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ONTOLOGY REPORT - ANNOTATIONS


Term:natural killer cell degranulation
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Accession:GO:0043320 term browser browse the term
Definition:The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.
Synonyms:exact_synonym: NK cell degranulation;   NK cell granule exocytosis;   natural killer cell granule exocytosis


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natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Coro1a coronin 1A JBrowse link 1 198,123,883 198,128,890 RGD:1624291
G Rab27a RAB27A, member RAS oncogene family JBrowse link 8 79,722,334 79,776,228 RGD:1624291
G Stx11 syntaxin 11 JBrowse link 1 7,039,160 7,064,870 RGD:1624291
G Unc13d unc-13 homolog D JBrowse link 10 104,613,907 104,628,664 RGD:1624291
RGD:1600115
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:1624291
G Vamp7 vesicle-associated membrane protein 7 JBrowse link 12 18,996,566 19,033,714 RGD:1624291
negative regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291
positive regulation of natural killer cell degranulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 JBrowse link 19 41,805,252 41,860,076 RGD:1624291
G Cd160 CD160 molecule JBrowse link 2 198,933,681 198,965,380 RGD:1624291
G Lamp1 lysosomal-associated membrane protein 1 JBrowse link 16 81,689,576 81,714,341 RGD:1624291
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    immune system process 2631
      immune effector process 849
        leukocyte degranulation 79
          natural killer cell degranulation 11
            negative regulation of natural killer cell degranulation 2
            positive regulation of natural killer cell degranulation 4
            regulation of natural killer cell degranulation + 5
Path 2
Term Annotations click to browse term
  biological_process 19439
    localization 6373
      establishment of localization 4900
        transport 4760
          export from cell 1220
            secretion by cell 1172
              exocytosis 408
                regulated exocytosis 285
                  leukocyte degranulation 79
                    natural killer cell degranulation 11
                      negative regulation of natural killer cell degranulation 2
                      positive regulation of natural killer cell degranulation 4
                      regulation of natural killer cell degranulation + 5
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.