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ONTOLOGY REPORT - ANNOTATIONS


Term:neutrophil degranulation
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Accession:GO:0043312 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
Synonyms:exact_synonym: neutrophil granule exocytosis
 related_synonym: heterophil degranulation


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neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa3 annexin A3 JBrowse link 14 14,371,921 14,426,503 RGD:1624291
G Myo1f myosin IF JBrowse link 7 18,440,742 18,491,448 RGD:1624291
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
G Stxbp2 syntaxin binding protein 2 JBrowse link 12 2,180,101 2,191,863 RGD:1600115
RGD:1624291
G Stxbp3 syntaxin binding protein 3 JBrowse link 2 211,595,763 211,638,756 RGD:1624291
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:8553828
RGD:1624291
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1624291
negative regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abr ABR activator of RhoGEF and GTPase JBrowse link 10 64,565,121 64,657,079 RGD:1624291
RGD:1600115
G Bcr BCR activator of RhoGEF and GTPase JBrowse link 20 14,421,250 14,546,406 RGD:1624291
positive regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd177 CD177 molecule JBrowse link 1 82,964,683 82,987,306 RGD:1624291
RGD:13792537
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:1624291
G Itgb2 integrin subunit beta 2 JBrowse link 20 11,777,773 11,815,647 RGD:1624291
G LOC100909620 CD177 antigen-like JBrowse link 1 81,555,412 81,560,629 RGD:13792537
G LOC100909700 CD177 antigen-like JBrowse link 1 81,609,177 81,627,763 RGD:13792537
G LOC100910565 CD177 antigen-like JBrowse link 1 81,548,679 81,551,288 RGD:13792537
G LOC100910611 CD177 antigen-like JBrowse link 1 81,564,683 81,584,541 RGD:13792537
G LOC100910953 CD177 antigen-like JBrowse link 1 82,815,709 82,820,487 RGD:13792537
G LOC102553892 CD177 antigen-like JBrowse link 1 82,947,303 82,952,884 RGD:13792537
G Ptafr platelet-activating factor receptor JBrowse link 5 150,746,284 150,775,675 RGD:10041060
G RGD1564380 similar to BC049730 protein JBrowse link 1 82,830,153 82,902,864 RGD:13792537
G RGD1565655 similar to BC049730 protein JBrowse link 1 81,592,004 81,597,637 RGD:13792537
regulation of neutrophil degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pram1 PML-RARA regulated adaptor molecule 1 JBrowse link 7 18,507,878 18,516,321 RGD:1624291
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      immune effector process 877
        leukocyte degranulation 89
          neutrophil degranulation 24
            negative regulation of neutrophil degranulation 2
            positive regulation of neutrophil degranulation 12
            regulation of neutrophil degranulation + 16
Path 2
Term Annotations click to browse term
  biological_process 19858
    localization 6457
      establishment of localization 4907
        transport 4764
          secretion 1258
            secretion by cell 1061
              exocytosis 426
                regulated exocytosis 294
                  leukocyte degranulation 89
                    neutrophil degranulation 24
                      negative regulation of neutrophil degranulation 2
                      positive regulation of neutrophil degranulation 12
                      regulation of neutrophil degranulation + 16
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.