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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated transcription in response to stress
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Accession:GO:0043620 term browser browse the term
Definition:Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Synonyms:exact_synonym: regulation of DNA-dependent transcription in response to stress


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regulation of DNA-templated transcription in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bclaf1 BCL2 associated transcription factor 1 ISO (PMID:17938203) UniProtKB PMID:17938203 NCBI chrNW_004955439:608,849...641,005 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO (PMID:26649771) UniProtKB PMID:26649771 NCBI chrNW_004955422:19,602,930...19,612,263 JBrowse link
G Rgs14 regulator of G protein signaling 14 ISO (MGI:MGI:5284798|PMID:15520006) UniProtKB PMID:15520006 MGI:MGI:5284798 NCBI chrNW_004955408:29,602,654...29,616,793 JBrowse link
G Tcim transcriptional and immune response regulator ISO (PMID:17603013) UniProtKB PMID:17603013 NCBI chrNW_004955536:2,786,384...2,786,988 JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:21113145) ParkinsonsUK-UCL PMID:21113145 NCBI chrNW_004955464:1,107,598...1,110,326 JBrowse link
G Nck1 NCK adaptor protein 1 ISO (PMID:16835242)
(MGI:MGI:5613475|PMID:16835242)
ParkinsonsUK-UCL PMID:16835242 MGI:MGI:5613475 NCBI chrNW_004955501:1,867,956...1,963,091 JBrowse link
G Nck2 NCK adaptor protein 2 ISO (MGI:MGI:5613475|PMID:16835242) ParkinsonsUK-UCL PMID:16835242 MGI:MGI:5613475 NCBI chrNW_004955470:10,487,962...10,593,046 JBrowse link
G Ppp1r15a protein phosphatase 1 regulatory subunit 15A ISO (MGI:MGI:5605960|PMID:11381086) ParkinsonsUK-UCL PMID:11381086 MGI:MGI:5605960 NCBI chrNW_004955559:1,750,227...1,753,607 JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 ISO (MGI:MGI:3840374|PMID:19328063) ParkinsonsUK-UCL PMID:19328063 MGI:MGI:3840374 NCBI chrNW_004955547:335,344...358,503 JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (PMID:22735262) BHF-UCL PMID:22735262 NCBI chrNW_004955436:20,370,950...20,372,677 JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor ISO (PMID:11641274) UniProtKB PMID:11641274 NCBI chrNW_004955485:9,592,106...9,602,019 JBrowse link
G Sirt2 sirtuin 2 ISO (PMID:24681946) UniProtKB PMID:24681946 NCBI chrNW_004955468:626,365...644,441 JBrowse link
G Vhl von Hippel-Lindau tumor suppressor ISO (PMID:11641274) UniProtKB PMID:11641274 NCBI chrNW_004955561:1,573,525...1,578,295 JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 ISO (PMID:26159920) UniProtKB PMID:26159920 NCBI chrNW_004955551:446,322...468,329 JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 ISO (PMID:9499401) UniProtKB PMID:9499401 NCBI chrNW_004955415:33,098,503...33,102,125 JBrowse link
G Impact impact RWD domain protein ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chrNW_004955402:12,752,748...12,781,238 JBrowse link
G Nfe2l1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:6101031|PMID:29149604) UniProt PMID:29149604 MGI:MGI:6101031 NCBI chrNW_004955451:13,088,680...13,099,839 JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO (PMID:17996703) BHF-UCL PMID:17996703 NCBI chrNW_004955409:183,645...281,252 JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 ISO (PMID:24939851) ParkinsonsUK-UCL PMID:24939851 NCBI chrNW_004955406:4,875,672...4,889,173 JBrowse link
G Atf4 activating transcription factor 4 ISO (PMID:21113145)
(MGI:MGI:5433837|PMID:21113145), (MGI:MGI:5613480|PMID:12871976)
(PMID:12871976)
ParkinsonsUK-UCL PMID:12871976, PMID:21113145 MGI:MGI:5433837, MGI:MGI:5613480 NCBI chrNW_004955413:25,406,589...25,408,727 JBrowse link
G Atf6 activating transcription factor 6 ISO (PMID:11163209), (PMID:11256944), (PMID:16469704) ParkinsonsUK-UCL PMID:11163209, PMID:11256944, PMID:16469704 NCBI chrNW_004955462:14,352,956...14,553,299 JBrowse link
