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ONTOLOGY REPORT - ANNOTATIONS


Term:leukocyte degranulation
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Accession:GO:0043299 term browser browse the term
Definition:The regulated exocytosis of secretory granules by a leukocyte.
Synonyms:exact_synonym: immune cell degranulation;   immune cell granule exocytosis;   leucocyte degranulation;   leukocyte granule exocytosis


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basophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pi4k2a phosphatidylinositol 4-kinase type 2 alpha IMP RGD PMID:17122963 RGD:2306407 NCBI chr 1:261,337,594...261,362,509
Ensembl chr 1:261,337,594...261,362,509
JBrowse link
cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rab27a RAB27A, member RAS oncogene family ISO MGI:MGI:1856656 (MGI:MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:MGI:3653524 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221
JBrowse link
G Stx11 syntaxin 11 ISO MGI:MGI:5461477 (MGI:MGI:5460953|PMID:23042080), (MGI:MGI:5471188|PMID:23190531) RGD PMID:23042080, PMID:23190531 MGI:MGI:5460953, MGI:MGI:5471188 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 ISO
ISS
(PMID:10706735)
GO_REF:0000024
RGD
UniProt
PMID:10706735 GO_REF:0000024 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO (PMID:16677249) RGD PMID:16677249 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 IDA
ISO
PMID:14993220
(PMID:16677249)
RGD PMID:16677249, PMID:14993220 RGD:8553828 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 NOT ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link
histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07053516.1 IEA GO_REF:0000107 Ensembl GO_REF:0000107 Ensembl chr 3:112,346,627...112,361,216 JBrowse link
G Adora3 adenosine A3 receptor ISO MGI:MGI:2155986 (MGI:MGI:2664591|PMID:12817016) RGD PMID:12817016 MGI:MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:12220673 RGD:1600535 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Snap23 synaptosome associated protein 23 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta IMP RGD PMID:12499633 RGD:1625716 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link
mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbl Cbl proto-oncogene IEP RGD PMID:18243321 RGD:11576314 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Chga chromogranin A IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:21214543)
Ensembl
UniProt
RGD
PMID:21214543 GO_REF:0000024, GO_REF:0000107 NCBI chr 6:126,434,226...126,445,569
Ensembl chr 6:126,434,226...126,445,568
JBrowse link
G Clnk cytokine-dependent hematopoietic cell linker ISO
IEA
(MGI:MGI:2179131|PMID:10744659)
GO_REF:0000107
RGD
Ensembl
PMID:10744659 GO_REF:0000107, MGI:MGI:2179131 NCBI chr14:76,657,165...76,834,050
Ensembl chr14:76,657,311...76,833,161
JBrowse link
G Cplx2 complexin 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:10,756,871...10,828,811
Ensembl chr17:10,756,285...10,818,835
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO (PMID:20100931) RGD PMID:20100931 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Lat linker for activation of T cells IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:197,765,644...197,770,669
Ensembl chr 1:197,765,644...197,770,669
JBrowse link
G Lat2 linker for activation of T cells family, member 2 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr12:25,114,099...25,128,381
Ensembl chr12:25,119,355...25,125,749
JBrowse link
G Milr1 mast cell immunoglobulin-like receptor 1 ISO
IEA
ISS
(MGI:MGI:4461821|PMID:20526344)
GO_REF:0000002
GO_REF:0000024
RGD
InterPro
UniProt
PMID:20526344 GO_REF:0000002, GO_REF:0000024, MGI:MGI:4461821 NCBI chr10:94,944,243...94,961,795
Ensembl chr10:94,944,436...94,961,791
JBrowse link
