Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic DNA damage checkpoint
go back to main search page
Accession:GO:0044773 term browser browse the term
Definition:A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage.


show annotations for term's descendants       view all columns           Sort by:
 
mitotic DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:13792537
G Stk33 serine/threonine kinase 33 JBrowse link 1 173,872,744 174,051,768 RGD:13792537
G Zfp830 zinc finger protein 830 JBrowse link 10 70,118,250 70,119,714 RGD:1624291
RGD:13792537
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 7 36,395,665 36,408,588 RGD:1624291
RGD:13792537
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1624291
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Pidd1 p53-induced death domain protein 1 JBrowse link 1 214,418,751 214,423,959 RGD:1624291
G Pml PML nuclear body scaffold JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:1624291
G Rbm38 RNA binding motif protein 38 JBrowse link 3 171,037,891 171,050,500 RGD:1624291
G Rpl26 ribosomal protein L26 JBrowse link 10 55,492,417 55,495,547 RGD:1624291
G Sox4 SRY-box transcription factor 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
intra-S DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf2 activating transcription factor 2 JBrowse link 3 60,721,137 60,795,951 RGD:1624291
RGD:1600115
G Eme1 essential meiotic structure-specific endonuclease 1 JBrowse link 10 82,366,820 82,375,510 RGD:13792537
G Eme2 essential meiotic structure-specific endonuclease subunit 2 JBrowse link 10 14,253,552 14,257,017 RGD:13792537
G Fancd2 FA complementation group D2 JBrowse link 4 145,489,869 145,551,479 RGD:13792537
G Hus1 HUS1 checkpoint clamp component JBrowse link 14 89,194,086 89,208,825 RGD:13792537
G LOC103690165 checkpoint protein HUS1B JBrowse link 17 34,691,084 34,694,690 RGD:13792537
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1600115
RGD:13792537
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1624291
RGD:1600115
G Mus81 MUS81 structure-specific endonuclease subunit JBrowse link 1 220,862,474 220,867,973 RGD:13792537
G Nek11 NIMA-related kinase 11 JBrowse link 8 113,703,406 113,937,097 RGD:1624291
RGD:13792537
G Rad9a RAD9 checkpoint clamp component A JBrowse link 1 219,443,347 219,450,574 RGD:1624291
RGD:13792537
G Rad9b RAD9 checkpoint clamp component B JBrowse link 12 39,699,076 39,731,218 RGD:13792537
G Tipin timeless interacting protein JBrowse link 8 69,753,363 69,768,640 RGD:1624291
RGD:1600115
G Xpc XPC complex subunit, DNA damage recognition and repair factor JBrowse link 4 123,134,457 123,161,985 RGD:1624291
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:1624291
G Fbxo31 F-box protein 31 JBrowse link 19 53,487,610 53,625,673 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link 9 94,425,191 94,550,431 RGD:1624291
G Rfwd3 ring finger and WD repeat domain 3 JBrowse link 19 42,960,597 42,971,894 RGD:1624291
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:1624291
G Rps27l ribosomal protein S27-like JBrowse link 8 72,741,155 72,746,090 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07049960.1 RGD:13792537
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Brsk1 BR serine/threonine kinase 1 JBrowse link 1 72,701,281 72,727,061 RGD:1624291
G Brsk2 BR serine/threonine kinase 2 JBrowse link 1 214,918,757 214,940,883 RGD:8554801
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:2316029
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:1624291
RGD:13792537
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link 10 84,780,644 84,789,800 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Clspn claspin JBrowse link 5 144,577,670 144,617,507 RGD:1624291
RGD:13792537
G Donson DNA replication fork stabilization factor DONSON JBrowse link 11 31,834,608 31,847,751 RGD:1624291
G Foxn3 forkhead box N3 JBrowse link 6 123,183,720 123,577,719 RGD:1624291
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1624291
RGD:1600115
G Ier3 immediate early response 3 JBrowse link 20 3,438,798 3,440,002 RGD:1624291
G LOC100302465 hypothetical LOC100302465 JBrowse link 1 206,324,763 206,417,143 RGD:1624291
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase JBrowse link 4 147,744,673 147,756,462 RGD:1624291
G Mre11 MRE11 homolog, double strand break repair nuclease JBrowse link 8 13,304,355 13,350,329 RGD:1624291
RGD:13792537
RGD:1600115
G Mrnip MRN complex interacting protein JBrowse link 10 35,680,687 35,704,685 RGD:1624291
G Nbn nibrin JBrowse link 5 29,622,347 29,656,877 RGD:1624291
RGD:13792537
RGD:1600115
G Nop53 NOP53 ribosome biogenesis factor JBrowse link 1 77,836,522 77,843,991 RGD:1624291
G Syf2 SYF2 pre-mRNA-splicing factor JBrowse link 5 153,269,638 153,277,562 RGD:1624291
G Taok1 TAO kinase 1 JBrowse link 10 62,542,870 62,630,341 RGD:1600115
RGD:1624291
G Taok2 TAO kinase 2 JBrowse link 1 198,301,789 198,354,601 RGD:1600115
RGD:1624291
G Taok3 TAO kinase 3 JBrowse link 12 45,037,951 45,116,593 RGD:1600115
RGD:1624291
G Ticrr TOPBP1-interacting checkpoint and replication regulator JBrowse link 1 141,391,738 141,433,615 RGD:13792537
G Topbp1 DNA topoisomerase II binding protein 1 JBrowse link 8 111,790,655 111,835,224 RGD:13792537
G Trim39 tripartite motif-containing 39 JBrowse link 20 2,500,691 2,514,546 RGD:1600115
RGD:1624291
negative regulation of mitotic DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 JBrowse link 20 3,329,677 3,344,286 RGD:1600115
RGD:1624291
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rint1 RAD50 interactor 1 JBrowse link 4 7,851,602 7,885,446 RGD:1624291
RGD:13792537
signal transduction involved in intra-S DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:1624291
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA-activated, catalytic subunit JBrowse link 11 89,293,547 89,510,948 RGD:1624291
signal transduction involved in mitotic G2 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      cell cycle checkpoint 188
        DNA integrity checkpoint 126
          DNA damage checkpoint 116
            mitotic DNA damage checkpoint 65
              detection of stimulus involved in mitotic DNA damage checkpoint + 0
              intra-S DNA damage checkpoint + 15
              mitotic G1 DNA damage checkpoint + 20
              mitotic G2 DNA damage checkpoint + 29
              negative regulation of mitotic DNA damage checkpoint + 1
              positive regulation of mitotic DNA damage checkpoint + 0
              regulation of mitotic DNA damage checkpoint + 2
              signal transduction involved in mitotic DNA damage checkpoint + 16
Path 2
Term Annotations click to browse term
  biological_process 19858
    biological regulation 13636
      regulation of biological process 12959
        negative regulation of biological process 5617
          negative regulation of cellular process 5079
            negative regulation of cell cycle 461
              cell cycle checkpoint 188
                mitotic cell cycle checkpoint 134
                  mitotic DNA integrity checkpoint 71
                    mitotic DNA damage checkpoint 65
                      detection of stimulus involved in mitotic DNA damage checkpoint + 0
                      intra-S DNA damage checkpoint + 15
                      mitotic G1 DNA damage checkpoint + 20
                      mitotic G2 DNA damage checkpoint + 29
                      negative regulation of mitotic DNA damage checkpoint + 1
                      positive regulation of mitotic DNA damage checkpoint + 0
                      regulation of mitotic DNA damage checkpoint + 2
                      signal transduction involved in mitotic DNA damage checkpoint + 16
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.