 JBrowse link 18 62,159,128 62,179,635 RGD:1624291
RGD:1600115
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
RGD:1600115
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:1624291
RGD:1600115
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:1624291
RGD:1600115
G Rack1 receptor for activated C kinase 1 JBrowse link 10 34,149,717 34,155,198 RGD:1624291
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:1624291
G Rnf7 ring finger protein 7 JBrowse link 8 104,326,719 104,336,098 RGD:1624291
G Robo1 roundabout guidance receptor 1 JBrowse link 11 9,079,291 10,146,302 RGD:1600115
RGD:1624291
G Rps27l ribosomal protein S27-like JBrowse link 8 72,741,155 72,746,090 RGD:1624291
RGD:1600115
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:1624291
RGD:1600115
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:1600115
RGD:1624291
G Senp1 SUMO specific peptidase 1 JBrowse link 7 139,626,444 139,684,587 RGD:1624291
G Slc11a2 solute carrier family 11 member 2 JBrowse link 7 142,025,812 142,062,892 RGD:1624291
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1624291
RGD:1600115
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:1624291
RGD:1600115
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:1624291
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
G Tnfsf15 TNF superfamily member 15 JBrowse link 5 79,553,935 79,569,974 RGD:634236
RGD:13792537
RGD:1600115
RGD:1624291
G Vcp valosin-containing protein JBrowse link 5 58,426,548 58,445,953 RGD:1624291
RGD:1600115
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:1600115
RGD:1624291
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:1624291
RGD:13792537
G Bak1 BCL2-antagonist/killer 1 JBrowse link 20 5,609,620 5,618,899 RGD:1624291
RGD:1600115
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Bok BCL2 family apoptosis regulator BOK JBrowse link 9 100,829,593 100,840,498 RGD:1624291
RGD:1600115
G Cops5 COP9 signalosome subunit 5 JBrowse link 5 8,876,090 8,894,345 RGD:1624291
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:1624291
G Diablo diablo, IAP-binding mitochondrial protein JBrowse link 12 38,490,230 38,503,344 RGD:1624291
RGD:13792537
G LOC100360940 diablo-like JBrowse link 5 147,607,350 147,608,936 RGD:13792537
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:1624291
RGD:1600115
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1624291
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:2301029
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:1624291
G Gsn gelsolin JBrowse link 3 14,456,106 14,508,922 RGD:1624291
RGD:1600115
G Htra2 HtrA serine peptidase 2 JBrowse link 4 113,883,671 113,886,833 RGD:1624291
RGD:1600115
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G Prr7 proline rich 7 (synaptic) JBrowse link 17 9,693,274 9,702,795 RGD:1600115
RGD:1624291
G St18 ST18 C2H2C-type zinc finger transcription factor JBrowse link 5 12,437,617 12,787,223 RGD:1600115
RGD:1624291
G Tfap4 transcription factor AP-4 JBrowse link 10 11,204,616 11,222,975 RGD:1624291
RGD:1600115
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rps3 ribosomal protein S3 JBrowse link 1 164,435,868 164,441,167 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18179
    cellular process 16288
      positive regulation of cellular process 5538
        positive regulation of cell death 738
          positive regulation of programmed cell death 671
            positive regulation of apoptotic process 666
              positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 131
                activation of cysteine-type endopeptidase activity involved in apoptotic process + 81
                positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway + 10
                positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis + 1
Path 2
Term Annotations click to browse term
  biological_process 18179
    metabolic process 10866
      organic substance metabolic process 10300
        macromolecule metabolic process 8834
          protein metabolic process 5607
            cellular protein metabolic process 4948
              regulation of cellular protein metabolic process 2673
                positive regulation of cellular protein metabolic process 1624
                  positive regulation of proteolysis 358
                    positive regulation of peptidase activity 186
                      positive regulation of endopeptidase activity 169
                        positive regulation of cysteine-type endopeptidase activity 148
                          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 131
                            activation of cysteine-type endopeptidase activity involved in apoptotic process + 81
                            positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway + 10
                            positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.