G Mrgprx2 MAS related GPR family member X2 ISO (PMID:22069323) RGD PMID:22069323 NCBI chr 1:103,743,746...103,760,945
Ensembl chr 1:103,741,503...103,760,913
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 ISO
ISS
(MGI:MGI:5586645|PMID:24586680)
GO_REF:0000024
RGD
UniProt
PMID:24586680 GO_REF:0000024, MGI:MGI:5586645 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Pla2g3 phospholipase A2, group III ISO MGI:MGI:4461174 (MGI:MGI:5492190|PMID:23624557) RGD PMID:23624557 MGI:MGI:5492190 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Ptgdrl prostaglandin D2 receptor-like IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr15:18,089,077...18,095,979
Ensembl chr15:18,088,897...18,096,039
JBrowse link
G Ptgds prostaglandin D2 synthase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 ISO MGI:MGI:2386261 (MGI:MGI:3758152|PMID:17190838) RGD PMID:17190838 MGI:MGI:3758152 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Tac4 tachykinin precursor 4 IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:83,081,168...83,089,487
Ensembl chr10:83,081,168...83,089,481
JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A ISO (PMID:24760828) RGD PMID:24760828 NCBI chr 1:198,123,883...198,128,890
Ensembl chr 1:198,123,884...198,128,857
JBrowse link
G Rab27a RAB27A, member RAS oncogene family ISO MGI:MGI:1856656 (MGI:MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:MGI:3653524 NCBI chr 8:79,722,334...79,776,228
Ensembl chr 8:79,722,334...79,776,221
JBrowse link
G Stx11 syntaxin 11 ISO MGI:MGI:5461477 (MGI:MGI:5460953|PMID:23042080), (MGI:MGI:5471188|PMID:23190531) RGD PMID:23042080, PMID:23190531 MGI:MGI:5460953, MGI:MGI:5471188 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Unc13d unc-13 homolog D ISO
IEA
MGI:MGI:3628822 (MGI:MGI:3703574|PMID:17420270)
GO_REF:0000107
RGD
Ensembl
PMID:17420270 GO_REF:0000107, MGI:MGI:3703574 NCBI chr10:104,613,907...104,628,664
Ensembl chr10:104,613,928...104,628,676
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 ISO
ISS
(MGI:MGI:3699670|PMID:14662900)
GO_REF:0000024
RGD
BHF-UCL
PMID:14662900 GO_REF:0000024, MGI:MGI:3699670
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (MGI:MGI:3721168|PMID:12874256)
(PMID:16339535)
RGD PMID:12874256, PMID:16339535 MGI:MGI:3721168 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Cd84 CD84 molecule ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865
JBrowse link
G Foxf1 forkhead box F1 ISO MGI:MGI:2179135 (MGI:MGI:4367570|PMID:18421012) RGD PMID:18421012 MGI:MGI:4367570 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO
IEA
MGI:MGI:2653910 (MGI:MGI:3589858|PMID:15944273)
GO_REF:0000107
RGD
Ensembl
PMID:15944273 GO_REF:0000107, MGI:MGI:3589858 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Lgals9 galectin 9 ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO MGI:MGI:3051384 (MGI:MGI:3050742|PMID:15235600) RGD PMID:15235600 MGI:MGI:3050742 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 ISO (MGI:MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:MGI:5491117 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase ISO
IEA
MGI:MGI:88141 (MGI:MGI:4366690|PMID:19703997)
GO_REF:0000107
RGD
Ensembl
PMID:19703997 GO_REF:0000107, MGI:MGI:4366690 NCBI chr10:64,565,121...64,657,079
Ensembl chr10:64,567,268...64,657,089
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase ISO MGI:MGI:107771 (MGI:MGI:4366690|PMID:19703997) RGD PMID:19703997 MGI:MGI:4366690 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
JBrowse link
neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa3 annexin A3 ISO (PMID:9550422) RGD PMID:9550422 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Myo1f myosin IF ISO MGI:MGI:3664779 (MGI:MGI:3664353|PMID:17023661) RGD PMID:17023661 MGI:MGI:3664353 NCBI chr 7:18,440,742...18,491,448
Ensembl chr 7:18,440,742...18,491,448
