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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cAMP-mediated signaling
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Accession:GO:0043951 term browser browse the term
Definition:Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
Synonyms:exact_synonym: negative regulation of cAMP-mediated signalling


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negative regulation of cAMP-mediated signaling term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplnr apelin receptor JBrowse link 3 72,540,538 72,544,183 RGD:12907555
RGD:13792537
RGD:1600115
RGD:1624291
G Cdc34 cell division cycle 34, ubiqiutin conjugating enzyme JBrowse link 7 12,899,957 12,905,339 RGD:1624291
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:1624291
G Crtc3 CREB regulated transcription coactivator 3 JBrowse link 1 142,398,248 142,500,562 RGD:1624291
G Lpar1 lysophosphatidic acid receptor 1 JBrowse link 5 75,557,038 75,678,067 RGD:727395
G Mgrn1 mahogunin ring finger 1 JBrowse link 10 10,832,573 10,881,999 RGD:1600115
RGD:13792537
RGD:1624291
G Npy2r neuropeptide Y receptor Y2 JBrowse link 2 181,528,949 181,538,145 RGD:633494
G Nucb2 nucleobindin 2 JBrowse link 1 185,106,773 185,143,278 RGD:9831186
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835005
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:1624291
RGD:1600115
G Pde10a phosphodiesterase 10A JBrowse link 1 52,360,296 52,544,448 RGD:68285
G Pde11a phosphodiesterase 11A JBrowse link 3 62,818,502 63,211,843 RGD:633590
RGD:13792537
G Pde11a_v1 phosphodiesterase 11A, variant 1 RGD:633590
G Pde11a_v2 phosphodiesterase 11A, variant 2 RGD:633590
G Pde11a_v3 phosphodiesterase 11A, variant 3 RGD:633590
RGD:13792537
G Pde2a phosphodiesterase 2A JBrowse link 1 166,534,643 166,626,158 RGD:625635
RGD:13792537
RGD:1624291
RGD:1600115
G Pde3a phosphodiesterase 3A JBrowse link 4 175,431,904 175,703,844 RGD:2312525
RGD:13792537
RGD:1624291
G Pde3b phosphodiesterase 3B JBrowse link 1 183,892,841 184,078,071 RGD:2312525
RGD:13792537
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1600115
RGD:13792537
RGD:1624291
G Rgs2 regulator of G-protein signaling 2 JBrowse link 13 60,846,458 60,849,061 RGD:1624291
G Rnf157 ring finger protein 157 JBrowse link 10 105,291,148 105,368,316 RGD:13792537
G Ube2b ubiquitin-conjugating enzyme E2B JBrowse link 10 37,439,947 37,454,867 RGD:1624291
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arrdc3 arrestin domain containing 3 JBrowse link 2 8,732,907 8,745,445 RGD:1624291
negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 JBrowse link 13 50,091,644 50,153,808 RGD:1624291
G Gnai2 G protein subunit alpha i2 JBrowse link 8 116,370,730 116,391,337 RGD:13508593
G Pde4b phosphodiesterase 4B JBrowse link 5 121,759,236 122,136,814 RGD:1624291
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplp1 amyloid beta precursor like protein 1 JBrowse link 1 88,897,525 88,908,750 RGD:1624291
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:13792694
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:13792694
G Mrap melanocortin 2 receptor accessory protein JBrowse link 11 30,904,733 30,915,225 RGD:1624291
G Mrap2 melanocortin 2 receptor accessory protein 2 JBrowse link 8 94,801,336 94,858,192 RGD:1624291
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835006
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:9835006
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:9850263
G Sstr4 somatostatin receptor 4 JBrowse link 3 142,739,781 142,741,644 RGD:2325010

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    signaling 7553
      negative regulation of signaling 1396
        negative regulation of signal transduction 1232
          negative regulation of intracellular signal transduction 546
            negative regulation of cAMP-mediated signaling 33
              negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 13
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        regulation of cellular process 12442
          signal transduction 6968
            intracellular signal transduction 2597
              second-messenger-mediated signaling 481
                cyclic-nucleotide-mediated signaling 236
                  cAMP-mediated signaling 207
                    regulation of cAMP-mediated signaling 71
                      negative regulation of cAMP-mediated signaling 33
                        negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway + 13
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.