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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of DNA damage response, signal transduction by p53 class mediator
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Accession:GO:0043517 term browser browse the term
Definition:Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Synonyms:exact_synonym: positive regulation of p53 induced by DNA damage response;   up regulation of DNA damage response, signal transduction by p53 class mediator;   upregulation of DNA damage response, signal transduction by p53 class mediator
 narrow_synonym: activation of DNA damage response, signal transduction by p53 class mediator;   stimulation of DNA damage response, signal transduction by p53 class mediator


show annotations for term's descendants           Sort by:
 
positive regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD1 ankyrin repeat domain 1 IEA Ensembl GO_REF:0000107 NCBI chr14:102,603,777...102,612,857
Ensembl chr14:102,603,777...102,612,839
JBrowse link
G ATM ATM serine/threonine kinase IEA Ensembl GO_REF:0000107 NCBI chr 9:36,620,656...36,759,555
Ensembl chr 9:36,620,658...36,759,554
JBrowse link
G ATR ATR serine/threonine kinase IEA Ensembl GO_REF:0000107 NCBI chr13:83,175,515...83,289,986
Ensembl chr13:83,174,824...83,289,923
JBrowse link
G DDX5 DEAD-box helicase 5 IEA Ensembl GO_REF:0000107 NCBI chr12:14,571,712...14,580,740
Ensembl chr12:14,571,310...14,601,576
JBrowse link
G EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 IEA Ensembl
InterPro
GO_REF:0000002, GO_REF:0000107 NCBI chr 7:5,368,341...5,390,665 JBrowse link
G HIC1 HIC ZBTB transcriptional repressor 1 ISO (MGI:MGI:5297787|PMID:16269335) UniProtKB PMID:16269335 MGI:MGI:5297787 NCBI chr12:48,167,861...48,172,540
Ensembl chr12:48,168,766...48,171,635
JBrowse link
G P14ARF p14ARF protein ISO (PMID:9529249) BHF-UCL PMID:9529249 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,774,496...200,798,854
JBrowse link
G PLA2R1 phospholipase A2 receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr15:66,899,783...67,018,608
Ensembl chr15:66,898,508...67,001,163
JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 ISO (MGI:MGI:2679929|PMID:14500851)
(PMID:15102863)
UniProtKB PMID:14500851, PMID:15102863 MGI:MGI:2679929 NCBI chr 1:161,184,458...161,188,138
Ensembl chr 1:161,182,868...161,188,164
JBrowse link
G SPRED1 sprouty related EVH1 domain containing 1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:132,903,103...133,016,725
Ensembl chr 1:132,902,304...133,016,467
JBrowse link
G SPRED2 sprouty related EVH1 domain containing 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:76,527,646...76,649,652
Ensembl chr 3:76,523,589...76,649,650
JBrowse link
G SPRED3 sprouty related EVH1 domain containing 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:47,302,211...47,312,034
Ensembl chr 6:47,302,055...47,309,180
JBrowse link
positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RPL26 ribosomal protein L26 IEA Ensembl GO_REF:0000107 NCBI chr12:53,548,313...53,553,453
Ensembl chr12:53,548,321...53,553,451
JBrowse link
G ZNF385A zinc finger protein 385A IEA Ensembl GO_REF:0000107 NCBI chr 5:19,560,317...19,583,254
Ensembl chr 5:19,560,317...19,583,221
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    positive regulation of biological process 6187
      positive regulation of cellular process 5709
        positive regulation of response to DNA damage stimulus 114
          positive regulation of DNA damage response, signal transduction by p53 class mediator 14
            positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 2
Path 2
Term Annotations click to browse term
  biological_process 16524
    biological regulation 11994
      regulation of biological process 11420
        regulation of cellular process 10970
          signal transduction 5920
            intracellular signal transduction 2481
              signal transduction in response to DNA damage 96
                DNA damage response, signal transduction by p53 class mediator 69
                  regulation of DNA damage response, signal transduction by p53 class mediator 35
                    positive regulation of DNA damage response, signal transduction by p53 class mediator 14
                      positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.