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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
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Accession:GO:0043280 term browser browse the term
Definition:Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
Synonyms:exact_synonym: up regulation of caspase activity;   upregulation of caspase activity
 narrow_synonym: activation of caspase activity;   stimulation of caspase activity
 broad_synonym: positive regulation of caspase activity


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positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07071968.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:178,366,635...178,367,828 JBrowse link
G AC114204.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr15:27,407,962...27,408,258 JBrowse link
G AC128290.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr10:36,501,996...36,502,313 JBrowse link
G Acvr1c activin A receptor type 1C ISO
IEA
(PMID:15150278)
GO_REF:0000107
RGD
Ensembl
PMID:15150278 GO_REF:0000107 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15105833 RGD:2313858 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G App amyloid beta precursor protein ISO (PMID:21803450) RGD PMID:21803450 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 IEA
ISO
GO_REF:0000107
(PMID:18387645)
Ensembl
RGD
PMID:18387645 GO_REF:0000107 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arrb1 arrestin, beta 1 IMP RGD PMID:19171933 RGD:5510006 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Bad BCL2-associated agonist of cell death ISO
ISS
(PMID:18402937)
GO_REF:0000024
RGD
UniProt
PMID:18402937 GO_REF:0000024 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bbc3 Bcl-2 binding component 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcap31 B-cell receptor-associated protein 31 ISO (PMID:21183955) RGD PMID:21183955 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bcl10 BCL10, immune signaling adaptor ISO (MGI:MGI:1355482|PMID:10753917)
(PMID:22267217)
RGD PMID:10753917, PMID:22267217 MGI:MGI:1355482 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2l11 BCL2 like 11 ISO MGI:MGI:2156498 (MGI:MGI:3581932|PMID:15967824) RGD PMID:15967824 MGI:MGI:3581932 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Card9 caspase recruitment domain family, member 9 ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 3:3,798,346...3,806,841
Ensembl chr 3:3,798,347...3,806,713
JBrowse link
G Casp1 caspase 1 ISO (PMID:16920334) RGD PMID:16920334 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 IMP RGD PMID:17083921 RGD:2311464 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Ccn1 cellular communication network factor 1 ISO
IEA
UniProtKB:P48023 (MGI:MGI:3849354|PMID:19364818)
GO_REF:0000107
RGD
Ensembl
PMID:19364818 GO_REF:0000107, MGI:MGI:3849354 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 IMP caspase 3/7 RGD PMID:19625611 RGD:2314487 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Clec7a C-type lectin domain containing 7A ISO (PMID:22267217) RGD PMID:22267217 NCBI chr 4:163,216,152...163,227,367
Ensembl chr 4:163,216,163...163,227,334
JBrowse link
G Ctsd cathepsin D ISO (PMID:12107093) RGD PMID:12107093 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cycs cytochrome c, somatic IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyct cytochrome c, testis IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:63,204,779...63,211,847
Ensembl chr 3:62,818,502...63,211,845
JBrowse link
G Dapk1 death associated protein kinase 1 ISO (PMID:16132846) RGD PMID:16132846 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:16301996) RGD PMID:16301996 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO
ISS
(PMID:10692450)
GO_REF:0000024
RGD
UniProt
PMID:10692450 GO_REF:0000024 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fas Fas cell surface death receptor IMP RGD PMID:15519734 RGD:8662904 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fis1 fission, mitochondrial 1 ISO (PMID:21183955) RGD PMID:21183955 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Foxl2 forkhead box L2 ISO (PMID:16153597) RGD PMID:16153597 NCBI chr 8:107,194,492...107,197,644
