Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:DNA-N1-methyladenine dioxygenase activity
go back to main search page
Accession:GO:0043734 term browser browse the term
Definition:Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde.
Synonyms:narrow_synonym: alkB;   alpha-ketoglutarate-dependent dioxygenase
 xref: reactome:R-HSA-112118 "Oxidative demethylation of 1-meA damaged DNA by ALKBH2";   reactome:R-HSA-112123 "Oxidative demethylation of 1-meA damaged DNA By ALKBH3"


show annotations for term's descendants       view all columns           Sort by:
 
DNA-N1-methyladenine dioxygenase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase JBrowse link 12 48,257,575 48,262,244 RGD:1624291
RGD:13792537
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase JBrowse link 3 82,874,242 82,907,467 RGD:1600115
RGD:1624291
G Fto FTO, alpha-ketoglutarate dependent dioxygenase JBrowse link 19 16,774,549 17,115,098 RGD:1600115
RGD:13792537
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 19678
    catalytic activity 6023
      oxidoreductase activity 848
        dioxygenase activity 79
          2-oxoglutarate-dependent dioxygenase activity 49
            DNA-N1-methyladenine dioxygenase activity 3
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.