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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated transcription in response to stress
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Accession:GO:0043620 term browser browse the term
Definition:Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Synonyms:exact_synonym: regulation of DNA-dependent transcription in response to stress


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regulation of DNA-templated transcription in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCLAF1 BCL2 associated transcription factor 1 ISO (PMID:17938203) UniProtKB PMID:17938203 NCBI chr 6:134,023,195...134,054,507
Ensembl chr 6:138,115,451...138,137,108
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO (PMID:26649771) UniProtKB PMID:26649771 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RGS14 regulator of G protein signaling 14 ISO (MGI:MGI:5284798|PMID:15520006) UniProtKB PMID:15520006 MGI:MGI:5284798 NCBI chr 5:172,659,323...172,674,084
Ensembl chr 5:179,721,876...179,739,453
JBrowse link
G TCIM transcriptional and immune response regulator ISO (PMID:17603013) UniProtKB PMID:17603013 NCBI chr 8:39,347,441...39,348,795
Ensembl chr 8:36,855,045...36,855,365
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:21113145) ParkinsonsUK-UCL PMID:21113145 NCBI chr 1:58,042,794...58,045,536 JBrowse link
G NCK1 NCK adaptor protein 1 ISO (PMID:16835242)
(MGI:MGI:5613475|PMID:16835242)
ParkinsonsUK-UCL PMID:16835242 MGI:MGI:5613475 NCBI chr 3:133,902,463...133,990,414
Ensembl chr 3:141,427,870...141,451,444
JBrowse link
G NCK2 NCK adaptor protein 2 ISO (MGI:MGI:5613475|PMID:16835242) ParkinsonsUK-UCL PMID:16835242 MGI:MGI:5613475 NCBI chr2A:95,939,197...96,089,163
Ensembl chr2A:106,898,547...106,976,363
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO (MGI:MGI:5605960|PMID:11381086) ParkinsonsUK-UCL PMID:11381086 MGI:MGI:5605960 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 ISO (MGI:MGI:3840374|PMID:19328063) ParkinsonsUK-UCL PMID:19328063 MGI:MGI:3840374 NCBI chr12:38,986,844...39,010,307
Ensembl chr12:39,879,951...39,902,303
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (PMID:22735262) BHF-UCL PMID:22735262 NCBI chr 6:137,134,142...137,136,550 JBrowse link
G HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor ISO (PMID:11641274) UniProtKB PMID:11641274 NCBI chr10:97,135,751...97,148,378
Ensembl chr10:100,616,208...100,628,470
JBrowse link
G SIRT2 sirtuin 2 ISO (PMID:24681946) UniProtKB PMID:24681946 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799
JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO (PMID:11641274) UniProtKB PMID:11641274 NCBI chr 3:10,077,630...10,089,499
Ensembl chr 3:10,430,143...10,440,234
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 ISO (PMID:26159920) UniProtKB PMID:26159920 NCBI chr10:116,221,747...116,248,692
Ensembl chr10:119,643,963...119,665,964
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 ISO (PMID:9499401) UniProtKB PMID:9499401 NCBI chr19:14,078,201...14,081,884
Ensembl chr19:14,922,389...14,926,268
JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A ISO (PMID:9499401) UniProtKB PMID:9499401 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G IMPACT impact RWD domain protein ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chr18:17,678,297...17,720,348
Ensembl chr18:21,299,213...21,322,868
JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:6101031|PMID:29149604) UniProt PMID:29149604 MGI:MGI:6101031 NCBI chr17:9,476,482...9,489,661
Ensembl chr17:9,657,847...9,671,040
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEDD4 NEDD4 E3 ubiquitin protein ligase ISO (PMID:17996703) BHF-UCL PMID:17996703 NCBI chr15:34,798,880...34,963,823
Ensembl chr15:53,118,411...53,283,076
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 ISO (PMID:24939851) ParkinsonsUK-UCL PMID:24939851 NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150
JBrowse link
G ATF4 activating transcription factor 4 ISO (MGI:MGI:5433837|PMID:21113145), (MGI:MGI:5613480|PMID:12871976)
(PMID:21113145)
(PMID:12871976)
