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Term:G-quadruplex DNA unwinding
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Accession:GO:0044806 term browser browse the term
Definition:The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.

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G-quadruplex DNA unwinding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLM BLM RecQ like helicase ISO (PMID:11735402)
BHF-UCL PMID:11735402, PMID:26195664 MGI:MGI:5700122 NCBI chr15:69,407,248...69,508,070
Ensembl chr15:88,607,157...88,707,864
JBrowse link
G DDX11 DEAD/H-box helicase 11 ISO (PMID:26503245) UniProtKB PMID:26503245 NCBI chr12:55,176,165...55,207,123 JBrowse link
G DHX36 DEAH-box helicase 36 ISO (MGI:MGI:6201778|PMID:25611385)
(PMID:16150737), (PMID:18842585)
UniProt PMID:16150737, PMID:18842585, PMID:25611385 MGI:MGI:6201778 NCBI chr 3:151,331,468...151,382,406
Ensembl chr 3:158,885,541...158,935,871
JBrowse link
G DHX9 DExH-box helicase 9 ISO (PMID:21561811) UniProtKB PMID:21561811 NCBI chr 1:158,355,472...158,404,178
Ensembl chr 1:162,006,822...162,055,833
JBrowse link
G HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 7:26,835,881...26,846,578
Ensembl chr 7:26,439,443...26,449,985
JBrowse link
G WRN WRN RecQ like helicase ISO (MGI:MGI:5700122|PMID:26195664)
BHF-UCL PMID:11735402, PMID:26195664 MGI:MGI:5700122 NCBI chr 8:30,353,643...30,492,978
Ensembl chr 8:27,541,145...27,679,855
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 12529
    cellular process 11625
      cellular component organization or biogenesis 4979
        cellular component organization 4899
          organelle organization 3022
            chromosome organization 877
              DNA conformation change 167
                DNA geometric change 33
                  G-quadruplex DNA unwinding 6
                    negative regulation of G-quadruplex DNA unwinding 0
                    positive regulation of G-quadruplex DNA unwinding 0
                    regulation of G-quadruplex DNA unwinding + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.