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Term:G-quadruplex DNA unwinding
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Accession:GO:0044806 term browser browse the term
Definition:The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.

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G-quadruplex DNA unwinding term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase ISO (PMID:11735402)
BHF-UCL PMID:11735402, PMID:26195664 MGI:MGI:5700122 NCBI chrNW_004936483:16,194,092...16,295,803 JBrowse link
G Ddx11 DEAD/H-box helicase 11 ISO (PMID:26503245) UniProtKB PMID:26503245 NCBI chrNW_004936606:181,457...209,286 JBrowse link
G Dhx36 DEAH-box helicase 36 ISO (PMID:16150737), (PMID:18842585)
UniProt PMID:16150737, PMID:18842585, PMID:25611385 MGI:MGI:6201778 NCBI chrNW_004936519:1,946,684...1,987,036 JBrowse link
G Dhx9 DExH-box helicase 9 ISO (PMID:21561811) UniProtKB PMID:21561811 NCBI chrNW_004936481:6,896,487...6,934,938 JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 ISO PMID:23184978 BHF-UCL PMID:23184978 RGD:11567256 NCBI chrNW_004936478:2,970,261...2,980,277 JBrowse link
G Wrn WRN RecQ like helicase ISO (PMID:11735402)
BHF-UCL PMID:11735402, PMID:26195664 MGI:MGI:5700122 NCBI chrNW_004936792:862,659...1,005,065 JBrowse link

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  biological_process 11966
    cellular process 11132
      cellular component organization or biogenesis 4888
        cellular component organization 4810
          organelle organization 2973
            chromosome organization 864
              DNA conformation change 160
                DNA geometric change 34
                  G-quadruplex DNA unwinding 6
                    negative regulation of G-quadruplex DNA unwinding 0
                    positive regulation of G-quadruplex DNA unwinding 0
                    regulation of G-quadruplex DNA unwinding + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.