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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated transcription in response to stress
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Accession:GO:0043620 term browser browse the term
Definition:Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Synonyms:exact_synonym: regulation of DNA-dependent transcription in response to stress


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regulation of DNA-templated transcription in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCLAF1 BCL2 associated transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:28,852,654...28,882,095
Ensembl chr 1:28,855,041...28,882,006
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link
G RGS14 regulator of G protein signaling 14 IEA Ensembl GO_REF:0000107 NCBI chr 4:35,984,970...35,999,386
Ensembl chr 4:35,985,132...35,999,294
JBrowse link
G TCIM transcriptional and immune response regulator IEA Ensembl GO_REF:0000107 NCBI chr16:25,212,117...25,213,600
Ensembl chr16:25,213,023...25,213,343
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:21113145) ParkinsonsUK-UCL PMID:21113145 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G NCK1 NCK adaptor protein 1 IEA Ensembl GO_REF:0000107 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534
JBrowse link
G NCK2 NCK adaptor protein 2 IEA Ensembl GO_REF:0000107 NCBI chr10:37,584,351...37,734,388
Ensembl chr10:37,585,565...37,732,994
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO (MGI:MGI:5605960|PMID:11381086) ParkinsonsUK-UCL PMID:11381086 MGI:MGI:5605960 NCBI chr 1:107,486,399...107,490,151
Ensembl chr 1:107,486,438...107,489,222
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 IEA Ensembl GO_REF:0000107 NCBI chr27:4,921,606...4,944,830
Ensembl chr27:4,921,606...4,944,783
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (PMID:22735262) BHF-UCL PMID:22735262 NCBI chr 1:31,522,911...31,525,342
Ensembl chr 1:31,523,799...31,524,995
JBrowse link
G HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr28:13,253,646...13,277,997
Ensembl chr28:13,258,765...13,267,608
JBrowse link
G SIRT2 sirtuin 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:114,224,922...114,235,041
Ensembl chr 1:114,224,900...114,234,583
JBrowse link
G VHL von Hippel-Lindau tumor suppressor ISO (PMID:11641274) UniProtKB PMID:11641274 NCBI chr20:8,206,616...8,211,347
Ensembl chr20:8,206,616...8,211,323
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 IEA Ensembl GO_REF:0000107 NCBI chr28:29,792,612...29,815,466
Ensembl chr28:29,792,777...29,815,138
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 IEA Ensembl GO_REF:0000107 NCBI chr20:48,120,604...48,131,091
Ensembl chr20:48,121,379...48,130,060
JBrowse link
G HSP70 heat shock protein 70 ISO (PMID:9499401) UniProtKB PMID:9499401 NCBI chr12:1,285,282...1,287,670 JBrowse link
G IMPACT impact RWD domain protein IEA Ensembl GO_REF:0000107 NCBI chr 7:63,947,117...63,976,628
Ensembl chr 7:63,948,157...63,976,613
JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:6101031|PMID:29149604) UniProt PMID:29149604 MGI:MGI:6101031 NCBI chr 9:24,344,697...24,356,918
Ensembl chr 9:24,346,585...24,362,646
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEDD4 NEDD4 E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr30:21,123,333...21,229,907
Ensembl chr30:21,126,043...21,229,870
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 7:10,784,445...10,795,285
Ensembl chr 7:10,782,064...10,794,163
JBrowse link
G ATF4 activating transcription factor 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G ATF6 activating transcription factor 6 IEA Ensembl GO_REF:0000107 NCBI chr38:20,705,167...20,903,852
Ensembl chr38:20,709,038...20,903,814
JBrowse link
G ATF6B activating transcription factor 6 beta IEA Ensembl GO_REF:0000107 NCBI chr12:1,515,186...1,525,165
Ensembl chr12:1,515,503...1,525,110
JBrowse link
G CEBPB CCAAT enhancer binding protein beta IEA Ensembl GO_REF:0000107 NCBI chr24:36,661,294...36,663,162
Ensembl chr24:36,661,616...36,662,656
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 ISO (MGI:MGI:5616321|PMID:15665855) ParkinsonsUK-UCL PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chr18:43,138,779...43,173,535
Ensembl chr18:43,139,453...43,173,420
JBrowse link
G CREB3L3 cAMP responsive element binding protein 3 like 3 IEA Ensembl GO_REF:0000107 NCBI chr20:55,426,406...55,439,070
Ensembl chr20:55,426,813...55,436,882
JBrowse link
G DDIT3 DNA damage inducible transcript 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:1,606,693...1,612,410
Ensembl chr10:1,606,693...1,611,303
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr  X:17,655,295...17,718,960
Ensembl chr  X:17,655,363...17,710,288
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
