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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of DNA damage response, signal transduction by p53 class mediator
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Accession:GO:0043518 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Synonyms:exact_synonym: down regulation of DNA damage response, signal transduction by p53 class mediator;   downregulation of DNA damage response, signal transduction by p53 class mediator;   negative regulation of p53 induced by DNA damage response
 narrow_synonym: inhibition of DNA damage response, signal transduction by p53 class mediator


show annotations for term's descendants           Sort by:
 
negative regulation of DNA damage response, signal transduction by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule (Indian blood group) ISO
IEA
(PMID:17045821)
GO_REF:0000107
(MGI:MGI:3690285|PMID:17045821)
RGD
Ensembl
PMID:17045821 GO_REF:0000107, MGI:MGI:3690285 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd74 CD74 molecule ISO
IBA
ISS
(MGI:MGI:3690285|PMID:17045821)
PMID:21873635
GO_REF:0000024
(PMID:17045821)
RGD
BHF-UCL
PMID:17045821, PMID:21873635 GO_REF:0000024, MGI:MGI:3690285, RGD:13792537 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A ISO (MGI:MGI:5318016|PMID:20736167) RGD PMID:20736167 MGI:MGI:5318016 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G Dyrk3 dual specificity tyrosine phosphorylation regulated kinase 3 IEA
ISO
GO_REF:0000107
(MGI:MGI:4838949|PMID:20167603)
Ensembl
RGD
PMID:20167603 GO_REF:0000107, MGI:MGI:4838949 NCBI chr13:47,906,230...47,916,877
Ensembl chr13:47,906,231...47,916,877
JBrowse link
G Kdm1a lysine demethylase 1A ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:154,909,003...154,965,171
Ensembl chr 5:154,909,003...154,965,171
JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 ISO
ISS
(PMID:29295817)
GO_REF:0000024
RGD
UniProt
PMID:29295817 GO_REF:0000024 NCBI chr 3:46,284,961...46,325,230
Ensembl chr 3:46,286,712...46,324,057
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO (PMID:10360174), (PMID:9529249) RGD PMID:9529249, PMID:10360174 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mif macrophage migration inhibitory factor ISO (MGI:MGI:3690285|PMID:17045821)
(PMID:17045821)
RGD PMID:17045821 MGI:MGI:3690285 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 ISO
IEA
ISS
(PMID:16023600)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16023600 GO_REF:0000024, GO_REF:0000107 NCBI chr  X:112,323,188...112,328,642
Ensembl chr  X:112,323,187...112,328,642
JBrowse link
G Pttg1ip PTTG1 interacting protein ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,746,369...11,764,097
Ensembl chr20:11,746,370...11,764,233
JBrowse link
G Senp2 SUMO specific peptidase 2 ISO (MGI:MGI:5433829|PMID:21183956) RGD PMID:21183956 MGI:MGI:5433829 NCBI chr11:82,627,973...82,664,702
Ensembl chr11:82,630,436...82,664,630
JBrowse link
G Sirt1 sirtuin 1 ISO
IEA
(PMID:11672523)
GO_REF:0000107
RGD
Ensembl
PMID:11672523 GO_REF:0000107 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Snai1 snail family transcriptional repressor 1 ISO (PMID:15314165) RGD PMID:15314165 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (PMID:17690110) RGD PMID:17690110 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pcbp4 poly(rC) binding protein 4 ISO (MGI:MGI:5050389|PMID:20817677) RGD PMID:20817677 MGI:MGI:5050389 NCBI chr 8:115,154,848...115,165,706
Ensembl chr 8:115,155,470...115,165,706
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    negative regulation of biological process 5710
      negative regulation of cellular process 5158
        negative regulation of response to DNA damage stimulus 77
          negative regulation of DNA damage response, signal transduction by p53 class mediator 16
            negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of cellular process 12570
          signal transduction 7015
            intracellular signal transduction 2615
              signal transduction in response to DNA damage 95
                DNA damage response, signal transduction by p53 class mediator 68
                  regulation of DNA damage response, signal transduction by p53 class mediator 35
                    negative regulation of DNA damage response, signal transduction by p53 class mediator 16
                      negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.