Ensembl chr 8:107,194,551...107,195,675
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gramd4 GRAM domain containing 4 ISO
IBA
(PMID:15565177)
PMID:21873635
RGD PMID:15565177, PMID:21873635 RGD:13792537 NCBI chr 7:126,939,819...127,013,455
Ensembl chr 7:126,939,925...127,013,486
JBrowse link
G Hmgb1 high mobility group box 1 ISO (PMID:19800306) RGD PMID:19800306 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO (PMID:11583623), (PMID:11604410), (PMID:11967569), (PMID:17297443) RGD PMID:11583623, PMID:11604410, PMID:11967569, PMID:17297443 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Il24 interleukin 24 ISO (MGI:MGI:3821693|PMID:18708357) RGD PMID:18708357 MGI:MGI:3821693 NCBI chr13:47,618,451...47,623,849
Ensembl chr13:47,618,452...47,623,849
JBrowse link
G LOC100363502 cytochrome c, somatic-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:62,475,574...62,476,771
Ensembl chr18:62,476,383...62,476,700
Ensembl chr 4:62,476,383...62,476,700
JBrowse link
G LOC690675 similar to Cytochrome c, somatic IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:36,501,980...36,502,362 JBrowse link
G Malt1 MALT1 paracaspase ISO (PMID:22267217) RGD PMID:22267217 NCBI chr18:61,108,712...61,162,446
Ensembl chr18:61,109,069...61,162,445
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 ISO (PMID:20674765) RGD PMID:20674765 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:14522843 RGD:2304239 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Men1 menin 1 ISO (MGI:MGI:3037372|PMID:14688275) RGD PMID:14688275 MGI:MGI:3037372 NCBI chr 1:221,704,394...221,710,343
Ensembl chr 1:221,704,493...221,710,331
JBrowse link
G Mtch2 mitochondrial carrier 2 ISO MGI:MGI:2449949|MGI:MGI:5566664 (MGI:MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO
ISS
(PMID:19179467)
GO_REF:0000024
RGD
UniProt
PMID:19179467 GO_REF:0000024 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 ISO UniProtKB:O43464 (PMID:17297443) RGD PMID:17297443 NCBI chr16:21,275,311...21,282,246
Ensembl chr16:21,275,311...21,282,246
JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO
ISS
(PMID:20599703)
GO_REF:0000024
RGD
UniProt
PMID:20599703 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B ISO (PMID:11821383), (PMID:15030775) RGD PMID:11821383, PMID:15030775 NCBI chr10:57,755,957...57,847,867 JBrowse link
G Nlrp2 NLR family pyrin domain containing 2 ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 1:73,082,648...73,121,118
Ensembl chr 1:73,082,977...73,121,085
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO
IBA
(PMID:15030775)
PMID:21873635
RGD PMID:15030775, PMID:21873635 RGD:13792537 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO (PMID:10329646) RGD PMID:10329646 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951
JBrowse link
G Nodal nodal growth differentiation factor ISO (PMID:15150278) RGD PMID:15150278 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Pdcd5 programmed cell death 5 ISO (PMID:16374546) RGD PMID:16374546 NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
JBrowse link
G Pdcd6 programmed cell death 6 ISO (PMID:16132846) RGD PMID:16132846 NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 ISO (PMID:14699081) RGD PMID:14699081 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F IDA
IBA
ISO
PMID:11559703
PMID:21873635
(PMID:11559703)
RGD PMID:11559703, PMID:11559703, PMID:21873635 RGD:8553939, RGD:13792537 NCBI chr11:88,313,709...88,343,726
Ensembl chr11:88,313,709...88,343,627
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:18322138 RGD:8693423 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Pycard PYD and CARD domain containing IMP
ISO
(PMID:15030775), (PMID:22267217) RGD PMID:15030775, PMID:22267217, PMID:19401709 RGD:5491174 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rest RE1-silencing transcription factor ISO
