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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated transcription in response to stress
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Accession:GO:0043620 term browser browse the term
Definition:Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Synonyms:exact_synonym: regulation of DNA-dependent transcription in response to stress


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regulation of DNA-templated transcription in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCLAF1 BCL2 associated transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:27,872,167...27,902,980
Ensembl chr 1:27,872,184...27,919,899
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit IEA Ensembl GO_REF:0000107 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,471
JBrowse link
G RGS14 regulator of G protein signaling 14 IEA Ensembl GO_REF:0000107 NCBI chr 2:80,574,411...80,589,998
Ensembl chr 2:80,574,411...80,590,003
JBrowse link
G TCIM transcriptional and immune response regulator IEA Ensembl GO_REF:0000107 NCBI chr17:9,441,488...9,443,053
Ensembl chr17:9,441,766...9,442,086
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO (PMID:21113145) ParkinsonsUK-UCL PMID:21113145 NCBI chr 6:153,686,425...153,687,635 JBrowse link
G NCK1 NCK adaptor protein 1 IEA Ensembl GO_REF:0000107 NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,986,156
JBrowse link
G NCK2 NCK adaptor protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,988...49,198,664
JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO (MGI:MGI:5605960|PMID:11381086) ParkinsonsUK-UCL PMID:11381086 MGI:MGI:5605960 NCBI chr 6:54,172,038...54,175,461
Ensembl chr 6:54,172,050...54,175,465
JBrowse link
G TMBIM6 transmembrane BAX inhibitor motif containing 6 IEA Ensembl GO_REF:0000107 NCBI chr 5:15,674,028...15,692,944
Ensembl chr 5:15,674,049...15,723,328
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CITED2 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 ISO (PMID:22735262) BHF-UCL PMID:22735262 NCBI chr 1:25,155,652...25,158,517
Ensembl chr 1:25,155,664...25,160,279
JBrowse link
G HIF1AN hypoxia inducible factor 1 subunit alpha inhibitor IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr14:111,636,317...111,654,659
Ensembl chr14:111,636,376...111,652,527
JBrowse link
G SIRT2 sirtuin 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:47,682,427...47,703,408
Ensembl chr 6:47,682,424...47,703,529
JBrowse link
G VHL von Hippel-Lindau tumor suppressor IEA Ensembl GO_REF:0000107 NCBI chr13:66,334,535...66,342,401
Ensembl chr13:66,334,591...66,342,654
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG3 BAG cochaperone 3 IEA Ensembl GO_REF:0000107 NCBI chr14:129,510,240...129,533,998
Ensembl chr14:129,510,293...129,533,996
JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 IEA Ensembl GO_REF:0000107 NCBI chr 2:64,761,672...64,764,482
Ensembl chr 2:64,750,820...64,765,485
JBrowse link
G IMPACT impact RWD domain protein ISO (MGI:MGI:5576818|PMID:24333428) UniProtKB PMID:24333428 MGI:MGI:5576818 NCBI chr 6:109,235,590...109,272,801
Ensembl chr 6:109,235,585...109,319,482
JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:6101031|PMID:29149604) UniProt PMID:29149604 MGI:MGI:6101031 NCBI chr12:24,303,381...24,316,765
Ensembl chr12:24,303,399...24,316,763
JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEDD4 NEDD4 E3 ubiquitin protein ligase IEA Ensembl GO_REF:0000107 NCBI chr 1:115,941,945...116,069,884
Ensembl chr 1:115,941,937...116,070,317
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 IEA Ensembl GO_REF:0000107 NCBI chr 9:130,772,259...130,829,678
Ensembl chr 9:130,770,428...130,787,462
JBrowse link
G ATF4 activating transcription factor 4 IEA Ensembl GO_REF:0000107 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,738,880...8,745,225
JBrowse link
G ATF6 activating transcription factor 6 IEA Ensembl GO_REF:0000107 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,280...88,818,372
JBrowse link
G ATF6B activating transcription factor 6 beta IEA Ensembl GO_REF:0000107 NCBI chr 7:24,153,551...24,171,743
Ensembl chr 7:24,153,572...24,171,840
JBrowse link
G CEBPB CCAAT enhancer binding protein beta IEA Ensembl GO_REF:0000107 NCBI chr17:51,722,633...51,723,673
Ensembl chr17:51,722,426...51,724,305
JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 ISO PMID:15665855
(MGI:MGI:5616321|PMID:15665855)
ParkinsonsUK-UCL PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chr 2:16,186,206...16,220,948
Ensembl chr 2:16,186,210...16,220,937
JBrowse link
G CREB3L3 cAMP responsive element binding protein 3 like 3 IEA Ensembl GO_REF:0000107 NCBI chr 2:74,578,471...74,588,269
Ensembl chr 2:74,578,486...74,601,784
JBrowse link
G DDIT3 DNA damage inducible transcript 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,441...22,791,134
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,875...57,506,247
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:18,013,360...18,054,250 JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSF1 heat shock transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 4:463,531...486,483
Ensembl chr 4:461,559...486,473
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 IEA Ensembl GO_REF:0000107 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G NOTCH1 notch receptor 1 IEA Ensembl GO_REF:0000107