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing NOT ISO (MGI:MGI:6103777|PMID:28779020) RGD PMID:28779020 MGI:MGI:6103777 NCBI chr 9:71,911,744...72,005,816
Ensembl chr 9:71,915,421...72,005,838
JBrowse link
G Stx11 syntaxin 11 ISO MGI:MGI:5461477 (MGI:MGI:5460953|PMID:23042080) RGD PMID:23042080 MGI:MGI:5460953 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Stxbp2 syntaxin binding protein 2 IEA
ISO
GO_REF:0000107
(PMID:18588921)
Ensembl
RGD
PMID:18588921 GO_REF:0000107 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
G Stxbp3 syntaxin binding protein 3 ISO (PMID:18588921) RGD PMID:18588921 NCBI chr 2:211,595,763...211,638,756
Ensembl chr 2:211,595,659...211,638,788
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT ISO (PMID:16677249) RGD PMID:16677249 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 IDA
ISO
PMID:14993220
(PMID:16677249)
RGD PMID:16677249, PMID:14993220 RGD:8553828 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 NOT ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link
positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 ISO (PMID:11714832) RGD PMID:11714832 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Stx4 syntaxin 4 IEA
ISO
GO_REF:0000107
(PMID:16677249)
Ensembl
RGD
PMID:16677249 GO_REF:0000107 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Pla2g3 phospholipase A2, group III ISO
IEA
(PMID:23624557)
GO_REF:0000107
(MGI:MGI:5492190|PMID:23624557)
RGD
Ensembl
PMID:23624557 GO_REF:0000107, MGI:MGI:5492190 NCBI chr14:83,724,828...83,730,614
Ensembl chr14:83,724,933...83,730,614
JBrowse link
G Snx4 sorting nexin 4 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr11:70,693,381...70,753,620
Ensembl chr11:70,693,366...70,753,632
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO (PMID:18253931) RGD PMID:18253931 NCBI chr12:18,996,566...19,033,714
Ensembl chr12:18,996,591...19,030,381
JBrowse link
G Vamp8 vesicle-associated membrane protein 8 IEA
ISO
GO_REF:0000107
(PMID:18253931)
Ensembl
RGD
PMID:18253931 GO_REF:0000107 NCBI chr 4:100,250,301...100,252,756
Ensembl chr 4:100,250,301...100,252,755
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2B receptor ISO
IEA
(MGI:MGI:3776334|PMID:11454903)
GO_REF:0000107
RGD
Ensembl
PMID:11454903 GO_REF:0000107, MGI:MGI:3776334 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adora3 adenosine A3 receptor ISO MGI:MGI:2155986 (MGI:MGI:2664591|PMID:12817016) RGD PMID:12817016 MGI:MGI:2664591 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IMP RGD PMID:18209484 RGD:5130941 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:MGI:85068|PMID:9000133) RGD PMID:9000133 MGI:MGI:85068 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO MGI:MGI:2384004 (MGI:MGI:3029067|PMID:14764707) RGD PMID:14764707 MGI:MGI:3029067 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO
ISS
(MGI:MGI:5294498|PMID:21746961)
GO_REF:0000024
RGD
UniProt
PMID:21746961 GO_REF:0000024, MGI:MGI:5294498 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Gab2 GRB2-associated binding protein 2 ISO
ISS
(MGI:MGI:2137187|PMID:11449275)
GO_REF:0000024
RGD
UniProt
PMID:11449275 GO_REF:0000024, MGI:MGI:2137187 NCBI chr 1:162,082,876...162,283,379
Ensembl chr 1:162,083,030...162,279,727
JBrowse link
G Gata1 GATA binding protein 1 IMP RGD PMID:22390417 RGD:9587812 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata2 GATA binding protein 2 IMP RGD PMID:22390417 RGD:9587812 NCBI chr 4:120,129,028...120,142,490
Ensembl chr 4:120,133,713...120,142,488
JBrowse link
G Il13 interleukin 13 ISO MGI:MGI:1931804|MGI:MGI:96556 (MGI:MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:MGI:3589858 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il4 interleukin 4 ISO
IBA
MGI:MGI:1857195|MGI:MGI:96541 (MGI:MGI:3589858|PMID:15944273)
PMID:21873635