ISS
(PMID:20564196)
GO_REF:0000024
RGD
UniProt
PMID:20564196 GO_REF:0000024 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17425560 RGD:1642961 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Sirt1 sirtuin 1 ISO
IEA
(PMID:19047049)
GO_REF:0000107
RGD
Ensembl
PMID:19047049 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sox7 SRY-box transcription factor 7 ISO (PMID:19108950) RGD PMID:19108950 NCBI chr15:47,293,699...47,300,460
Ensembl chr15:47,293,699...47,300,460
JBrowse link
G Syk spleen associated tyrosine kinase ISO
IEA
(PMID:22267217)
GO_REF:0000107
RGD
Ensembl
PMID:22267217 GO_REF:0000107 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:11577081) RGD PMID:11577081 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 ISO (PMID:21459798), (PMID:21525171), (PMID:22266862) RGD PMID:21459798, PMID:21525171, PMID:22266862 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats ISO
IBA
MGI:MGI:3043446 (MGI:MGI:3056865|PMID:15271982)
PMID:21873635
RGD PMID:15271982, PMID:21873635 MGI:MGI:3056865, RGD:13792537 NCBI chr 8:65,686,586...65,774,940
Ensembl chr 8:65,686,648...65,774,989
JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:20193664 RGD:11553917 NCBI chr 6:34,094,291...34,152,048
Ensembl chr 6:34,094,306...34,151,622
JBrowse link
G Wnt3a Wnt family member 3A ISO (MGI:MGI:3702339|PMID:17251350) RGD PMID:17251350 MGI:MGI:3702339 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07067042.3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 9:27,554,751...27,556,861 JBrowse link
G Acer2 alkaline ceramidase 2 ISO (PMID:20628055) RGD PMID:20628055 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 ISO
ISS
(PMID:17094969)
GO_REF:0000024
RGD
UniProt
PMID:17094969 GO_REF:0000024 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Anp32b acidic nuclear phosphoprotein 32 family member B IEA
ISO
GO_REF:0000107
(PMID:20015864)
Ensembl
RGD
PMID:20015864 GO_REF:0000107 NCBI chr 5:62,070,709...62,094,633
Ensembl chr 5:62,071,346...62,094,633
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 ISO (PMID:21827945)
MGI:MGI:1349414|MGI:MGI:1857868|MGI:MGI:1928692 (MGI:MGI:3575207|PMID:15776018), (MGI:MGI:3577148|PMID:15703386)
RGD PMID:15703386, PMID:15776018, PMID:21827945 MGI:MGI:3575207, MGI:MGI:3577148 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO
IEA
(PMID:16725111)
GO_REF:0000107
RGD
Ensembl
PMID:16725111 GO_REF:0000107 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Bad BCL2-associated agonist of cell death ISO
ISS
(MGI:MGI:4453294|PMID:19915011)
GO_REF:0000024
RGD
UniProt
PMID:19915011 GO_REF:0000024, MGI:MGI:4453294 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO MGI:MGI:2159364|MGI:MGI:99702 (MGI:MGI:2667259|PMID:12847083), (MGI:MGI:3575207|PMID:15776018), (MGI:MGI:3662939|PMID:16893972) RGD PMID:12847083, PMID:15776018, PMID:16893972 MGI:MGI:2667259, MGI:MGI:3575207, MGI:MGI:3662939 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISS
ISO
GO_REF:0000024
MGI:MGI:1097161|MGI:MGI:1857429|MGI:MGI:2158306 (MGI:MGI:2667259|PMID:12847083), (MGI:MGI:3041326|PMID:14561915), (MGI:MGI:3575207|PMID:15776018), (MGI:MGI:3692043|PMID:14502238), (MGI:MGI:5009404|PMID:16735463)
(PMID:11350920), (PMID:11912183)
UniProt
RGD
PMID:11350920, PMID:11912183, PMID:12847083, PMID:14502238, PMID:14561915, PMID:15776018, PMID:16735463 GO_REF:0000024, MGI:MGI:2667259, MGI:MGI:3041326, MGI:MGI:3575207, MGI:MGI:3692043, MGI:MGI:5009404 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 ISO
IBA
(PMID:11463392), (PMID:17024184)
PMID:21873635
RGD PMID:11463392, PMID:17024184, PMID:21873635 RGD:13792537 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2l11 BCL2 like 11 ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bid BH3 interacting domain death agonist ISO
IBA
MGI:MGI:2158671 (MGI:MGI:2183141|PMID:12011074)
PMID:21873635
RGD PMID:12011074, PMID:21873635 MGI:MGI:2183141, RGD:13792537 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bok BCL2 family apoptosis regulator BOK ISO
