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Term:negative regulation of JUN kinase activity
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Accession:GO:0043508 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
Synonyms:exact_synonym: down regulation of JNK activity;   downregulation of JNK activity;   negative regulation of JUNK activity
 narrow_synonym: inhibition of JNK activity

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negative regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIDA axin interactor, dorsalization associated IDA (PMID:17681137) MGI PMID:17681137 NCBI chr 1:222,668,013...222,712,895
Ensembl chr 1:222,668,013...222,713,210
JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 IMP (PMID:24512202) UniProtKB PMID:24512202 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
JBrowse link
G DUSP10 dual specificity phosphatase 10 IDA
PMID:10391943, PMID:21873635 NCBI chr 1:221,701,424...221,742,091
Ensembl chr 1:221,701,424...221,742,089
JBrowse link
G DUSP19 dual specificity phosphatase 19 ISS BHF-UCL GO_REF:0000024 NCBI chr 2:183,078,747...183,100,008
Ensembl chr 2:183,078,559...183,100,008
JBrowse link
G GSTP1 glutathione S-transferase pi 1 IDA (PMID:16636664) BHF-UCL PMID:16636664 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
Ensembl chr11:67,583,742...67,586,656
JBrowse link
G HIPK3 homeodomain interacting protein kinase 3 ISS UniProtKB GO_REF:0000024 NCBI chr11:33,256,672...33,357,023
Ensembl chr11:33,256,672...33,357,023
JBrowse link
G MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 ISS UniProtKB GO_REF:0000024 NCBI chr11:45,885,651...45,906,465
Ensembl chr11:45,885,651...45,906,465
JBrowse link
G NPPA natriuretic peptide A IDA (PMID:22399583) UniProt PMID:22399583 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G PDCD4 programmed cell death 4 ISS UniProtKB GO_REF:0000024 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006
JBrowse link
G PTPN22 protein tyrosine phosphatase non-receptor type 22 IMP (PMID:23991106) UniProtKB PMID:23991106 NCBI chr 1:113,813,811...113,871,761
Ensembl chr 1:113,813,811...113,871,753
JBrowse link
G SERPINB3 serpin family B member 3 IMP (PMID:21383048) UniProtKB PMID:21383048 NCBI chr18:63,655,197...63,661,893
Ensembl chr18:63,655,197...63,661,893
JBrowse link
G SFRP1 secreted frizzled related protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:41,261,962...41,309,473
Ensembl chr 8:41,261,962...41,309,473
JBrowse link
G SFRP2 secreted frizzled related protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
JBrowse link
G SFRP5 secreted frizzled related protein 5 ISO (MGI:MGI:3839161|PMID:19300477) MGI PMID:19300477 MGI:MGI:3839161 NCBI chr10:97,766,751...97,771,999
Ensembl chr10:97,766,751...97,771,999
JBrowse link
G TP73 tumor protein p73 ISO (MGI:MGI:3574697|PMID:15483136) MGI PMID:15483136 MGI:MGI:3574697 NCBI chr 1:3,652,516...3,736,201
Ensembl chr 1:3,652,516...3,736,201
JBrowse link
G ZNF675 zinc finger protein 675 IDA (PMID:11751921) BHF-UCL PMID:11751921 NCBI chr19:23,652,801...23,687,212
Ensembl chr19:23,525,631...23,687,220
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18670
    cellular process 17686
      signal transduction 6573
        signal transduction by protein phosphorylation 1012
          MAPK cascade 1002
            negative regulation of MAPK cascade 194
              negative regulation of MAP kinase activity 87
                negative regulation of JUN kinase activity 16
Path 2
Term Annotations click to browse term
  biological_process 18670
    metabolic process 12302
      organic substance metabolic process 11737
        macromolecule metabolic process 10194
          protein metabolic process 6198
            protein modification process 4442
              cellular protein modification process 4442
                protein phosphorylation 2154
                  signal transduction by protein phosphorylation 1012
                    MAPK cascade 1002
                      regulation of MAPK cascade 791
                        regulation of stress-activated MAPK cascade 199
                          negative regulation of stress-activated MAPK cascade 52
                            negative regulation of JNK cascade 41
                              negative regulation of JUN kinase activity 16
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.