Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA damage response, signal transduction by p53 class mediator
go back to main search page
Accession:GO:0043518 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Synonyms:exact_synonym: down regulation of DNA damage response, signal transduction by p53 class mediator;   downregulation of DNA damage response, signal transduction by p53 class mediator;   negative regulation of p53 induced by DNA damage response
 narrow_synonym: inhibition of DNA damage response, signal transduction by p53 class mediator


GViewer not supported for chinchilla.
show annotations for term's descendants           Sort by:
 
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) ISO (MGI:MGI:3690285|PMID:17045821)
(PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chrNW_004955422:11,106,061...11,189,951 JBrowse link
G Cd74 CD74 molecule ISO (PMID:17045821)
(MGI:MGI:3690285|PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chrNW_004955415:4,129,151...4,138,336 JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A ISO (MGI:MGI:5318016|PMID:20736167) BHF-UCL PMID:20736167 MGI:MGI:5318016 NCBI chrNW_004955407:36,456,628...36,588,940 JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 ISO (MGI:MGI:4838949|PMID:20167603) UniProtKB PMID:20167603 MGI:MGI:4838949 NCBI chrNW_004955406:42,190,043...42,199,323 JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:17805299) BHF-UCL PMID:17805299 NCBI chrNW_004955452:3,044,042...3,104,650 JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO (PMID:29295817) UniProtKB PMID:29295817 NCBI chrNW_004955449:13,834,561...13,875,864 JBrowse link
G Mdm2 MDM2 proto-oncogene ISO (PMID:10360174), (PMID:9529249) BHF-UCL PMID:9529249, PMID:10360174 NCBI chrNW_004955458:15,264,028...15,287,290 JBrowse link
G Mif macrophage migration inhibitory factor ISO (MGI:MGI:3690285|PMID:17045821)
(PMID:17045821)
BHF-UCL PMID:17045821 MGI:MGI:3690285 NCBI chrNW_004955455:8,367,566...8,368,460 JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 ISO (PMID:16023600) UniProtKB PMID:16023600 NCBI chrNW_004955490:7,825,202...7,832,347 JBrowse link
G Pttg1ip PTTG1 interacting protein ISO (PMID:24506068) MGI PMID:24506068 NCBI chrNW_004955407:41,753,855...41,769,107 JBrowse link
G Senp2 SUMO specific peptidase 2 ISO (MGI:MGI:5433829|PMID:21183956) MGI PMID:21183956 MGI:MGI:5433829 NCBI chrNW_004955420:21,969,537...22,005,094 JBrowse link
G Sirt1 sirtuin 1 ISO (PMID:11672523) BHF-UCL PMID:11672523 NCBI chrNW_004955425:20,280,725...20,307,663 JBrowse link
G Snai1 snail family transcriptional repressor 1 ISO (PMID:15314165) BHF-UCL PMID:15314165 NCBI chrNW_004955445:8,232,084...8,237,893 JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:15314165) BHF-UCL PMID:15314165 NCBI chrNW_004955454:8,759,860...8,763,603 JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17690110) BHF-UCL PMID:17690110 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 ISO (MGI:MGI:5050389|PMID:20817677) MGI PMID:20817677 MGI:MGI:5050389 NCBI chrNW_004955532:3,604,720...3,615,112 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11862
    negative regulation of biological process 4623
      negative regulation of cellular process 4225
        negative regulation of response to DNA damage stimulus 73
          negative regulation of DNA damage response, signal transduction by p53 class mediator 16
            negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1
Path 2
Term Annotations click to browse term
  biological_process 11862
    biological regulation 8697
      regulation of biological process 8250
        regulation of cellular process 7832
          signal transduction 3673
            intracellular signal transduction 1974
              signal transduction in response to DNA damage 89
                DNA damage response, signal transduction by p53 class mediator 65
                  regulation of DNA damage response, signal transduction by p53 class mediator 33
                    negative regulation of DNA damage response, signal transduction by p53 class mediator 16
                      negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.