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ONTOLOGY REPORT - ANNOTATIONS


Term:endoplasmic reticulum quality control compartment
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Accession:GO:0044322 term browser browse the term
Definition:A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.
Synonyms:exact_synonym: ER quality control compartment;   ERQC
 related_synonym: ER-derived quality control compartment


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endoplasmic reticulum quality control compartment term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asgr2 asialoglycoprotein receptor 2 JBrowse link 10 56,710,446 56,723,608 RGD:1624291
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:1624291
G Canx calnexin JBrowse link 10 35,800,942 35,833,939 RGD:1624291
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1600115
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1600115
G Fbxo6 F-box protein 6 JBrowse link 5 164,956,285 164,962,075 RGD:1624291
RGD:13792537
G Man1b1 mannosidase, alpha, class 1B, member 1 JBrowse link 3 2,547,259 2,569,051 RGD:1624291
G Rhbdd1 rhomboid domain containing 1 JBrowse link 9 88,110,731 88,229,462 RGD:1624291
RGD:1600115
G Sec61b SEC61 translocon subunit beta JBrowse link 5 63,192,322 63,200,532 RGD:1624291

Term paths to the root
Path 1
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  cellular_component 19949
    cellular anatomical entity 19598
      endoplasmic reticulum quality control compartment 9
Path 2
Term Annotations click to browse term
  cellular_component 19949
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          intracellular membrane-bounded organelle 10066
            endoplasmic reticulum 1302
              endoplasmic reticulum quality control compartment 9
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.