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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of CD8-positive, alpha-beta T cell differentiation
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Accession:GO:0043377 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of CD8-positive, alpha-beta T cell differentiation;   downregulation of CD8-positive, alpha-beta T cell differentiation;   negative regulation of CD8-positive T lymphocyte differentiation;   negative regulation of CD8-positive T-cell differentiation;   negative regulation of CD8-positive, alpha beta T lymphocyte differentiation
 narrow_synonym: inhibition of CD8-positive, alpha-beta T cell differentiation
 related_synonym: negative regulation of CD8-positive, alpha-beta T cell development


show annotations for term's descendants       view all columns           Sort by:
 
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1600115
RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    immune system process 2798
      leukocyte activation 1045
        lymphocyte activation 862
          T cell activation 515
            alpha-beta T cell activation 171
              CD8-positive, alpha-beta T cell activation 32
                CD8-positive, alpha-beta T cell differentiation 17
                  negative regulation of CD8-positive, alpha-beta T cell differentiation 2
Path 2
Term Annotations click to browse term
  biological_process 19858
    developmental process 6735
      anatomical structure development 6181
        multicellular organism development 5638
          system development 5212
            immune system development 1054
              hematopoietic or lymphoid organ development 991
                hemopoiesis 939
                  leukocyte differentiation 582
                    lymphocyte differentiation 398
                      T cell differentiation 282
                        alpha-beta T cell differentiation 120
                          CD8-positive, alpha-beta T cell differentiation 17
                            regulation of CD8-positive, alpha-beta T cell differentiation 6
                              negative regulation of CD8-positive, alpha-beta T cell differentiation 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.