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ONTOLOGY REPORT - ANNOTATIONS


Term:long-chain fatty acid import into cell
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Accession:GO:0044539 term browser browse the term
Definition:The directed movement of a long-chain fatty acid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
Synonyms:exact_synonym: long-chain fatty acid uptake
 related_synonym: long-chain fatty acid import


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long-chain fatty acid import into cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 ISO
IMP
(PMID:22022213)
PMID:23024797
RGD PMID:22022213, PMID:23024797 RGD:39458021 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 ISO (PMID:20219900) RGD PMID:20219900 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Cd36 CD36 molecule ISO
ISS
(MGI:MGI:3718873|PMID:17507371)
(PMID:17416590), (PMID:22022213)
GO_REF:0000024
RGD
UniProt
PMID:17416590, PMID:17507371, PMID:22022213 GO_REF:0000024, MGI:MGI:3718873 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 ISS
ISO
GO_REF:0000024
(MGI:MGI:5913528|PMID:28178239)
UniProt
RGD
PMID:28178239 GO_REF:0000024, MGI:MGI:5913528 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Slc27a1 solute carrier family 27 member 1 ISO
IBA
ISS
(PMID:28178239)
(MGI:MGI:6154651|PMID:12235169), (MGI:MGI:69386|PMID:7954810), (PMID:23024797)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:7954810, PMID:12235169, PMID:23024797, PMID:28178239, PMID:21873635 GO_REF:0000024, MGI:MGI:6154651, MGI:MGI:69386, RGD:13792537 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc27a2 solute carrier family 27 member 2 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:22022213)
Ensembl
RGD
PMID:22022213, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc27a4 solute carrier family 27 member 4 ISO
IBA
(PMID:22022213)
(MGI:MGI:5314874|PMID:21750264), (MGI:MGI:5703705|PMID:24503477), (PMID:23024797)
PMID:21873635
RGD PMID:21750264, PMID:22022213, PMID:23024797, PMID:24503477, PMID:21873635 MGI:MGI:5314874, MGI:MGI:5703705, RGD:13792537 NCBI chr 3:8,363,937...8,376,858
Ensembl chr 3:8,363,937...8,376,858
JBrowse link
G Spx spexin hormone IDA
ISO
PMID:24550067
(MGI:MGI:5574430|PMID:24550067)
RGD PMID:24550067, PMID:24550067 MGI:MGI:5574430, RGD:8693351 NCBI chr 4:176,629,597...176,635,698
Ensembl chr 4:176,629,800...176,641,008
JBrowse link
long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 IDA leukotriene LTC4 transport RGD PMID:12867490 RGD:2303048 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Cd36 CD36 molecule ISO (PMID:24503477) RGD PMID:24503477 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Slc27a1 solute carrier family 27 member 1 ISO
IEA
(PMID:28035674)
GO_REF:0000107
RGD
Ensembl
PMID:28035674 GO_REF:0000107 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc27a5 solute carrier family 27 member 5 ISO
IBA
MGI:MGI:3757682 (MGI:MGI:3722951|PMID:16618416)
PMID:21873635
RGD PMID:16618416, PMID:21873635 MGI:MGI:3722951, RGD:13792537 NCBI chr 1:65,576,599...65,587,192
Ensembl chr 1:65,576,535...65,587,186
JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO (PMID:10227690) RGD PMID:10227690 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:16814735) RGD PMID:16814735 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO
IEA
(PMID:16814735)
GO_REF:0000107
RGD
Ensembl
PMID:16814735 GO_REF:0000107 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Irs2 insulin receptor substrate 2 ISO (PMID:16814735) RGD PMID:16814735 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:17416590) RGD PMID:17416590 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
positive regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl1 acyl-CoA synthetase long-chain family member 1 IDA PMID:24503477 ARUK-UCL PMID:24503477 RGD:39458020 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:16263710, PMID:21873635 RGD:2312807, RGD:13792537 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 IMP RGD PMID:15655248 RGD:2312811 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
positive regulation of long-chain fatty acid import into cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp3 fatty acid binding protein 3 ISO (MGI:MGI:1336545|PMID:10224224), (MGI:MGI:3575839|PMID:15835924) RGD PMID:10224224, PMID:15835924 MGI:MGI:1336545, MGI:MGI:3575839 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
regulation of long-chain fatty acid import into cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eprs glutamyl-prolyl-tRNA synthetase ISO (PMID:28178239)
(MGI:MGI:5913528|PMID:28178239)
RGD PMID:28178239 MGI:MGI:5913528 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    localization 6478
      macromolecule localization 3039
        lipid localization 459
          lipid transport 407
            lipid import into cell 19
              long-chain fatty acid import into cell 19
                long-chain fatty acid import across plasma membrane + 12
                negative regulation of long-chain fatty acid import into cell + 4
                positive regulation of long-chain fatty acid import into cell + 4
                regulation of long-chain fatty acid import into cell + 9
Path 2
Term Annotations click to browse term
  biological_process 20028
    localization 6478
      establishment of localization 4887
        transport 4735
          ion transport 1786
            anion transport 679
              organic anion transport 535
                carboxylic acid transport 369
                  monocarboxylic acid transport 191
                    fatty acid transport 104
                      long-chain fatty acid transport 71
                        long-chain fatty acid import into cell 19
                          long-chain fatty acid import across plasma membrane + 12
                          negative regulation of long-chain fatty acid import into cell + 4
                          positive regulation of long-chain fatty acid import into cell + 4
                          regulation of long-chain fatty acid import into cell + 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.