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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of CD4-positive, alpha-beta T cell differentiation
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Accession:GO:0043372 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: positive regulation of CD4-positive T lymphocyte differentiation;   positive regulation of CD4-positive T-cell differentiation;   positive regulation of CD4-positive, alpha beta T lymphocyte differentiation;   up regulation of CD4-positive, alpha beta T cell differentiation;   upregulation of CD4-positive, alpha beta T cell differentiation
 narrow_synonym: activation of CD4-positive, alpha beta T cell differentiation;   stimulation of CD4-positive, alpha beta T cell differentiation
 related_synonym: positive regulation of CD4-positive, alpha beta T cell development


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positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD83 CD83 molecule JBrowse link 6 14,117,256 14,136,918 RGD:2290271
G NCKAP1L NCK associated protein 1 like JBrowse link 12 54,497,752 54,548,243 RGD:2290271
G SASH3 SAM and SH3 domain containing 3 JBrowse link X 129,779,949 129,795,201 RGD:2290271
G SOCS1 suppressor of cytokine signaling 1 JBrowse link 16 11,254,417 11,256,182 RGD:2290271
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
G ZBTB7B zinc finger and BTB domain containing 7B JBrowse link 1 155,002,628 155,018,523 RGD:2290271
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G FOXP3 forkhead box P3 JBrowse link X 49,250,436 49,264,932 RGD:2290271
G GIMAP5 GTPase, IMAP family member 5 JBrowse link 7 150,737,348 150,743,649 RGD:9068941
G IL2RG interleukin 2 receptor subunit gamma JBrowse link X 71,107,404 71,111,577 RGD:9068941
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:2290271
G LGALS9 galectin 9 JBrowse link 17 27,631,172 27,649,560 RGD:2290271
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ANXA1 annexin A1 JBrowse link 9 73,151,865 73,170,393 RGD:2290271
G CCL19 C-C motif chemokine ligand 19 JBrowse link 9 34,689,570 34,691,276 RGD:2290271
G CD80 CD80 molecule JBrowse link 3 119,524,293 119,559,614 RGD:2290271
G HLX H2.0 like homeobox JBrowse link 1 220,879,443 220,885,059 RGD:2290271
G RIPK2 receptor interacting serine/threonine kinase 2 JBrowse link 8 89,757,816 89,791,064 RGD:2290271
G SOCS5 suppressor of cytokine signaling 5 JBrowse link 2 46,698,960 46,763,129 RGD:2290271
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MALT1 MALT1 paracaspase JBrowse link 18 58,671,420 58,754,477 RGD:2290271
G MIR326 microRNA 326 JBrowse link 11 75,335,092 75,335,186 RGD:9068941
G NFKBID NFKB inhibitor delta JBrowse link 19 35,887,630 35,902,303 RGD:2290271
G NFKBIZ NFKB inhibitor zeta JBrowse link 3 101,827,990 101,861,022 RGD:2290271
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 247,416,163 247,448,823 RGD:2290271
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL12B interleukin 12B JBrowse link 5 159,314,780 159,330,487 RGD:2290271
G IL12RB1 interleukin 12 receptor subunit beta 1 JBrowse link 19 18,058,994 18,099,027 RGD:2290271
G IL23A interleukin 23 subunit alpha JBrowse link 12 56,334,159 56,340,410 RGD:2290271
G IL23R interleukin 23 receptor JBrowse link 1 67,138,639 67,259,979 RGD:2290271
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CD86 CD86 molecule JBrowse link 3 122,055,362 122,121,143 RGD:2290271
G IL18 interleukin 18 JBrowse link 11 112,143,251 112,164,104 RGD:2290271
G IL4R interleukin 4 receptor JBrowse link 16 27,313,668 27,364,778 RGD:2290271
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:9068941
G NLRP3 NLR family pyrin domain containing 3 JBrowse link 1 247,416,163 247,448,823 RGD:2290271
G PRKCZ protein kinase C zeta JBrowse link 1 2,050,411 2,185,399 RGD:2290271
G RARA retinoic acid receptor alpha JBrowse link 17 40,309,180 40,357,643 RGD:2290271
G TNFSF4 TNF superfamily member 4 JBrowse link 1 173,183,729 173,462,208 RGD:2290271
positive regulation of T-helper cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G MYB MYB proto-oncogene, transcription factor JBrowse link 6 135,181,308 135,219,172 RGD:2290271
G SHB SH2 domain containing adaptor protein B JBrowse link 9 37,915,898 38,069,227 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18534
    immune system process 3544
      leukocyte activation 1459
        lymphocyte activation 878
          T cell activation 560
            alpha-beta T cell activation 179
              CD4-positive, alpha-beta T cell activation 113
                CD4-positive, alpha-beta T cell differentiation 90
                  positive regulation of CD4-positive, alpha-beta T cell differentiation 34
                    positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 5
                    positive regulation of T-helper cell differentiation + 24
Path 2
Term Annotations click to browse term
  biological_process 18534
    developmental process 7411
      anatomical structure development 6814
        multicellular organism development 6283
          system development 5698
            immune system development 1202
              hematopoietic or lymphoid organ development 1135
                hemopoiesis 1087
                  leukocyte differentiation 623
                    lymphocyte differentiation 426
                      T cell differentiation 296
                        alpha-beta T cell differentiation 126
                          CD4-positive, alpha-beta T cell differentiation 90
                            regulation of CD4-positive, alpha-beta T cell differentiation 57
                              positive regulation of CD4-positive, alpha-beta T cell differentiation 34
                                positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 5
                                positive regulation of T-helper cell differentiation + 24
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.