ParkinsonsUK-UCL PMID:12871976, PMID:21113145 MGI:MGI:5433837, MGI:MGI:5613480 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
JBrowse link
G ATF6 activating transcription factor 6 ISO (PMID:11163209), (PMID:11256944), (PMID:16469704) ParkinsonsUK-UCL PMID:11163209, PMID:11256944, PMID:16469704 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725
JBrowse link
G ATF6B activating transcription factor 6 beta ISO (PMID:11256944) ParkinsonsUK-UCL PMID:11256944 NCBI chr 6:31,762,161...31,775,136
Ensembl chr 6:32,643,124...32,655,617
JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO (PMID:15775988) ParkinsonsUK-UCL PMID:15775988 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 ISO (MGI:MGI:5616321|PMID:15665855) ParkinsonsUK-UCL PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chr11:46,236,384...46,280,145
Ensembl chr11:46,788,561...46,830,246
JBrowse link
G CREB3L3 cAMP responsive element binding protein 3 like 3 ISO (PMID:16469704)
(MGI:MGI:5616319|PMID:16469704)
ParkinsonsUK-UCL PMID:16469704 MGI:MGI:5616319 NCBI chr19:3,176,863...3,194,294
Ensembl chr19:4,127,597...4,144,300
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO PMID:8657121
(PMID:15775988)
(MGI:MGI:3525819|PMID:15601821)
(PMID:22761832)
(PMID:15322075), (PMID:24939851)
ParkinsonsUK-UCL PMID:8657121, PMID:15322075, PMID:15601821, PMID:15775988, PMID:22761832, PMID:24939851 MGI:MGI:3525819, RGD:1599740 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 ISO (PMID:11163209) ParkinsonsUK-UCL PMID:11163209 NCBI chr  X:14,470,268...14,529,854
Ensembl chr  X:21,825,780...21,883,550
JBrowse link
G TP53 tumor protein p53 ISO (MGI:MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:MGI:5621265 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 ISO (PMID:10747973), (PMID:12659875), (PMID:12665592), (PMID:15016915), (PMID:25963659), (PMID:26754925), (PMID:7760831), (PMID:9499401) UniProtKB PMID:7760831, PMID:9499401, PMID:10747973, PMID:12659875, PMID:12665592, PMID:15016915, PMID:25963659, PMID:26754925 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha ISO (PMID:19652095), (PMID:24681946)
(PMID:22735262)
BHF-UCL PMID:19652095, PMID:22735262, PMID:24681946 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO (PMID:24844779) BHF-UCL PMID:24844779 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G NOTCH1 notch receptor 1 ISO (MGI:MGI:5319604|PMID:18299578) UniProtKB PMID:18299578 MGI:MGI:5319604 NCBI chr 9:107,568,670...107,621,032
Ensembl chr 9:136,544,639...136,598,740
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region ISO (PMID:23303788) UniProtKB PMID:23303788 NCBI chr 4:20,719,548...20,835,439
Ensembl chr 4:25,995,263...26,107,683
JBrowse link
G TP53 tumor protein p53 ISO (MGI:MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:MGI:4867601 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
G VEGFA vascular endothelial growth factor A ISO (PMID:19652095) BHF-UCL PMID:19652095 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO (PMID:21113145)
PMID:23392669
ParkinsonsUK-UCL PMID:21113145, PMID:23392669 RGD:10047168 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
JBrowse link
G CHD6 chromodomain helicase DNA binding protein 6 ISO (PMID:16314513) UniProtKB PMID:16314513 NCBI chr20:37,744,012...37,953,593
Ensembl chr20:38,839,685...38,999,501
JBrowse link
G MT3 metallothionein 3 ISO (PMID:18554677) UniProtKB PMID:18554677 NCBI chr16:36,875,919...36,877,558 JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO PMID:16314513 UniProt PMID:16314513 RGD:8655528 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G SESN2 sestrin 2 ISO (PMID:23274085) UniProtKB PMID:23274085 NCBI chr 1:27,518,248...27,541,264
Ensembl chr 1:28,555,072...28,577,931
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCN1 GCN1 activator of EIF2AK4 ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chr12:117,702,791...117,769,894
Ensembl chr12:121,078,302...121,140,829
JBrowse link
G KLF2 Kruppel like factor 2 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chr19:15,812,506...15,815,244 JBrowse link