G Atf6b activating transcription factor 6 beta ISO (PMID:11256944) ParkinsonsUK-UCL PMID:11256944 NCBI chrNW_004955437:582,083...592,026 JBrowse link
G Cebpb CCAAT enhancer binding protein beta ISO (PMID:15775988) ParkinsonsUK-UCL PMID:15775988 NCBI chrNW_004955445:8,060,432...8,061,289 JBrowse link
G Creb3l1 cAMP responsive element binding protein 3 like 1 ISO (MGI:MGI:5616321|PMID:15665855) ParkinsonsUK-UCL PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chrNW_004955422:1,702,131...1,734,603 JBrowse link
G Creb3l3 cAMP responsive element binding protein 3 like 3 ISO (PMID:16469704)
(MGI:MGI:5616319|PMID:16469704)
ParkinsonsUK-UCL PMID:16469704 MGI:MGI:5616319 NCBI chrNW_004955495:4,651,086...4,670,852 JBrowse link
G Ddit3 DNA damage inducible transcript 3 ISO (PMID:22761832)
(PMID:15775988)
(PMID:15322075), (PMID:24939851)
(MGI:MGI:3525819|PMID:15601821)
PMID:8657121
ParkinsonsUK-UCL PMID:8657121, PMID:15322075, PMID:15601821, PMID:15775988, PMID:22761832, PMID:24939851 MGI:MGI:3525819, RGD:1599740 NCBI chrNW_004955458:5,232,979...5,238,513 JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chrNW_004955424:210,867...279,267 JBrowse link
G Mbtps2 membrane bound transcription factor peptidase, site 2 ISO (PMID:11163209) ParkinsonsUK-UCL PMID:11163209 NCBI chrNW_004955509:2,185,054...2,222,497 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:MGI:5621265 NCBI chrNW_004955467:9,241,391...9,256,716 JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 ISO (PMID:10747973), (PMID:12659875), (PMID:12665592), (PMID:15016915), (PMID:25963659), (PMID:26754925), (PMID:7760831), (PMID:9499401) UniProtKB PMID:7760831, PMID:9499401, PMID:10747973, PMID:12659875, PMID:12665592, PMID:15016915, PMID:25963659, PMID:26754925 NCBI chrNW_004955454:2,907,265...2,932,352 JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (PMID:22735262)
(PMID:19652095), (PMID:24681946)
BHF-UCL PMID:19652095, PMID:22735262, PMID:24681946 NCBI chrNW_004955466:8,000,311...8,022,497 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO (PMID:24844779) BHF-UCL PMID:24844779 NCBI chrNW_004955403:19,510,122...19,536,428 JBrowse link
G Notch1 notch receptor 1 ISO (MGI:MGI:5319604|PMID:18299578) UniProtKB PMID:18299578 MGI:MGI:5319604 NCBI chrNW_004955513:4,225,939...4,264,875 JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (PMID:23303788) UniProtKB PMID:23303788 NCBI chrNW_004955443:18,783,061...19,029,441 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:4867601|PMID:20935145) MGI PMID:20935145 MGI:MGI:4867601 NCBI chrNW_004955467:9,241,391...9,256,716 JBrowse link
G Vegfa vascular endothelial growth factor A ISO (PMID:19652095) BHF-UCL PMID:19652095 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 ISO PMID:23392669
(PMID:21113145)
ParkinsonsUK-UCL PMID:21113145, PMID:23392669 RGD:10047168 NCBI chrNW_004955413:25,406,589...25,408,727 JBrowse link
G Chd6 chromodomain helicase DNA binding protein 6 ISO (PMID:16314513) UniProtKB PMID:16314513 NCBI chrNW_004955445:15,360,074...15,576,410 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO PMID:16314513 UniProt PMID:16314513 RGD:8655528 NCBI chrNW_004955403:19,510,122...19,536,428 JBrowse link
G Sesn2 sestrin 2 ISO (PMID:23274085) UniProtKB PMID:23274085 NCBI chrNW_004955452:7,392,644...7,417,204 JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcn1 GCN1 activator of EIF2AK4 ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chrNW_004955455:11,416,222...11,474,791 JBrowse link
G Mapk7 mitogen-activated protein kinase 7 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chrNW_004955467:381,801...387,078 JBrowse link
G Muc1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