RGD PMID:15944273, PMID:21873635 MGI:MGI:3589858, RGD:13792537 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4r interleukin 4 receptor ISO MGI:MGI:1861951 (MGI:MGI:3589858|PMID:15944273) RGD PMID:15944273 MGI:MGI:3589858 NCBI chr 1:196,942,343...196,967,221
Ensembl chr 1:196,942,364...196,967,220
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 IMP RGD PMID:16177098 RGD:1578516 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386
JBrowse link
G Nppc natriuretic peptide C IDA PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Pld2 phospholipase D2 IMP RGD PMID:16861349 RGD:2299903 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Sphk2 sphingosine kinase 2 ISO (MGI:MGI:3703830|PMID:17346996) RGD PMID:17346996 MGI:MGI:3703830 NCBI chr 1:101,692,972...101,700,604
Ensembl chr 1:101,692,973...101,697,277
JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:23487749 RGD:12904029 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:23487749 RGD:12904029 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
G Syk spleen associated tyrosine kinase IMP
IBA
IEA
ISO
PMID:21873635
GO_REF:0000107
MGI:MGI:2384078 (MGI:MGI:85068|PMID:9000133)
Ensembl
RGD
PMID:9000133, PMID:16861349, PMID:21873635 GO_REF:0000107, MGI:MGI:85068, RGD:2299903, RGD:13792537 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:41,805,252...41,860,076 JBrowse link
G Cd160 CD160 molecule ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:198,933,681...198,965,380
Ensembl chr 2:198,935,133...198,942,732
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 ISO (PMID:23632890) RGD PMID:23632890 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
positive regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd177 CD177 molecule ISO
IBA
UniProtKB:P05107|UniProtKB:P11215 (PMID:21193407)
PMID:21873635
RGD PMID:21193407, PMID:21873635 RGD:13792537 NCBI chr 1:82,964,683...82,987,306
Ensembl chr 1:82,964,683...82,987,253
JBrowse link
G Itgam integrin subunit alpha M ISO UniProtKB:P05107|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgb2 integrin subunit beta 2 ISO UniProtKB:P11215|UniProtKB:Q8N6Q3 (PMID:21193407) RGD PMID:21193407 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G LOC100909620 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,555,412...81,560,629
Ensembl chr 1:81,555,412...81,559,685
JBrowse link
G LOC100909700 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,609,177...81,627,763
Ensembl chr 1:81,609,433...81,627,710
JBrowse link
G LOC100910565 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,548,679...81,551,288
Ensembl chr 1:81,548,892...81,550,598
JBrowse link
G LOC102553892 CD177 antigen-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,947,303...82,952,884
Ensembl chr 1:82,948,488...82,952,936
JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:2829894 RGD:10041060 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G RGD1564380 similar to BC049730 protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,830,153...82,902,864
Ensembl chr 1:82,831,952...82,918,444
JBrowse link
G RGD1565655 similar to BC049730 protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:81,592,004...81,597,637
Ensembl chr 1:81,593,800...81,596,819
JBrowse link
regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx6 sorting nexin 6 NOT ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 6:75,626,927...75,670,172
Ensembl chr 6:75,626,927...75,670,135
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT ISO (PMID:18253931) RGD PMID:18253931 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
G Vamp3 vesicle-associated membrane protein 3 NOT ISO (PMID:18253931) RGD PMID:18253931 NCBI chr 5:168,126,157...168,136,628
Ensembl chr 5:168,126,157...168,136,666
JBrowse link
regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:46,555,552...46,593,778
