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Term:G-quadruplex DNA unwinding
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Accession:GO:0044806 term browser browse the term
Definition:The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.

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G-quadruplex DNA unwinding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase ISO
UniProtKB:O09053 (MGI:MGI:5700122|PMID:26195664)
RGD PMID:11735402, PMID:26195664, PMID:21873635 MGI:MGI:5700122, RGD:13792537 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Ddx11 DEAD/H-box helicase 11 ISO (PMID:26503245) RGD PMID:26503245 NCBI chr 9:114,113,642...114,133,908
Ensembl chr 9:114,111,580...114,132,492
JBrowse link
G Dhx36 DEAH-box helicase 36 ISS
(PMID:16150737), (PMID:18842585)
PMID:16150737, PMID:18842585, PMID:25611385 GO_REF:0000024, MGI:MGI:6201778 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:21561811) RGD PMID:21561811 NCBI chr13:70,885,503...70,922,278
Ensembl chr13:70,885,504...70,922,245
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IDA PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Wrn WRN RecQ like helicase ISO
UniProtKB:O88700 (MGI:MGI:5700122|PMID:26195664)
RGD PMID:11735402, PMID:26195664, PMID:21873635 MGI:MGI:5700122, RGD:13792537 NCBI chr16:62,483,773...62,619,018
Ensembl chr16:62,483,761...62,615,375
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 20014
    cellular process 18788
      cellular component organization or biogenesis 6766
        cellular component organization 6510
          organelle organization 4073
            chromosome organization 1250
              DNA conformation change 312
                DNA geometric change 94
                  G-quadruplex DNA unwinding 6
                    negative regulation of G-quadruplex DNA unwinding 0
                    positive regulation of G-quadruplex DNA unwinding 0
                    regulation of G-quadruplex DNA unwinding + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.