G Nfe2l1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:4820675|PMID:20385086), (MGI:MGI:6107583|PMID:11342101), (MGI:MGI:6316451|PMID:10601325) UniProt PMID:10601325, PMID:11342101, PMID:20385086 MGI:MGI:4820675, MGI:MGI:6107583, MGI:MGI:6316451 NCBI chrNW_004955451:13,088,680...13,099,839 JBrowse link
G Nfe2l2 nuclear factor, erythroid 2 like 2 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chrNW_004955403:19,510,122...19,536,428 JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5883206|PMID:22262176)
(PMID:30089260)
CAFA
ARUK-UCL
PMID:22262176, PMID:30089260 MGI:MGI:5883206 NCBI chrNW_004955467:9,241,391...9,256,716 JBrowse link
regulation of transcription from RNA polymerase II promoter in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 ISO (PMID:30089260) ARUK-UCL PMID:30089260 NCBI chrNW_004955467:9,241,391...9,256,716 JBrowse link
regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bach1 BTB domain and CNC homolog 1 ISO (PMID:12511571) UniProtKB PMID:12511571 NCBI chrNW_004955407:28,678,181...28,701,115 JBrowse link
G Egr1 early growth response 1 ISO (MGI:MGI:3847400|PMID:18323529) MGI PMID:18323529 MGI:MGI:3847400 NCBI chrNW_004955418:2,001,509...2,005,269 JBrowse link
G Stox1 storkhead box 1 ISO (PMID:24738702) UniProtKB PMID:24738702 NCBI chrNW_004955437:22,122,296...22,165,848 JBrowse link
regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 ISO (PMID:24434510) MGI PMID:24434510 NCBI chrNW_004955507:3,678,009...3,686,967 JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator ISO (PMID:8089148) BHF-UCL PMID:8089148 NCBI chrNW_004955588:159,462...233,047 JBrowse link
G Epas1 endothelial PAS domain protein 1 NOT ISO (MGI:MGI:2681387|PMID:14608355)
(MGI:MGI:2667513|PMID:12832481)
(MGI:MGI:3703197|PMID:17284606)
MGI PMID:12832481, PMID:14608355, PMID:17284606 MGI:MGI:2667513, MGI:MGI:2681387, MGI:MGI:3703197 NCBI chrNW_004955441:13,244,626...13,328,220 JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO (MGI:MGI:2667513|PMID:12832481)
(PMID:8089148), (PMID:8387214)
RGD
MGI
BHF-UCL
PMID:8089148, PMID:8387214, PMID:12832481, PMID:18614764 MGI:MGI:2667513, RGD:2301848 NCBI chrNW_004955466:8,000,311...8,022,497 JBrowse link
G Hmox1 heme oxygenase 1 ISO PMID:17430897 BHF-UCL PMID:17430897 RGD:8553479 NCBI chrNW_004955405:43,124,447...43,128,873 JBrowse link
G Sin3a SIN3 transcription regulator family member A ISO RGD PMID:18945670 RGD:2306468 NCBI chrNW_004955450:2,804,551...2,870,450 JBrowse link
regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chrNW_004955545:1,657,728...1,662,112 JBrowse link
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 ISO (MGI:MGI:5294291|PMID:18243098) UniProtKB PMID:18243098 MGI:MGI:5294291 NCBI chrNW_004955412:26,627,606...26,650,554 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11860
    cellular process 11055
      cellular response to stimulus 5090
        cellular response to stress 1646
          regulation of DNA-templated transcription in response to stress 49
            regulation of transcription from RNA polymerase II promoter in response to stress + 45
Path 2
Term Annotations click to browse term
  biological_process 11860
    metabolic process 7594
      cellular metabolic process 7006
        cellular aromatic compound metabolic process 3726
          nucleobase-containing compound metabolic process 3555
            nucleic acid metabolic process 3268
              RNA metabolic process 2898
                RNA biosynthetic process 2350
                  nucleic acid-templated transcription 2343
                    transcription, DNA-templated 2335
                      regulation of transcription, DNA-templated 2259
                        regulation of DNA-templated transcription in response to stress 49
                          regulation of transcription from RNA polymerase II promoter in response to stress + 45
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.