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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of CD4-positive, alpha-beta T cell differentiation
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Accession:GO:0043372 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: positive regulation of CD4-positive T lymphocyte differentiation;   positive regulation of CD4-positive T-cell differentiation;   positive regulation of CD4-positive, alpha beta T lymphocyte differentiation;   up regulation of CD4-positive, alpha beta T cell differentiation;   upregulation of CD4-positive, alpha beta T cell differentiation
 narrow_synonym: activation of CD4-positive, alpha beta T cell differentiation;   stimulation of CD4-positive, alpha beta T cell differentiation
 related_synonym: positive regulation of CD4-positive, alpha beta T cell development


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positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd83 CD83 molecule JBrowse link NW_004955465 676,006 692,770 RGD:9068941
G Nckap1l NCK associated protein 1 like JBrowse link NW_004955458 1,733,799 1,785,591 RGD:9068941
G Sash3 SAM and SH3 domain containing 3 JBrowse link NW_004955473 5,224,635 5,237,066 RGD:9068941
G Socs1 suppressor of cytokine signaling 1 JBrowse link NW_004955442 7,321,337 7,323,109 RGD:9068941
G Tnfsf4 TNF superfamily member 4 JBrowse link NW_004955406 13,477,077 13,493,309 RGD:9068941
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link NW_004955545 1,504,656 1,519,954 RGD:9068941
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Foxp3 forkhead box P3 JBrowse link NW_004955543 731,707 742,606 RGD:9068941
G Il2rg interleukin 2 receptor subunit gamma JBrowse link NW_004955475 10,676,592 10,680,565 RGD:9068941
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ifng interferon gamma JBrowse link NW_004955458 14,643,333 14,648,020 RGD:9068941
G Lgals9 galectin 9 JBrowse link NW_004955481 5,234,125 5,249,564 RGD:9068941
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anxa1 annexin A1 JBrowse link NW_004955512 5,686,508 5,703,645 RGD:9068941
G Ccl19 C-C motif chemokine ligand 19 JBrowse link NW_004955472 1,444,598 1,446,488 RGD:9068941
G Hlx H2.0 like homeobox JBrowse link NW_004955520 2,937,131 2,941,170 RGD:9068941
G Ripk2 receptor interacting serine/threonine kinase 2 JBrowse link NW_004955417 6,669,675 6,698,142 RGD:9068941
G Socs5 suppressor of cytokine signaling 5 JBrowse link NW_004955441 13,593,342 13,657,389 RGD:9068941
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Malt1 MALT1 paracaspase JBrowse link NW_004955402 42,919,480 42,968,873 RGD:9068941
G Nfkbid NFKB inhibitor delta JBrowse link NW_004955468 2,680,934 2,688,797 RGD:9068941
G Nfkbiz NFKB inhibitor zeta JBrowse link NW_004955427 3,350,174 3,358,609 RGD:9068941
G Nlrp3 NLR family pyrin domain containing 3 JBrowse link NW_004955581 597,952 616,903 RGD:9068941
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il23a interleukin 23 subunit alpha JBrowse link NW_004955458 3,946,964 3,949,180 RGD:9068941
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il18 interleukin 18 JBrowse link NW_004955412 13,807,361 13,826,007 RGD:9068941
G Il4r interleukin 4 receptor JBrowse link NW_004955493 5,546,340 5,580,745 RGD:9068941
G Il6 interleukin 6 JBrowse link NW_004955410 25,079,835 25,084,390 RGD:9068941
G Nlrp3 NLR family pyrin domain containing 3 JBrowse link NW_004955581 597,952 616,903 RGD:9068941
G Prkcz protein kinase C zeta JBrowse link NW_004955486 8,947,579 9,021,702 RGD:9068941
G Rara retinoic acid receptor alpha JBrowse link NW_004955451 14,876,663 14,917,134 RGD:9068941
G Tnfsf4 TNF superfamily member 4 JBrowse link NW_004955406 13,477,077 13,493,309 RGD:9068941
positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Myb MYB proto-oncogene, transcription factor JBrowse link NW_004955439 1,523,516 1,560,185 RGD:9068941
G Shb SH2 domain containing adaptor protein B JBrowse link NW_004955419 28,423,354 28,555,948 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11826
    immune system process 1888
      leukocyte activation 787
        lymphocyte activation 639
          T cell activation 447
            alpha-beta T cell activation 151
              CD4-positive, alpha-beta T cell activation 94
                CD4-positive, alpha-beta T cell differentiation 77
                  positive regulation of CD4-positive, alpha-beta T cell differentiation 27
                    positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 4
                    positive regulation of T-helper cell differentiation + 18
Path 2
Term Annotations click to browse term
  biological_process 11826
    developmental process 5543
      anatomical structure development 5185
        multicellular organism development 4750
          system development 4493
            immune system development 909
              hematopoietic or lymphoid organ development 853
                hemopoiesis 807
                  leukocyte differentiation 505
                    lymphocyte differentiation 342
                      T cell differentiation 255
                        alpha-beta T cell differentiation 111
                          CD4-positive, alpha-beta T cell differentiation 77
                            regulation of CD4-positive, alpha-beta T cell differentiation 46
                              positive regulation of CD4-positive, alpha-beta T cell differentiation 27
                                positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 4
                                positive regulation of T-helper cell differentiation + 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.