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ONTOLOGY REPORT - ANNOTATIONS


Term:G1 DNA damage checkpoint
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Accession:GO:0044783 term browser browse the term
Definition:A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase in the cell cycle in response to DNA damage.
Synonyms:exact_synonym: G1/S DNA damage checkpoint


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G1 DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wac WW domain containing adaptor with coiled-coil ISO (PMID:21329877) RGD PMID:21329877 NCBI chr17:60,887,606...60,946,630
Ensembl chr17:60,888,017...60,946,426
JBrowse link
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp2 caspase 2 ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO (PMID:15149599) RGD PMID:15149599 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain ISO
IBA
(PMID:21726810)
PMID:21873635
RGD PMID:21726810, PMID:21873635 RGD:13792537 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588
JBrowse link
G Mdm2 MDM2 proto-oncogene ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Muc1 mucin 1, cell surface associated ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Pidd1 p53-induced death domain protein 1 ISO (PMID:21726810) RGD PMID:21726810 NCBI chr 1:214,418,751...214,423,959
Ensembl chr 1:214,419,240...214,423,881
JBrowse link
G Pml PML nuclear body scaffold ISO (MGI:3580934|PMID:15626733) RGD PMID:15626733 MGI:3580934 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:134,804,128...134,941,912
Ensembl chr 6:134,804,141...134,939,358
JBrowse link
G Rbm38 RNA binding motif protein 38 ISO (PMID:17050675) RGD PMID:17050675 NCBI chr 3:171,037,891...171,050,500
Ensembl chr 3:171,037,957...171,050,475
JBrowse link
G Rpl26 ribosomal protein L26 ISO (PMID:16213212)
(MGI:5882892|PMID:16213212)
RGD PMID:16213212 MGI:5882892 NCBI chr10:55,492,417...55,495,547
Ensembl chr10:55,492,404...55,496,012
JBrowse link
G Sox4 SRY-box transcription factor 4 ISO (PMID:19234109) RGD PMID:19234109 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Tp53 tumor protein p53 ISO (PMID:16213212)
MGI:108027 (MGI:3589512|PMID:16107883)
RGD PMID:16107883, PMID:16213212 MGI:3589512 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 ISO
ISS
(PMID:19412162)
GO_REF:0000024
RGD
UniProt
PMID:19412162 GO_REF:0000024 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Dgkz diacylglycerol kinase zeta ISO UniProtKB:P06400 (PMID:16286473) RGD PMID:16286473 NCBI chr 3:80,844,002...80,886,487
Ensembl chr 3:80,844,005...80,875,817
JBrowse link
G Fbxo31 F-box protein 31 IEA
ISS
ISO
GO_REF:0000002
GO_REF:0000024
(PMID:19412162)
InterPro
UniProt
RGD
PMID:19412162 GO_REF:0000002, GO_REF:0000024 NCBI chr19:53,487,610...53,625,673
Ensembl chr19:53,487,613...53,625,673
JBrowse link
G Gigyf2 GRB10 interacting GYF protein 2 ISO MGI:4126459 (MGI:4366664|PMID:19744960) RGD PMID:19744960 MGI:4366664 NCBI chr 9:94,425,191...94,550,431
Ensembl chr 9:94,425,252...94,550,431
JBrowse link
G Rfwd3 ring finger and WD repeat domain 3 ISO (PMID:20173098) RGD PMID:20173098 NCBI chr19:42,960,597...42,971,894
Ensembl chr19:42,964,586...42,972,101
JBrowse link
G Rpa2 replication protein A2 ISO (PMID:21731742) RGD PMID:21731742 NCBI chr 5:150,957,041...150,967,597
Ensembl chr 5:150,957,001...150,968,269
JBrowse link
G Rps27l ribosomal protein S27-like ISO (PMID:18056458) RGD PMID:18056458 NCBI chr 8:72,741,155...72,746,090
Ensembl chr 8:72,741,155...72,746,090
JBrowse link
G Tp53 tumor protein p53 ISO (PMID:7958916)
(MGI:3589512|PMID:16107883)
RGD PMID:7958916, PMID:16107883 MGI:3589512 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkdc protein kinase, DNA-activated, catalytic subunit ISO (PMID:21731742) RGD PMID:21731742 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    cellular process 18792
      cell cycle checkpoint 165
        DNA integrity checkpoint 125
          DNA damage checkpoint 115
            G1 DNA damage checkpoint 21
              detection of stimulus involved in G1 DNA damage checkpoint + 0
              intracellular signal transduction involved in G1 DNA damage checkpoint + 13
              mitotic G1 DNA damage checkpoint + 20
Path 2
Term Annotations click to browse term
  biological_process 20020
    biological regulation 13769
      regulation of biological process 13071
        regulation of cellular process 12556
          negative regulation of cellular process 5156
            negative regulation of cell cycle 443
              cell cycle checkpoint 165
                DNA integrity checkpoint 125
                  DNA damage checkpoint 115
                    G1 DNA damage checkpoint 21
                      detection of stimulus involved in G1 DNA damage checkpoint + 0
                      intracellular signal transduction involved in G1 DNA damage checkpoint + 13
                      mitotic G1 DNA damage checkpoint + 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.