ISS
(PMID:20673843)
GO_REF:0000024
RGD
UniProt
PMID:20673843 GO_REF:0000024 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Casp1 caspase 1 NOT IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 NOT IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp2 caspase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp4 caspase 4 NOT TAS
IBA
PMID:21873635 RGD
GO_Central
PMID:11684090, PMID:21873635 RGD:632459, RGD:13792537 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp8 caspase 8 ISO
IBA
(MGI:MGI:2183141|PMID:12011074)
PMID:21873635
RGD PMID:12011074, PMID:21873635 MGI:MGI:2183141, RGD:13792537 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 ISO
IBA
(MGI:MGI:1347587|PMID:10235259)
PMID:21873635
(PMID:17245429)
RGD PMID:10235259, PMID:17245429, PMID:21873635 MGI:MGI:1347587, RGD:13792537 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668
JBrowse link
G Casp9 caspase 9 ISO
IBA
MGI:MGI:2158755 (MGI:MGI:3575207|PMID:15776018)
PMID:21873635
RGD PMID:15776018, PMID:21873635 MGI:MGI:3575207, RGD:13792537 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Col4a3 collagen type IV alpha 3 chain ISO (PMID:10766752) RGD PMID:10766752 NCBI chr 9:88,357,528...88,484,735
Ensembl chr 9:88,357,556...88,485,830
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain ISO
IBA
MGI:MGI:1889507 (MGI:MGI:3603971|PMID:16183742)
PMID:21873635
RGD PMID:16183742, PMID:21873635 MGI:MGI:3603971, RGD:13792537 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588
JBrowse link
G Ctsh cathepsin H IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Dap death-associated protein ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO (MGI:MGI:2183141|PMID:12011074), (MGI:MGI:3587135|PMID:16085184) RGD PMID:12011074, PMID:16085184 MGI:MGI:2183141, MGI:MGI:3587135 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein IEA
ISO
GO_REF:0000107
(PMID:17888903)
Ensembl
RGD
PMID:17888903 GO_REF:0000107 NCBI chr16:58,776,489...59,247,752
Ensembl chr16:59,077,574...59,247,754
JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 ISO (PMID:10411904) RGD PMID:10411904 NCBI chr10:11,059,701...11,085,186
Ensembl chr10:11,060,313...11,085,210
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20978507)
Ensembl
UniProt
RGD
PMID:20978507 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO MGI:MGI:2177666 (MGI:MGI:1858648|PMID:10882126) RGD PMID:10882126 MGI:MGI:1858648 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G F2r coagulation factor II (thrombin) receptor ISO
IEA
ISS
(PMID:10692450)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:10692450 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F3 coagulation factor III, tissue factor ISO
IEA
(PMID:17898544)
GO_REF:0000107
RGD
Ensembl
PMID:17898544 GO_REF:0000107 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fam162a family with sequence similarity 162, member A ISO
ISS
(PMID:15082785)
GO_REF:0000024
RGD
UniProt
PMID:15082785 GO_REF:0000024 NCBI chr11:67,618,683...67,646,253
Ensembl chr11:67,618,625...67,646,253
JBrowse link
G Faslg Fas ligand ISO UniProtKB:P18406 (PMID:18293083), (PMID:19364818) RGD PMID:18293083, PMID:19364818 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Hip1 huntingtin interacting protein 1 ISO
IBA
(PMID:11788820)
PMID:21873635
RGD PMID:11788820, PMID:21873635 RGD:13792537 NCBI chr12:24,180,795...24,315,373
Ensembl chr12:24,180,937...24,315,373
JBrowse link
G Hip1r huntingtin interacting protein 1 related ISO
IBA
(PMID:19255499)
PMID:21873635
RGD PMID:19255499, PMID:21873635 RGD:13792537 NCBI chr12:38,024,517...38,053,184
Ensembl chr12:38,024,519...38,053,085
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 ISO (PMID:17823127) RGD PMID:17823127 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Ift57 intraflagellar transport 57 ISO (PMID:11788820) RGD PMID:11788820 NCBI chr11:53,664,638...53,731,779
Ensembl chr11:53,664,638...53,731,779
JBrowse link
