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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of CD8-positive, alpha-beta T cell differentiation
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Accession:GO:0043376 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: regulation of CD8-positive T lymphocyte differentiation;   regulation of CD8-positive T-cell differentiation;   regulation of CD8-positive, alpha beta T lymphocyte differentiation
 related_synonym: regulation of CD8-positive, alpha-beta T cell development


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regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B ISO MGI:MGI:3817628 (MGI:MGI:3817343|PMID:18776904) RGD PMID:18776904 MGI:MGI:3817343 NCBI chr 2:188,704,989...188,719,674
Ensembl chr 2:188,704,687...188,718,704
JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Socs1 suppressor of cytokine signaling 1 ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:MGI:6140589|PMID:24880459)
UniProt
Ensembl
RGD
PMID:24880459 GO_REF:0000024, GO_REF:0000107, MGI:MGI:6140589 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B ISO (MGI:MGI:5446998|PMID:22730529), (MGI:MGI:6140589|PMID:24880459) RGD PMID:22730529, PMID:24880459 MGI:MGI:5446998, MGI:MGI:6140589 NCBI chr 2:188,704,989...188,719,674
Ensembl chr 2:188,704,687...188,718,704
JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta ISO (MGI:MGI:3772948|PMID:18258917) RGD PMID:18258917 MGI:MGI:3772948 NCBI chr19:37,127,508...37,171,075
Ensembl chr19:37,127,508...37,171,069
JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:73,393,854...73,399,448
Ensembl chr 1:73,393,850...73,399,579
JBrowse link
G Nckap1l NCK associated protein 1 like ISO
ISS
(MGI:MGI:3818191|PMID:19015308)
GO_REF:0000024
RGD
UniProt
PMID:19015308 GO_REF:0000024, MGI:MGI:3818191 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Runx1 RUNX family transcription factor 1 ISS
ISO
GO_REF:0000024
(MGI:MGI:3772948|PMID:18258917)
UniProt
RGD
PMID:18258917 GO_REF:0000024, MGI:MGI:3772948 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Runx3 RUNX family transcription factor 3 ISO (MGI:MGI:3772948|PMID:18258917) RGD PMID:18258917 MGI:MGI:3772948 NCBI chr 5:153,507,093...153,531,137
Ensembl chr 5:153,507,093...153,531,137
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    immune system process 2843
      leukocyte activation 1060
        lymphocyte activation 875
          T cell activation 524
            alpha-beta T cell activation 175
              CD8-positive, alpha-beta T cell activation 33
                CD8-positive, alpha-beta T cell differentiation 18
                  regulation of CD8-positive, alpha-beta T cell differentiation 7
                    negative regulation of CD8-positive, alpha-beta T cell differentiation 2
                    positive regulation of CD8-positive, alpha-beta T cell differentiation 5
Path 2
Term Annotations click to browse term
  biological_process 20028
    developmental process 6827
      anatomical structure development 6269
        multicellular organism development 5744
          system development 5280
            immune system development 1074
              hematopoietic or lymphoid organ development 1009
                hemopoiesis 957
                  leukocyte differentiation 598
                    lymphocyte differentiation 410
                      T cell differentiation 290
                        regulation of T cell differentiation 161
                          regulation of alpha-beta T cell differentiation 72
                            regulation of CD8-positive, alpha-beta T cell differentiation 7
                              negative regulation of CD8-positive, alpha-beta T cell differentiation 2
                              positive regulation of CD8-positive, alpha-beta T cell differentiation 5
paths to the root

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