G MAPK7 mitogen-activated protein kinase 7 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chr17:31,729,429...31,736,216
Ensembl chr17:36,894,146...36,899,969
JBrowse link
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:4820675|PMID:20385086), (MGI:MGI:6107583|PMID:11342101), (MGI:MGI:6316451|PMID:10601325) UniProt PMID:10601325, PMID:11342101, PMID:20385086 MGI:MGI:4820675, MGI:MGI:6107583, MGI:MGI:6316451 NCBI chr17:9,476,482...9,489,661
Ensembl chr17:9,657,847...9,671,040
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chr2B:64,509,446...64,544,600
Ensembl chr2B:182,214,116...182,248,085
JBrowse link
G TP53 tumor protein p53 ISO (MGI:MGI:5883206|PMID:22262176)
(PMID:30089260)
CAFA
ARUK-UCL
PMID:22262176, PMID:30089260 MGI:MGI:5883206 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 ISO (PMID:30089260) ARUK-UCL PMID:30089260 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BACH1 BTB domain and CNC homolog 1 ISO (PMID:12511571) UniProtKB PMID:12511571 NCBI chr21:15,738,343...16,036,760
Ensembl chr21:29,126,107...29,173,835
JBrowse link
G EGR1 early growth response 1 ISO (MGI:MGI:3847400|PMID:18323529) MGI PMID:18323529 MGI:MGI:3847400 NCBI chr 5:133,845,305...133,849,291
Ensembl chr 5:139,975,635...139,979,260
JBrowse link
G STOX1 storkhead box 1 ISO (PMID:24738702) UniProtKB PMID:24738702 NCBI chr10:65,304,649...65,359,501
Ensembl chr10:67,882,654...67,894,039
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 ISO (PMID:24434510) MGI PMID:24434510 NCBI chr10:94,192,920...94,204,400
Ensembl chr10:97,686,121...97,697,238
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator ISO (PMID:8089148) BHF-UCL PMID:8089148 NCBI chr 1:126,160,017...126,226,222
Ensembl chr 1:129,809,431...129,875,629
JBrowse link
G EPAS1 endothelial PAS domain protein 1 NOT ISO (MGI:MGI:2681387|PMID:14608355)
(MGI:MGI:3703197|PMID:17284606)
(MGI:MGI:2667513|PMID:12832481)
MGI PMID:12832481, PMID:14608355, PMID:17284606 MGI:MGI:2667513, MGI:MGI:2681387, MGI:MGI:3703197 NCBI chr2A:46,403,411...46,492,734
Ensembl chr2A:47,332,308...47,421,560
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO (MGI:MGI:2667513|PMID:12832481)
(PMID:8089148), (PMID:8387214)
RGD
MGI
BHF-UCL
PMID:8089148, PMID:8387214, PMID:12832481, PMID:18614764 MGI:MGI:2667513, RGD:2301848 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885
JBrowse link
G HMOX1 heme oxygenase 1 ISO PMID:17430897 BHF-UCL PMID:17430897 RGD:8553479 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063
JBrowse link
G SIN3A SIN3 transcription regulator family member A ISO RGD PMID:18945670 RGD:2306468 NCBI chr15:54,285,587...54,371,376
Ensembl chr15:73,881,500...73,966,506
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 1:130,533,508...130,537,866
Ensembl chr 1:134,141,969...134,145,850
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 ISO (MGI:MGI:5294291|PMID:18243098) UniProtKB PMID:18243098 MGI:MGI:5294291 NCBI chr11:120,446,352...120,478,207 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12527
    cellular process 11621
      cellular response to stimulus 5309
        cellular response to stress 1698
          regulation of DNA-templated transcription in response to stress 52
            regulation of transcription from RNA polymerase II promoter in response to stress + 48
Path 2
Term Annotations click to browse term
  biological_process 12527
    metabolic process 7963
      cellular metabolic process 7311
        cellular aromatic compound metabolic process 3868
          nucleobase-containing compound metabolic process 3692
            nucleic acid metabolic process 3389
              RNA metabolic process 3007
                RNA biosynthetic process 2445
                  nucleic acid-templated transcription 2438
                    transcription, DNA-templated 2430
                      regulation of transcription, DNA-templated 2355
                        regulation of DNA-templated transcription in response to stress 52
                          regulation of transcription from RNA polymerase II promoter in response to stress + 48
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.