G Jak2 Janus kinase 2 ISO (MGI:MGI:5009182|PMID:12426001) RGD PMID:12426001 MGI:MGI:5009182 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Khdc1 KH domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:27,546,069...27,547,769
Ensembl chr 9:27,546,528...27,547,473
JBrowse link
G Khdc1b KH domain containing 1B ISO (MGI:MGI:2683352|PMID:14657025) RGD PMID:14657025 MGI:MGI:2683352 NCBI chr 9:27,554,436...27,556,770 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase ISO
IEA
(PMID:16116473)
GO_REF:0000107
RGD
Ensembl
PMID:16116473 GO_REF:0000107 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G LOC100911519 p53-induced protein with a death domain-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,976,399...213,988,807
Ensembl chr 1:214,419,240...214,423,881
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mtch1 mitochondrial carrier 1 ISO (PMID:12377771) RGD PMID:12377771 NCBI chr20:6,937,341...6,961,165
Ensembl chr20:6,937,347...6,961,162
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 ISO (PMID:18591963) RGD PMID:18591963 NCBI chr 5:156,855,105...156,864,517
Ensembl chr 5:156,850,206...156,864,517
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor ISO (MGI:MGI:2677658|PMID:14517295) RGD PMID:14517295 MGI:MGI:2677658 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ngf nerve growth factor ISO UniProtKB:P08138 (PMID:11927634) RGD PMID:11927634 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Ngfr nerve growth factor receptor IEA
ISO
GO_REF:0000107
(PMID:26268439)
Ensembl
RGD
PMID:26268439 GO_REF:0000107 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Nkx3-1 NK3 homeobox 1 ISS
ISO
GO_REF:0000024
(PMID:17486276), (PMID:19266349)
UniProt
RGD
PMID:17486276, PMID:19266349 GO_REF:0000024 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 ISO (PMID:15030775) RGD PMID:15030775 NCBI chr 6:22,167,874...22,194,755
Ensembl chr 6:22,167,919...22,194,250
JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A ISO
IBA
(PMID:15212762)
PMID:21873635
RGD PMID:15212762, PMID:21873635 RGD:13792537 NCBI chr10:57,692,474...57,747,608
Ensembl chr10:57,692,474...57,822,498
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO MGI:MGI:3686871 (MGI:MGI:3697006|PMID:17008311) RGD PMID:17008311 MGI:MGI:3697006 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 ISO (PMID:10329646) RGD PMID:10329646 NCBI chr 4:85,123,965...85,175,206
Ensembl chr 4:85,123,960...85,174,951
JBrowse link
G P2rx1 purinergic receptor P2X 1 ISO (MGI:MGI:3640029|PMID:16325464) RGD PMID:16325464 MGI:MGI:3640029 NCBI chr10:59,566,268...59,581,328
Ensembl chr10:59,566,223...59,581,325
JBrowse link
G Pdcd2 programmed cell death 2 ISO (PMID:20605493) RGD PMID:20605493 NCBI chr 1:57,512,968...57,518,458
Ensembl chr 1:57,512,968...57,518,458
JBrowse link
G Pdcd6 programmed cell death 6 ISO (MGI:MGI:2684521|PMID:14561754) RGD PMID:14561754 MGI:MGI:2684521 NCBI chr 1:31,576,183...31,591,852
Ensembl chr 1:31,576,183...31,591,849
JBrowse link
G Pidd1 p53-induced death domain protein 1 ISO
IBA
MGI:MGI:1336168 (MGI:MGI:3603971|PMID:16183742)
PMID:21873635
(PMID:17159900)
RGD PMID:16183742, PMID:17159900, PMID:21873635 MGI:MGI:3603971, RGD:13792537 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 ISO (MGI:MGI:5009174|PMID:14699081) RGD PMID:14699081 MGI:MGI:5009174 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pml PML nuclear body scaffold ISO MGI:MGI:2429949 (MGI:MGI:1306978|PMID:9806545) RGD PMID:9806545 MGI:MGI:1306978 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO (PMID:18293083) RGD PMID:18293083 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Pycard PYD and CARD domain containing ISO MGI:MGI:3686870 (MGI:MGI:3697006|PMID:17008311) RGD PMID:17008311 MGI:MGI:3697006 NCBI chr 1:199,438,029...199,439,062
Ensembl chr 1:199,437,832...199,439,210
JBrowse link
G Rack1 receptor for activated C kinase 1 ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:34,149,717...34,155,198
Ensembl chr10:34,149,717...34,155,198