Ensembl chr15:46,555,188...46,593,653
JBrowse link
G Fer FER tyrosine kinase IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:111,557,804...111,868,583
Ensembl chr 9:111,597,037...111,862,670
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase ISO
IBA
(PMID:19001085)
PMID:21873635
RGD PMID:19001085, PMID:21873635 RGD:13792537 NCBI chr 1:142,174,648...142,183,884
Ensembl chr 1:142,174,648...142,183,884
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO
IBA
ISS
(MGI:MGI:3703139|PMID:16272347)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:16272347, PMID:21873635 GO_REF:0000024, MGI:MGI:3703139, RGD:13792537 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 ISO (MGI:MGI:5298334|PMID:21063107) RGD PMID:21063107 MGI:MGI:5298334 NCBI chr10:13,446,373...13,525,248
Ensembl chr10:13,451,624...13,515,448
JBrowse link
G Rac2 Rac family small GTPase 2 ISO (MGI:MGI:3655336|PMID:10843388) RGD PMID:10843388 MGI:MGI:3655336 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G RGD1311164 similar to DNA segment, Chr 6, Wayne State University 163, expressed IDA
IBA
PMID:25122211
PMID:21873635
UniProt
GO_Central
PMID:25122211, PMID:21873635 RGD:10047193, RGD:13792537 NCBI chr 4:159,483,089...159,518,387
Ensembl chr 4:159,483,131...159,515,447
JBrowse link
G Stxbp2 syntaxin binding protein 2 IMP RGD PMID:12482918 RGD:2312429 NCBI chr12:2,180,101...2,191,863
Ensembl chr12:2,180,150...2,191,175
JBrowse link
G Unc13d unc-13 homolog D IEA
ISO
GO_REF:0000107
(PMID:15548590)
Ensembl
RGD
PMID:15548590 GO_REF:0000107 NCBI chr10:104,613,907...104,628,664
Ensembl chr10:104,613,928...104,628,676
JBrowse link
regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pram1 PML-RARA regulated adaptor molecule 1 ISO MGI:MGI:3579812 (MGI:MGI:3525750|PMID:15572693) RGD PMID:15572693 MGI:MGI:3525750 NCBI chr 7:18,507,878...18,516,321
Ensembl chr 7:18,510,354...18,515,503
JBrowse link
G Syk spleen associated tyrosine kinase IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:4414596|PMID:19797524)
Ensembl
UniProt
RGD
PMID:19797524 GO_REF:0000024, GO_REF:0000107, MGI:MGI:4414596 NCBI chr17:12,614,311...12,669,568
Ensembl chr17:12,614,311...12,669,573
JBrowse link
serotonin secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule ISO (MGI:MGI:3721168|PMID:12874256) RGD PMID:12874256 MGI:MGI:3721168 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    immune system process 2838
      immune effector process 882
        leukocyte degranulation 90
          basophil degranulation + 1
          cytotoxic T cell degranulation + 3
          eosinophil degranulation + 7
          mast cell degranulation + 60
          natural killer cell degranulation + 11
          negative regulation of leukocyte degranulation + 12
          neutrophil degranulation + 23
          positive regulation of leukocyte degranulation + 40
          regulation of leukocyte degranulation + 63
Path 2
Term Annotations click to browse term
  biological_process 20017
    localization 6486
      establishment of localization 4918
        transport 4774
          export from cell 1071
            secretion by cell 1020
              exocytosis 414
                regulated exocytosis 279
                  leukocyte degranulation 90
                    basophil degranulation + 1
                    cytotoxic T cell degranulation + 3
                    eosinophil degranulation + 7
                    mast cell degranulation + 60
                    natural killer cell degranulation + 11
                    negative regulation of leukocyte degranulation + 12
                    neutrophil degranulation + 23
                    positive regulation of leukocyte degranulation + 40
                    regulation of leukocyte degranulation + 63
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.