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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of CD8-positive, alpha-beta T cell differentiation
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Accession:GO:0043377 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of CD8-positive, alpha-beta T cell differentiation;   downregulation of CD8-positive, alpha-beta T cell differentiation;   negative regulation of CD8-positive T lymphocyte differentiation;   negative regulation of CD8-positive T-cell differentiation;   negative regulation of CD8-positive, alpha beta T lymphocyte differentiation
 narrow_synonym: inhibition of CD8-positive, alpha-beta T cell differentiation
 related_synonym: negative regulation of CD8-positive, alpha-beta T cell development


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negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Socs1 suppressor of cytokine signaling 1 JBrowse link 10 4,956,795 4,958,472 RGD:1600115
RGD:1624291
G Zbtb7b zinc finger and BTB domain containing 7B JBrowse link 2 188,704,989 188,719,674 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    immune system process 2693
      leukocyte activation 1009
        lymphocyte activation 829
          T cell activation 503
            alpha-beta T cell activation 168
              CD8-positive, alpha-beta T cell activation 32
                CD8-positive, alpha-beta T cell differentiation 17
                  negative regulation of CD8-positive, alpha-beta T cell differentiation 2
Path 2
Term Annotations click to browse term
  biological_process 19578
    developmental process 6697
      anatomical structure development 6155
        multicellular organism development 5623
          system development 5157
            immune system development 1046
              hematopoietic or lymphoid organ development 982
                hemopoiesis 930
                  leukocyte differentiation 575
                    lymphocyte differentiation 392
                      T cell differentiation 279
                        alpha-beta T cell differentiation 119
                          CD8-positive, alpha-beta T cell differentiation 17
                            regulation of CD8-positive, alpha-beta T cell differentiation 6
                              negative regulation of CD8-positive, alpha-beta T cell differentiation 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.