Ensembl chr12:34,149,717...34,155,198
JBrowse link
G Ret ret proto-oncogene ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:150,202,170...150,249,196
Ensembl chr 4:150,202,058...150,244,372
JBrowse link
G Rnf7 ring finger protein 7 ISO (MGI:MGI:1333612|PMID:10082581) RGD PMID:10082581 MGI:MGI:1333612 NCBI chr 8:104,326,719...104,336,098
Ensembl chr 8:104,326,719...104,335,729
JBrowse link
G Robo1 roundabout guidance receptor 1 IEA
ISO
GO_REF:0000107
(PMID:18566128)
Ensembl
RGD
PMID:18566128 GO_REF:0000107 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Rps27l ribosomal protein S27-like ISO (PMID:17057733) RGD PMID:17057733 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G S100a8 S100 calcium binding protein A8 ISO
ISS
(PMID:19935772)
GO_REF:0000024
RGD
UniProt
PMID:19935772 GO_REF:0000024 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19935772)
Ensembl
UniProt
RGD
PMID:19935772 GO_REF:0000024, GO_REF:0000107 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Senp1 SUMO specific peptidase 1 ISO (PMID:1087798) RGD PMID:1087798 NCBI chr 7:139,626,444...139,684,587
Ensembl chr 7:139,630,515...139,675,245
JBrowse link
G Slc11a2 solute carrier family 11 member 2 ISO (PMID:18082289) RGD PMID:18082289 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc1a1 solute carrier family 1 member 1 ISO (MGI:MGI:5508628|PMID:16858406) RGD PMID:16858406 MGI:MGI:5508628 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Slc22a2 solute carrier family 22 member 2 IMP PMID:30120945 ARUK-UCL PMID:30120945 RGD:30309911 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Smad3 SMAD family member 3 ISO (PMID:15107418) RGD PMID:15107418 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Snca synuclein alpha ISO (PMID:21050448) RGD PMID:21050448 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO (MGI:MGI:5447631|PMID:10692450) RGD PMID:10692450 MGI:MGI:5447631 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tnf tumor necrosis factor ISO (MGI:MGI:3603971|PMID:16183742)
(PMID:16723520)
RGD PMID:16183742, PMID:16723520 MGI:MGI:3603971 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfsf15 TNF superfamily member 15 IDA
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
(PMID:11911831)
Ensembl
RGD
PMID:11911831, PMID:11911831, PMID:21873635 GO_REF:0000107, RGD:634236, RGD:13792537 NCBI chr 5:79,553,935...79,569,974
Ensembl chr 5:79,553,742...79,570,073
JBrowse link
G Vcp valosin-containing protein ISO (MGI:MGI:2684521|PMID:14561754) RGD PMID:14561754 MGI:MGI:2684521 NCBI chr 5:58,426,548...58,445,953
Ensembl chr 5:58,426,549...58,445,953
JBrowse link
G Xdh xanthine dehydrogenase IEA
ISO
GO_REF:0000107
(PMID:18386220)
Ensembl
RGD
PMID:18386220 GO_REF:0000107 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 ISO (PMID:9267021) RGD PMID:9267021 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Bak1 BCL2-antagonist/killer 1 ISO MGI:MGI:2159364 (MGI:MGI:2178486|PMID:11836241) RGD PMID:11836241 MGI:MGI:2178486 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO
ISS
IEA
(PMID:15214043)
MGI:MGI:1857429 (MGI:MGI:1203837|PMID:9560217), (MGI:MGI:2178486|PMID:11836241)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:9560217, PMID:11836241, PMID:15214043 GO_REF:0000024, GO_REF:0000107, MGI:MGI:1203837, MGI:MGI:2178486 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bok BCL2 family apoptosis regulator BOK ISO
ISS
(MGI:MGI:5648772|PMID:26015568)
GO_REF:0000024
RGD
UniProt
PMID:26015568 GO_REF:0000024, MGI:MGI:5648772 NCBI chr 9:100,829,593...100,840,498
Ensembl chr 9:100,829,552...100,840,504
JBrowse link
G Cops5 COP9 signalosome subunit 5 ISO (PMID:24091666) RGD PMID:24091666 NCBI chr 5:8,876,090...8,894,345
Ensembl chr 5:8,876,044...8,894,339
JBrowse link
G Cycs cytochrome c, somatic ISO MGI:MGI:2154447|MGI:MGI:3581449 (MGI:MGI:1858667|PMID:10830166), (MGI:MGI:2681362|PMID:14623868), (MGI:MGI:3580764|PMID:15907471) RGD PMID:10830166, PMID:14623868, PMID:15907471 MGI:MGI:1858667, MGI:MGI:2681362, MGI:MGI:3580764 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO
IBA
(MGI:MGI:2681362|PMID:14623868)
PMID:21873635
RGD PMID:14623868, PMID:21873635 MGI:MGI:2681362, RGD:13792537 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G LOC100360940 diablo-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:147,607,350...147,608,936
Ensembl chr 5:147,607,552...147,609,050
JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator ISO
IEA
(MGI:MGI:1344924|PMID:10479688)
GO_REF:0000107
RGD
Ensembl
PMID:10479688 GO_REF:0000107, MGI:MGI:1344924 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Jak2 Janus kinase 2 ISO (MGI:MGI:5009182|PMID:12426001) RGD PMID:12426001 MGI:MGI:5009182 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Smad3 SMAD family member 3 IMP TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fas Fas cell surface death receptor ISO
IBA
(PMID:11096076)
PMID:21873635
RGD PMID:11096076, PMID:21873635 RGD:13792537 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Gsn gelsolin ISO (PMID:22952982) RGD PMID:22952982 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO (PMID:11602612) RGD PMID:11602612 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Lgals9 galectin 9 ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Prr7 proline rich 7 (synaptic) ISS
ISO
GO_REF:0000024
(PMID:21460222)
UniProt
RGD
PMID:21460222 GO_REF:0000024 NCBI chr17:9,693,274...9,702,795
Ensembl chr17:9,694,168...9,695,292
JBrowse link
G St18 ST18 C2H2C-type zinc finger transcription factor IEA
ISO
GO_REF:0000107
(PMID:18676404)
Ensembl
RGD
PMID:18676404 GO_REF:0000107 NCBI chr 5:12,437,617...12,787,223
Ensembl chr 5:12,437,525...12,563,429
JBrowse link
G Tfap4 transcription factor AP-4 ISO (MGI:MGI:4456943|PMID:15944155) RGD PMID:15944155 MGI:MGI:4456943 NCBI chr10:11,204,616...11,222,975
Ensembl chr10:11,206,226...11,223,370
JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rps3 ribosomal protein S3 ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:164,435,868...164,441,167
Ensembl chr 1:164,435,878...164,441,167
JBrowse link
G Tnf tumor necrosis factor IMP RGD PMID:12131680 RGD:14995454 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    biological regulation 13773
      regulation of molecular function 3077
        regulation of catalytic activity 2353
          regulation of hydrolase activity 1309
            regulation of peptidase activity 506
              regulation of endopeptidase activity 481
                regulation of cysteine-type endopeptidase activity 256
                  regulation of cysteine-type endopeptidase activity involved in apoptotic process 232
                    positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 140
                      activation of cysteine-type endopeptidase activity involved in apoptotic process + 85
                      positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway + 10
                      positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis + 2
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        macromolecule metabolic process 10086
          protein metabolic process 6228
            cellular protein metabolic process 5570
              regulation of cellular protein metabolic process 2805
                positive regulation of cellular protein metabolic process 1707
                  positive regulation of proteolysis 376
                    positive regulation of peptidase activity 198
                      positive regulation of endopeptidase activity 180
                        positive regulation of cysteine-type endopeptidase activity 157
                          positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 140
                            activation of cysteine-type endopeptidase activity involved in apoptotic process + 85
                            positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway + 10
                            positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.