G RBPJ recombination signal binding protein for immunoglobulin kappa J region IEA Ensembl GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,755
JBrowse link
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
G VEGFA vascular endothelial growth factor A ISO (PMID:19652095) BHF-UCL PMID:19652095 NCBI chr 7:38,746,393...38,762,282
Ensembl chr 7:38,746,052...38,761,038
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO (PMID:21113145)
PMID:23392669
ParkinsonsUK-UCL PMID:21113145, PMID:23392669 RGD:10047168 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,738,880...8,745,225
JBrowse link
G CHD6 chromodomain helicase DNA binding protein 6 IEA Ensembl GO_REF:0000107 NCBI chr17:44,048,056...44,265,472
Ensembl chr17:44,047,803...44,265,431
JBrowse link
G MT3 metallothionein 3 ISS
IEA
UniProt
Ensembl
GO_REF:0000024, GO_REF:0000107 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,721...18,789,137
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO PMID:16314513 UniProt PMID:16314513 RGD:8655528 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G SESN2 sestrin 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:85,321,982...85,348,044
Ensembl chr 6:85,324,228...85,348,044
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GCN1 GCN1 activator of EIF2AK4 IEA Ensembl GO_REF:0000107 NCBI chr14:40,151,415...40,218,183
Ensembl chr14:40,146,345...40,218,097
JBrowse link
G KLF2 Kruppel like factor 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:61,270,733...61,273,037
Ensembl chr 2:61,270,714...61,273,139
JBrowse link
G MAPK7 mitogen-activated protein kinase 7 IEA Ensembl GO_REF:0000107 NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,128,686...60,149,270
JBrowse link
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 4:94,626,317...94,631,194 JBrowse link
G NFE2L1 nuclear factor, erythroid 2 like 1 ISO (MGI:MGI:4820675|PMID:20385086), (MGI:MGI:6107583|PMID:11342101), (MGI:MGI:6316451|PMID:10601325) UniProt PMID:10601325, PMID:11342101, PMID:20385086 MGI:MGI:4820675, MGI:MGI:6107583, MGI:MGI:6316451 NCBI chr12:24,303,381...24,316,765
Ensembl chr12:24,303,399...24,316,763
JBrowse link
G NFE2L2 nuclear factor, erythroid 2 like 2 ISO (PMID:23043106) BHF-UCL PMID:23043106 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,648...83,146,183
JBrowse link
G TP53 tumor protein p53 ISO (MGI:MGI:5883206|PMID:22262176)
(PMID:30089260)
CAFA
ARUK-UCL
PMID:22262176, PMID:30089260 MGI:MGI:5883206 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BACH1 BTB domain and CNC homolog 1 IEA Ensembl GO_REF:0000107 NCBI chr13:192,656,289...192,697,536
Ensembl chr13:192,656,322...192,697,537
JBrowse link
G EGR1 early growth response 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296
JBrowse link
G STOX1 storkhead box 1 IEA Ensembl GO_REF:0000107 NCBI chr14:71,927,387...71,985,239
Ensembl chr14:71,928,399...71,985,233
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKRD2 ankyrin repeat domain 2 IEA Ensembl GO_REF:0000107 Ensembl chr14:108,944,534...108,959,382 JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator IEA Ensembl GO_REF:0000107 NCBI chr 4:98,333,431...98,390,012
Ensembl chr 4:98,333,459...98,404,961
JBrowse link
G EPAS1 endothelial PAS domain protein 1 NOT IEA
ISO
(MGI:MGI:2667513|PMID:12832481) Ensembl
MGI
PMID:12832481 GO_REF:0000107, MGI:MGI:2667513 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,815...94,254,079
JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEA Ensembl GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,181...190,674,850
JBrowse link
G HMOX1 heme oxygenase 1 ISO PMID:17430897 BHF-UCL PMID:17430897 RGD:8553479
G SIN3A SIN3 transcription regulator family member A ISO RGD PMID:18945670 RGD:2306468 NCBI chr 7:58,171,821...58,246,126
Ensembl chr 7:58,176,166...58,245,762
JBrowse link
regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INO80 INO80 complex ATPase subunit IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:130,201,705...130,341,627
Ensembl chr 1:130,201,718...130,342,840
JBrowse link
G MUC1 mucin 1, cell surface associated ISO (PMID:15710329) BHF-UCL PMID:15710329 NCBI chr 4:94,626,317...94,631,194 JBrowse link
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHEK1 checkpoint kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:52,759,224...52,790,878
Ensembl chr 9:52,726,885...52,790,706
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16525
    cellular process 15757
      cellular response to stimulus 7610
        cellular response to stress 1896
          regulation of DNA-templated transcription in response to stress 52
            regulation of transcription from RNA polymerase II promoter in response to stress + 48
Path 2
Term Annotations click to browse term
  biological_process 16525
    metabolic process 10566
      cellular metabolic process 9561
        cellular aromatic compound metabolic process 5101
          nucleobase-containing compound metabolic process 4902
            nucleic acid metabolic process 4482
              RNA metabolic process 4015
                RNA biosynthetic process 3171
                  nucleic acid-templated transcription 3158
                    transcription, DNA-templated 3113
                      regulation of transcription, DNA-templated 3009
                        regulation of DNA-templated transcription in response to stress 52
                          regulation of transcription from RNA polymerase II promoter in response to stress + 48
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.