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ONTOLOGY REPORT - ANNOTATIONS


Term:NLRP3 inflammasome complex assembly
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Accession:GO:0044546 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.
Synonyms:exact_synonym: NALP3 inflammasome complex assembly
 related_synonym: NLRP3 inflammasome activation


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NLRP3 inflammasome complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 ISO (PMID:19158676) RGD PMID:19158676 NCBI chr13:91,919,834...91,963,080
Ensembl chr13:91,954,138...91,962,588
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 ISO MGI:MGI:5465108 (MGI:MGI:5446983|PMID:22753929) RGD PMID:22753929 MGI:MGI:5446983 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cptp ceramide-1-phosphate transfer protein ISS
ISO
GO_REF:0000024
(PMID:29164996)
UniProt
RGD
PMID:29164996 GO_REF:0000024 NCBI chr 5:173,314,219...173,318,384
Ensembl chr 5:173,314,228...173,318,313
JBrowse link
G Mefv MEFV innate immuity regulator, pyrin ISO
ISS
(PMID:26347139)
GO_REF:0000024
RGD
UniProt
PMID:26347139 GO_REF:0000024 NCBI chr10:12,045,813...12,056,229
Ensembl chr10:12,046,541...12,056,311
JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,809,531...11,844,184
Ensembl chr10:11,810,926...11,842,482
JBrowse link
G Sirt2 sirtuin 2 ISO
IEA
(MGI:MGI:5488534|PMID:23502856)
GO_REF:0000107
RGD
Ensembl
PMID:23502856 GO_REF:0000107, MGI:MGI:5488534 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952
JBrowse link
positive regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 ISO (MGI:MGI:5488534|PMID:23502856) RGD PMID:23502856 MGI:MGI:5488534 NCBI chr20:3,351,269...3,364,565
Ensembl chr20:3,351,303...3,364,565
JBrowse link
G Cd36 CD36 molecule ISO
ISS
(MGI:MGI:5546292|PMID:23812099)
GO_REF:0000024
RGD
UniProt
PMID:23812099 GO_REF:0000024, MGI:MGI:5546292 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO (MGI:MGI:6368386|PMID:31511697) RGD PMID:31511697 MGI:MGI:6368386 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Dhx33 DEAH-box helicase 33 ISO (PMID:23871209) RGD PMID:23871209 NCBI chr10:57,622,022...57,638,485
Ensembl chr10:57,622,022...57,638,485
JBrowse link
G Gbp5 guanylate binding protein 5 ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:248,178,441...248,196,873
Ensembl chr 2:248,178,389...248,197,160
JBrowse link
G Stmp1 short transmembrane mitochondrial protein 1 ISO (MGI:MGI:6384515|PMID:31836654) RGD PMID:31836654 MGI:MGI:6384515 NCBI chr 4:62,780,596...62,790,428
Ensembl chr 4:62,780,596...62,790,422
JBrowse link
G Tlr4 toll-like receptor 4 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(MGI:MGI:5546292|PMID:23812099)
Ensembl
UniProt
RGD
PMID:23812099 GO_REF:0000024, GO_REF:0000107, MGI:MGI:5546292 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tlr6 toll-like receptor 6 ISO (MGI:MGI:5546292|PMID:23812099) RGD PMID:23812099 MGI:MGI:5546292 NCBI chr14:45,024,351...45,041,188
Ensembl chr14:45,024,351...45,046,446
JBrowse link
G Usp50 ubiquitin specific peptidase 50 ISO (MGI:MGI:5888801|PMID:28094437)
(PMID:28094437)
RGD PMID:28094437 MGI:MGI:5888801 NCBI chr 3:119,225,055...119,247,442
Ensembl chr 3:119,224,943...119,247,449
JBrowse link
regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 ISO
ISS
(MGI:MGI:5432942|PMID:22801494)
GO_REF:0000024
RGD
UniProt
PMID:22801494 GO_REF:0000024, MGI:MGI:5432942 NCBI chr 6:1,428,845...1,466,193
Ensembl chr 6:1,428,834...1,466,201
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          cellular component assembly 2967
            protein-containing complex assembly 1603
              cellular protein-containing complex assembly 1130
                NLRP3 inflammasome complex assembly 16
                  negative regulation of NLRP3 inflammasome complex assembly 4
                  positive regulation of NLRP3 inflammasome complex assembly 9
                  regulation of NLRP3 inflammasome complex assembly + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.