G NOTCH1 notch receptor 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:48,975,972...49,018,985
Ensembl chr 9:48,974,757...49,017,277
JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region IEA Ensembl GO_REF:0000107 NCBI chr 3:84,060,417...84,286,008
Ensembl chr 3:84,064,440...84,286,360
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
G VEGFA vascular endothelial growth factor A ISO (PMID:19652095) BHF-UCL PMID:19652095 NCBI chr12:12,209,032...12,224,978
Ensembl chr12:12,208,231...12,224,965
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993
JBrowse link
G CHD6 chromodomain helicase DNA binding protein 6 IEA Ensembl GO_REF:0000107 NCBI chr24:29,397,320...29,601,206
Ensembl chr24:29,397,306...29,601,350
JBrowse link
G MT3 metallothionein 3 IEA Ensembl GO_REF:0000107 Ensembl chr 2:59,624,849...59,626,424 JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO PMID:16314513 UniProt PMID:16314513 RGD:8655528 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
G SESN2 sestrin 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCN1 GCN1 activator of EIF2AK4 IEA Ensembl GO_REF:0000107 NCBI chr26:16,087,380...16,146,865
Ensembl chr26:16,087,382...16,146,813
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 IEA Ensembl GO_REF:0000107 NCBI chr 5:40,831,949...40,836,990
Ensembl chr 5:40,831,947...40,836,505
JBrowse link
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:4820675|PMID:20385086), (MGI:MGI:6107583|PMID:11342101), (MGI:MGI:6316451|PMID:10601325) UniProt PMID:10601325, PMID:11342101, PMID:20385086 MGI:MGI:4820675, MGI:MGI:6107583, MGI:MGI:6316451 NCBI chr 9:24,344,697...24,356,918
Ensembl chr 9:24,346,585...24,362,646
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524
JBrowse link
G TP53 tumor protein p53 ISO (PMID:30089260)
(MGI:MGI:5883206|PMID:22262176)
ARUK-UCL
CAFA
PMID:22262176, PMID:30089260 MGI:MGI:5883206 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BACH1 BTB domain and CNC homolog 1 IEA Ensembl GO_REF:0000107 NCBI chr31:24,269,310...24,310,369
Ensembl chr31:24,269,280...24,381,454
JBrowse link
G EGR1 early growth response 1 IEA Ensembl GO_REF:0000107 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575
JBrowse link
G STOX1 storkhead box 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:20,013,893...20,065,480
Ensembl chr 4:20,014,007...20,060,394
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 IEA Ensembl GO_REF:0000107 NCBI chr28:10,838,677...10,848,406
Ensembl chr28:10,834,411...10,848,406
JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator IEA Ensembl GO_REF:0000107 Ensembl chr17:59,941,353...60,010,867 JBrowse link
G EPAS1 endothelial PAS domain protein 1 NOT IEA
ISO
(MGI:MGI:2667513|PMID:12832481) Ensembl
MGI
PMID:12832481 GO_REF:0000107, MGI:MGI:2667513 NCBI chr10:48,550,836...48,636,776
Ensembl chr10:48,551,410...48,634,844
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692
JBrowse link
G HMOX1 heme oxygenase 1 ISO PMID:17430897 BHF-UCL PMID:17430897 RGD:8553479 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G SIN3A SIN3 transcription regulator family member A ISO RGD PMID:18945670 RGD:2306468 NCBI chr30:38,231,844...38,306,665
Ensembl chr30:38,232,680...38,382,635
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INO80 INO80 complex ATPase subunit IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr30:8,100,536...8,229,868
Ensembl chr30:8,101,934...8,202,025
JBrowse link
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 7:42,338,939...42,344,690
Ensembl chr 7:42,340,375...42,344,690
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:8,878,511...8,910,626
Ensembl chr 5:8,879,147...8,907,669
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    cellular process 15440
      cellular response to stimulus 7183
        cellular response to stress 1901
          regulation of DNA-templated transcription in response to stress 52
            regulation of transcription from RNA polymerase II promoter in response to stress + 48
Path 2
Term Annotations click to browse term
  biological_process 16162
    metabolic process 10639
      cellular metabolic process 9631
        cellular aromatic compound metabolic process 5109
          nucleobase-containing compound metabolic process 4907
            nucleic acid metabolic process 4459
              RNA metabolic process 4001
                RNA biosynthetic process 3147
                  nucleic acid-templated transcription 3136
                    transcription, DNA-templated 3089
                      regulation of transcription, DNA-templated 2976
                        regulation of DNA-templated transcription in response to stress 52
                          regulation of transcription from RNA polymerase II promoter in response to stress + 48
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.