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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cAMP-mediated signaling
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Accession:GO:0043949 term browser browse the term
Definition:Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
Synonyms:exact_synonym: regulation of cAMP-mediated signalling


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regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gnai1 G protein subunit alpha i1 JBrowse link 4 13,405,136 13,486,866 RGD:10449520
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:1624291
G Pde4a phosphodiesterase 4A JBrowse link 8 22,189,533 22,234,036 RGD:1624291
RGD:1600115
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:2312596
G Pex5l peroxisomal biogenesis factor 5-like JBrowse link 2 119,330,330 119,405,809 RGD:8553454
G Rasd2 RASD family, member 2 JBrowse link 19 14,653,198 14,663,914 RGD:1304287
G Tcp11 t-complex 11 JBrowse link 20 7,645,619 7,657,222 RGD:1624291
RGD:1600115
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrdc3 arrestin domain containing 3 JBrowse link 2 8,732,907 8,745,445 RGD:1624291
RGD:1600115
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1600115
RGD:1624291
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13508593
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:1624291
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplp1 amyloid beta precursor like protein 1 JBrowse link 1 88,897,525 88,908,750 RGD:1624291
RGD:1600115
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13792694
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:13792694
G Mrap melanocortin 2 receptor accessory protein JBrowse link 11 30,904,733 30,915,225 RGD:1624291
G Mrap2 melanocortin 2 receptor accessory protein 2 JBrowse link 8 94,801,336 94,858,192 RGD:1624291
RGD:1600115
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835006
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:9835006
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:9850263
G Sstr4 somatostatin receptor 4 JBrowse link 3 142,739,781 142,741,644 RGD:2325010
negative regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplnr apelin receptor JBrowse link 3 72,540,538 72,544,183 RGD:12907555
RGD:13792537
RGD:1600115
RGD:1624291
G Cdc34 cell division cycle 34 JBrowse link 7 12,899,957 12,905,339 RGD:1624291
RGD:1600115
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:1624291
G Crtc3 CREB regulated transcription coactivator 3 JBrowse link 1 142,398,248 142,500,562 RGD:1624291
RGD:1600115
G LOC103694902 ubiquitin-conjugating enzyme E2 B RGD:1600115
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:727395
G Mgrn1 mahogunin ring finger 1 JBrowse link 10 10,832,573 10,881,999 RGD:1600115
RGD:13792537
RGD:1624291
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:633494
G Nucb2 nucleobindin 2 JBrowse link 1 185,106,773 185,143,278 RGD:9831186
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835005
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
RGD:1600115
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:68285
G Pde11a phosphodiesterase 11A JBrowse link 3 62,818,502 63,211,843 RGD:633590
RGD:13792537
G Pde11a_v1 phosphodiesterase 11A, variant 1 RGD:633590
G Pde11a_v2 phosphodiesterase 11A, variant 2 RGD:633590
G Pde11a_v3 phosphodiesterase 11A, variant 3 RGD:633590
RGD:13792537
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:625635
RGD:13792537
RGD:1624291
RGD:1600115
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:2312525
RGD:13792537
RGD:1624291
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:2312525
RGD:13792537
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1600115
RGD:13792537
RGD:1624291
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:1624291
RGD:1600115
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
RGD:1600115
positive regulation by host of symbiont cAMP-mediated signal transduction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Calm1 calmodulin 1 JBrowse link 6 124,217,241 124,225,292 RGD:1600115
RGD:1624291
G Calm2 calmodulin 2 JBrowse link 6 11,067,675 11,080,078 RGD:1600115
RGD:1624291
G Calm3 calmodulin 3 JBrowse link 1 78,844,520 78,851,628 RGD:1600115
RGD:1624291
positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1600115
RGD:1624291
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129138
