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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of CD4-positive, alpha-beta T cell differentiation
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Accession:GO:0043372 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: positive regulation of CD4-positive T lymphocyte differentiation;   positive regulation of CD4-positive T-cell differentiation;   positive regulation of CD4-positive, alpha beta T lymphocyte differentiation;   up regulation of CD4-positive, alpha beta T cell differentiation;   upregulation of CD4-positive, alpha beta T cell differentiation
 narrow_synonym: activation of CD4-positive, alpha beta T cell differentiation;   stimulation of CD4-positive, alpha beta T cell differentiation
 related_synonym: positive regulation of CD4-positive, alpha beta T cell development


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positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD83 CD83 molecule JBrowse link 6 14,330,752 14,349,946 RGD:9068941
G NCKAP1L NCK associated protein 1 like JBrowse link 12 34,932,470 34,977,881 RGD:9068941
G SASH3 SAM and SH3 domain containing 3 JBrowse link X 129,207,049 129,222,342 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 133,959,365 133,975,729 RGD:9068941
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,402,652 49,417,029 RGD:9068941
G GIMAP5 GTPase, IMAP family member 5 JBrowse link 7 154,471,995 154,478,298 RGD:9068941
G IL2RG interleukin 2 receptor subunit gamma JBrowse link X 70,433,355 70,437,590 RGD:9068941
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 12 68,448,861 68,453,829 RGD:9068941
G LOC100977210 galectin-9 JBrowse link 17 29,623,398 29,642,959 RGD:9068941
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 71,930,148 71,948,779 RGD:9068941
G CCL19 C-C motif chemokine ligand 19 JBrowse link 9 35,334,353 35,336,108 RGD:9068941
G HLX H2.0 like homeobox JBrowse link 1 201,500,470 201,506,222 RGD:9068941
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 88,397,768 88,431,690 RGD:9068941
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2A 47,745,216 47,808,566 RGD:9068941
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MALT1 MALT1 paracaspase JBrowse link 18 55,395,462 55,473,574 RGD:9068941
G NFKBID NFKB inhibitor delta JBrowse link 19 41,553,727 41,565,216 RGD:9068941
G NFKBIZ NFKB inhibitor zeta JBrowse link 3 105,616,645 105,628,300 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 228,505,147 228,537,216 RGD:9068941
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL23A interleukin 23 subunit alpha JBrowse link 12 32,828,902 32,830,621 RGD:9068941
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL18 interleukin 18 JBrowse link 11 110,867,586 110,888,371 RGD:9068941
G IL4R interleukin 4 receptor JBrowse link 16 27,686,760 27,737,445 RGD:9068941
G IL6 interleukin 6 JBrowse link 7 23,027,560 23,032,419 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 228,505,147 228,537,216 RGD:9068941
G PRKCZ protein kinase C zeta JBrowse link 1 1,918,653 2,046,236 RGD:9068941
G RARA retinoic acid receptor alpha JBrowse link 17 17,156,923 17,205,451 RGD:9068941
G TNFSF4 TNF superfamily member 4 JBrowse link 1 152,391,450 152,699,026 RGD:9068941
positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYB MYB proto-oncogene, transcription factor JBrowse link 6 136,974,525 137,086,194 RGD:9068941
G SHB SH2 domain containing adaptor protein B JBrowse link 9 38,694,980 38,843,827 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12351
    immune system process 2027
      leukocyte activation 826
        lymphocyte activation 664
          T cell activation 464
            alpha-beta T cell activation 156
              CD4-positive, alpha-beta T cell activation 96
                CD4-positive, alpha-beta T cell differentiation 78
                  positive regulation of CD4-positive, alpha-beta T cell differentiation 27
                    positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 5
                    positive regulation of T-helper cell differentiation + 18
Path 2
Term Annotations click to browse term
  biological_process 12351
    developmental process 5690
      anatomical structure development 5315
        multicellular organism development 4860
          system development 4592
            immune system development 940
              hematopoietic or lymphoid organ development 883
                hemopoiesis 835
                  leukocyte differentiation 523
                    lymphocyte differentiation 350
                      T cell differentiation 263
                        alpha-beta T cell differentiation 113
                          CD4-positive, alpha-beta T cell differentiation 78
                            regulation of CD4-positive, alpha-beta T cell differentiation 46
                              positive regulation of CD4-positive, alpha-beta T cell differentiation 27
                                positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 5
                                positive regulation of T-helper cell differentiation + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.