G Gsk3a glycogen synthase kinase 3 alpha JBrowse link 1 82,097,244 82,108,238 RGD:1600115
RGD:1624291
G Mrap melanocortin 2 receptor accessory protein JBrowse link 11 30,904,733 30,915,225 RGD:1624291
G Mrap2 melanocortin 2 receptor accessory protein 2 JBrowse link 8 94,801,336 94,858,192 RGD:1624291
RGD:1600115
positive regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adcyap1 adenylate cyclase activating polypeptide 1 JBrowse link 9 121,705,897 121,725,736 RGD:2325275
G Adcyap1r1 ADCYAP receptor type I JBrowse link 4 85,662,809 85,711,696 RGD:2315974
G Adora2b adenosine A2B receptor JBrowse link 10 48,569,563 48,586,366 RGD:2316150
RGD:631750
G Cgas cyclic GMP-AMP synthase JBrowse link 8 85,789,515 85,804,008 RGD:1624291
G Chga chromogranin A JBrowse link 6 126,434,226 126,445,569 RGD:6906968
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:70047
G Crhr1 corticotropin releasing hormone receptor 1 JBrowse link 10 92,191,473 92,233,662 RGD:5491010
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5131269
RGD:1624291
RGD:5491010
RGD:5491003
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:7243859
G Ghrh growth hormone releasing hormone JBrowse link 3 153,449,124 153,468,794 RGD:1624957
G Gip gastric inhibitory polypeptide JBrowse link 10 83,835,080 83,848,399 RGD:2312537
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:2312607
G Gnas GNAS complex locus JBrowse link 3 172,374,957 172,434,988 RGD:1624291
RGD:1600115
G Gpr3 G protein-coupled receptor 3 JBrowse link 5 151,394,118 151,397,634 RGD:632931
G Gpr61 G protein-coupled receptor 61 JBrowse link 2 210,937,289 210,943,727 RGD:1600115
RGD:1624291
G Gpr62 G protein-coupled receptor 62 JBrowse link 8 115,165,655 115,170,396 RGD:1600115
RGD:1624291
G Insl3 insulin-like 3 JBrowse link 16 20,120,753 20,122,702 RGD:633070
G Olr59 olfactory receptor 59 JBrowse link 1 167,906,030 167,940,688 RGD:1600115
RGD:1624291
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
G Pebp1 phosphatidylethanolamine binding protein 1 JBrowse link 12 45,026,948 45,031,148 RGD:2302817
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10003101
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10003101
G Rapgef2 Rap guanine nucleotide exchange factor 2 JBrowse link 2 177,836,191 178,057,378 RGD:1600115
RGD:1624291
G Rxfp2 relaxin family peptide receptor 2 JBrowse link 12 6,016,884 6,078,411 RGD:1600172
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:9590237
G Sctr secretin receptor JBrowse link 13 36,039,241 36,090,515 RGD:9590237
RGD:1624291
G Taar1 trace-amine-associated receptor 1 JBrowse link 1 22,595,477 22,596,475 RGD:11531774
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:70047

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18007
    signaling 7058
      signal transduction 6548
        intracellular signal transduction 2549
          regulation of intracellular signal transduction 1649
            regulation of cAMP-mediated signaling 69
              modulation by host of symbiont cAMP-mediated signal transduction + 3
              modulation by symbiont of host cAMP-mediated signal transduction + 0
              negative regulation of cAMP-mediated signaling + 33
              positive regulation of cAMP-mediated signaling + 36
              regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 16
              regulation of cAMP-mediated signaling in response to host + 0
Path 2
Term Annotations click to browse term
  biological_process 18007
    biological regulation 12698
      regulation of biological process 12030
        regulation of cellular process 11367
          signal transduction 6548
            intracellular signal transduction 2549
              second-messenger-mediated signaling 465
                cyclic-nucleotide-mediated signaling 231
                  cAMP-mediated signaling 199
                    regulation of cAMP-mediated signaling 69
                      modulation by host of symbiont cAMP-mediated signal transduction + 3
                      modulation by symbiont of host cAMP-mediated signal transduction + 0
                      negative regulation of cAMP-mediated signaling + 33
                      positive regulation of cAMP-mediated signaling + 36
                      regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 16
                      regulation of cAMP-mediated signaling in response to host + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.